A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

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Fältnamn	Indikatorer	Metadata
000		48304naa a2204417 4500
001		oai:DiVA.org:uu-328990
003		SwePub
008		170908s2017 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:umu-137613
009		oai:lup.lub.lu.se:76c07d58-5f95-438a-b963-22cd17b5560a
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3289902 URI
024	7	a https://doi.org/10.2337/db16-13292 DOI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1376132 URI
024	7	a https://lup.lub.lu.se/record/76c07d58-5f95-438a-b963-22cd17b5560a2 URI
040		a (SwePub)uud (SwePub)umud (SwePub)lu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Manning, Alisau Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Massachusetts Gen Hosp, Dept Med, Ctr Human Genet Res, Boston, MA 02114 USA.;Harvard Med Sch, Dept Med, Boston, MA USA.,Harvard Medical School,Broad Institute4 aut
245	1 0	a A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
264		c 2017-03-24
264	1	b AMER DIABETES ASSOC,c 2017
338		a print2 rdacarrier
520		a To identify novel coding association signals and facilitate characterization of mechanisms influencing glycemic traits and type 2 diabetes risk, we analyzed 109,215 variants derived from exome array genotyping together with an additional 390,225 variants from exome sequence in up to 39,339 normoglycemic individuals from five ancestry groups. We identified a novel association between the coding variant (p.Pro50Thr) in AKT2 and fasting plasma insulin (FI), a gene in which rare fully penetrant mutations are causal for monogenic glycemic disorders. The low-frequency allele is associated with a 12% increase in FI levels. This variant is present at 1.1% frequency in Finns but virtually absent in individuals from other ancestries. Carriers of the FI-increasing allele had increased 2-h insulin values, decreased insulin sensitivity, and increased risk of type 2 diabetes (odds ratio 1.05). In cellular studies, the AKT2-Thr50 protein exhibited a partial loss of function. We extend the allelic spectrum for coding variants in AKT2 associated with disorders of glucose homeostasis and demonstrate bidirectional effects of variants within the pleckstrin homology domain of AKT2.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
653		a AKT1 protein
653		a AKT3 protein
653		a glucose
653		a insulin
653		a messenger RNA
653		a protein kinase B beta
653		a protein serine threonine kinase
653		a unclassified drug
653		a AKT2 protein, human
653		a protein kinase B
653		a Article
653		a cell function
653		a controlled study
653		a diet restriction
653		a Finland
653		a Finn (citizen)
653		a gene expression
653		a gene frequency
653		a gene inactivation
653		a gene mutation
653		a genetic association
653		a genetic risk
653		a genetic susceptibility
653		a genetic variability
653		a genotype
653		a glucose homeostasis
653		a glycemic control
653		a human
653		a human cell
653		a in vitro study
653		a insulin blood level
653		a insulin sensitivity
653		a major clinical study
653		a monogenic disorder
653		a mutational analysis
653		a non insulin dependent diabetes mellitus
653		a penetrance
653		a phenotype
653		a pleckstrin homology domain
653		a priority journal
653		a protein expression
653		a protein function
653		a protein phosphorylation
653		a RNA sequence
653		a single nucleotide polymorphism
653		a whole exome sequencing
653		a African American
653		a allele
653		a Asian continental ancestry group
653		a case control study
653		a Caucasian
653		a genetic predisposition
653		a genetics
653		a Hispanic
653		a insulin resistance
653		a metabolism
653		a odds ratio
653		a African Americans
653		a Alleles
653		a Asian Continental Ancestry Group
653		a Case-Control Studies
653		a Diabetes Mellitus, Type 2
653		a European Continental Ancestry Group
653		a Fasting
653		a Gene Frequency
653		a Genetic Predisposition to Disease
653		a Genotype
653		a Hispanic Americans
653		a Humans
653		a Insulin
653		a Insulin Resistance
653		a Odds Ratio
653		a Proto-Oncogene Proteins c-akt
700	1	a Highland, Heather M.u Univ Texas MD Anderson Canc Ctr, Human Genet Ctr, Houston, TX 77030 USA.;Univ Texas Hlth Sci Ctr Houston, Grad Sch Biomed Sci, Houston, TX 77030 USA.;Univ North Carolina Chapel Hill, Dept Epidemiol, Chapel Hill, NC USA.4 aut
700	1	a Gasser, Jessicau Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Sim, Xuelingu Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.4 aut
700	1	a Tukiainen, Taruu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Massachusetts Gen Hosp, Dept Med, Analyt & Translat Genet Unit, Boston, MA 02114 USA.;Harvard Med Sch, Dept Genet, Boston, MA USA.4 aut
700	1	a Fontanillas, Pierreu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;23andMe, Mountain View, CA USA.4 aut
700	1	a Grarup, Nielsu Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn, Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Rivas, Manuel A.u Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Mahajan, Anubhau Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Locke, Adam E.u Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Cingolani, Pablou McGill Univ, Sch Comp Sci, Montreal, PQ, Canada.;McGill Univ, Montreal, PQ, Canada.;Genome Quebec Innovat Ctr, Montreal, PQ, Canada.4 aut
700	1	a Pers, Tune H.u Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn, Ctr Basic Metab Res, Copenhagen, Denmark.;Boston Childrens Hosp, Div Endocrinol & Genet, Boston, MA USA.;Boston Childrens Hosp, Div Genom, Boston, MA USA.;Boston Childrens Hosp, Ctr Basic & Translat Obes, Boston, MA USA.;Statens Serum Inst, Dept Epidemiol Res, Copenhagen, Denmark.4 aut
700	1	a Vinuela, Anau Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.;Univ Geneva, Sch Med, Dept Genet Med & Dev, Geneva, Switzerland.;Univ Geneva, Inst Genet & Genom Geneva, Geneva, Switzerland.4 aut
700	1	a Brown, Andrew A.u Wellcome Trust Sanger Inst, Hinxton, England.;Oslo Univ Hosp, Norwegian Ctr Mental Disorders Res, Oslo, Norway.;Oslo Univ Hosp, KG Jebsen Ctr Psychosis Res, Div Mental Hlth & Addict, Oslo, Norway.4 aut
700	1	a Wu, Yingu Univ North Carolina Chapel Hill, Dept Genet, Chapel Hill, NC USA.4 aut
700	1	a Flannick, Jasonu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Massachusetts Gen Hosp, Dept Mol Biol, Boston, MA 02114 USA.4 aut
700	1	a Fuchsberger, Christianu Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Gamazon, Eric R.u Univ Chicago, Dept Med, Sect Genet Med, 5841 S Maryland Ave, Chicago, IL 60637 USA.;Univ Amsterdam, Acad Med Ctr, Amsterdam, Netherlands.4 aut
700	1	a Gaulton, Kyle J.u Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Calif San Diego, Dept Pediat, La Jolla, CA 92093 USA.4 aut
700	1	a Im, Hae Kyungu Univ Chicago, Dept Med, Sect Genet Med, 5841 S Maryland Ave, Chicago, IL 60637 USA.4 aut
700	1	a Teslovich, Tanya M.u Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Blackwell, Thomas W.u Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Bork-Jensen, Jetteu Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn, Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Burtt, Noel P.u Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Chen, Yuhuiu Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Green, Toddu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Hartl, Christopheru Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Kang, Hyun Minu Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Kumar, Ashishu Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Basel, Swiss Trop & Publ Hlth Inst, Chron Dis Epidemiol Unit, Basel, Switzerland.4 aut
700	1	a Ladenvall, Claesu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)med-cll
700	1	a Ma, Clementu Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Moutsianas, Loukasu Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Pearson, Richard D.u Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Perry, John R. B.u Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Exeter, Genet Complex Traits, Med Sch, Exeter, Devon, England.;Univ Cambridge, Inst Metab Sci, MRC, Epidemiol Unit, Cambridge, England.4 aut
700	1	a Rayner, N. Williamu Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.;Wellcome Trust Sanger Inst, Dept Human Genet, Hinxton, England.4 aut
700	1	a Robertson, Neil R.u Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.4 aut
700	1	a Scott, Laura J.u Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a van de Bunt, Martijnu Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.4 aut
700	1	a Eriksson, Johan G.u Univ Helsinki, Dept Gen Practice & Primary Hlth Care, Helsinki, Finland.;Univ Helsinki, Unit Gen Practice, Cent Hosp, Helsinki, Finland.;Folkhalsan Res Ctr, Helsinki, Finland.;Vaasa Cent Hosp, Vaasa, Finland.;Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.;Univ Tampere, Dept Clin Chem, Fimlab Labs, Sch Med, Tampere, Finland.4 aut
700	1	a Jula, Anttiu Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Koskinen, Seppou Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Lehtimaki, Terho4 aut
700	1	a Palotie, Aarnou Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Massachusetts Gen Hosp, Dept Med, Ctr Human Genet Res, Boston, MA 02114 USA.;Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn, Ctr Basic Metab Res, Copenhagen, Denmark.;Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.;Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland.;Univ Liverpool, Dept Biostat, Liverpool, Merseyside, England.4 aut
700	1	a Raitakari, Olli T.u Turku Univ Hosp, Dept Clin Physiol & Nucl Med, Turku, Finland.;Univ Turku, Res Ctr Appl & Prevent Cardiovasc Med, Turku, Finland.4 aut
700	1	a Jacobs, Suzanne B. R.u Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Wessel, Jenniferu Fairbanks Sch Publ Hlth, Dept Epidemiol, Indianapolis, IN USA.;Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA.4 aut
700	1	a Chu, Audrey Y.u Brigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.4 aut
700	1	a Scott, Robert A.u Univ Cambridge, Inst Metab Sci, MRC, Epidemiol Unit, Cambridge, England.4 aut
700	1	a Goodarzi, Mark O.u Cedars Sinai Med Ctr, Dept Med, Div Endocrinol Diabet & Metab, Los Angeles, CA 90048 USA.;Cedars Sinai Med Ctr, Dept Biomed Sci, Los Angeles, CA 90048 USA.4 aut
700	1	a Blancher, Christineu Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, High Throughput Genom,Oxford Genom Ctr, Oxford, England.4 aut
700	1	a Buck, Gemmau Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, High Throughput Genom,Oxford Genom Ctr, Oxford, England.4 aut
700	1	a Buck, Davidu Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, High Throughput Genom,Oxford Genom Ctr, Oxford, England.4 aut
700	1	a Chines, Peter S.u NHGRI, NIH, Bethesda, MD 20892 USA.4 aut
700	1	a Gabriel, Staceyu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Gjesing, Anette P.u Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn, Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Groves, Christopher J.u Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.4 aut
700	1	a Hollensted, Metteu Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn, Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Huyghe, Jeroen R.u Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Jackson, Anne U.u Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Jun, Goou Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Justesen, Johanne Marieu Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn, Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Mangino, Massimou Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.,University of Oxford,Broad Institute,Massachusetts General Hospital4 aut
700	1	a Murphy, Jacquelynu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Neville, Mattu Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.4 aut
700	1	a Onofrio, Robertu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Small, Kerrin S.u Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.4 aut
700	1	a Stringham, Heather M.u Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Trakalo, Josephu Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, High Throughput Genom,Oxford Genom Ctr, Oxford, England.4 aut
700	1	a Banks, Ericu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Carey, Jasonu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Carneiro, Mauricio O.u Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a DePristo, Marku Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Farjoun, Yossiu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Fennell, Timothyu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Goldstein, Jacqueline I.u Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Massachusetts Gen Hosp, Dept Med, Analyt & Translat Genet Unit, Boston, MA 02114 USA.4 aut
700	1	a Grant, Georgeu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a de Angelis, Martin Hrabeu German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Expt Genet, Neuherberg, Germany.;German Ctr Diabet Res DZD, Neuherberg, Germany.;Tech Univ Munich, Sch Life Sci Weihenstephan, Inst Expt Genet, Freising Weihenstephan, Germany.4 aut
700	1	a Maguire, Jaredu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Neale, Benjamin M.u Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Massachusetts Gen Hosp, Dept Med, Analyt & Translat Genet Unit, Boston, MA 02114 USA.4 aut
700	1	a Poplin, Ryanu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Purcell, Shaunu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Massachusetts Gen Hosp, Dept Med, Ctr Human Genet Res, Boston, MA 02114 USA.;Icahn Sch Med Mt Sinai, Icahn Inst Genom & Multiscale Biol, Dept Psychiat, New York, NY 10029 USA.4 aut
700	1	a Schwarzmayr, Thomasu German Res Ctr Environm Hlth, Inst Human Genet, Helmholtz Zentrum Munchen, Neuherberg, Germany.4 aut
700	1	a Shakir, Khalidu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.4 aut
700	1	a Smith, Joshua D.u Univ Washington, Sch Med, Dept Genome Sci, Seattle, WA USA.4 aut
700	1	a Strom, Tim M.u German Res Ctr Environm Hlth, Inst Human Genet, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Tech Univ Munich, Inst Human Genet, Neuherberg, Germany.4 aut
700	1	a Wieland, Thomasu German Res Ctr Environm Hlth, Inst Human Genet, Helmholtz Zentrum Munchen, Neuherberg, Germany.4 aut
700	1	a Lindstrom, Jaanau Natl Inst Hlth & Welf, Diabet Prevent Unit, Helsinki, Finland.4 aut
700	1	a Brandslund, Ivanu Univ Southern Denmark, Dept Reg Hlth Res, Odense, Denmark.;Vejle Hosp, Dept Clin Biochem, Vejle, Denmark.4 aut
700	1	a Christensen, Crameru Vejle Hosp, Dept Internal Med & Endocrinol, Vejle, Denmark.4 aut
700	1	a Surdulescu, Gabriela L.u Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.4 aut
700	1	a Lakka, Timo A.u Univ Eastern FinIand, Inst Biomed, Dept Physiol, Kuopio, Finland.;Kuopio Res Inst Exercise Med, Kuopio, Finland.;Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, Kuopio, Finland.4 aut
700	1	a Doney, Alex S. F.u Ninewells Hosp & Med Sch, Med Res Inst, Div Cardiovasc & Diabet Med, Dundee, Scotland.4 aut
700	1	a Nilsson, Peteru Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-pni
700	1	a Wareham, Nicholas J.u Univ Cambridge, Inst Metab Sci, MRC, Epidemiol Unit, Cambridge, England.4 aut
700	1	a Langenberg, Claudiau Univ Cambridge, Inst Metab Sci, MRC, Epidemiol Unit, Cambridge, England.4 aut
700	1	a V. Varga, Tiboru Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-tv_
700	1	a Franks, Paul W.u Lund University,Lunds universitet,Umeå universitet,Medicin,Department of Clinical Sciences, Lund University Diabetes Centre, and Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden; Department of Nutrition, Harvard School of Public Health, Boston, MA,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-plf
700	1	a Rolandsson, Olovu Umeå universitet,Allmänmedicin4 aut0 (Swepub:umu)olro0005
700	1	a Rosengren, Andersu Lund University,Lunds universitet,Diabetes - öpatofysiologi,Forskargrupper vid Lunds universitet,Diabetes - Islet Patophysiology,Lund University Research Groups4 aut0 (Swepub:lu)mphy-aro
700	1	a Farook, Vidya S.u Texas Biomed Res Inst, Dept Genet, San Antonio, TX USA.4 aut
700	1	a Thameem, Farooku Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA.4 aut
700	1	a Puppala, Sobhau Texas Biomed Res Inst, Dept Genet, San Antonio, TX USA.4 aut
700	1	a Kumar, Satishu Texas Biomed Res Inst, Dept Genet, San Antonio, TX USA.4 aut
700	1	a Lehman, Donna M.u Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA.4 aut
700	1	a Jenkinson, Christopher P.u Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA.;South Texas Vet Hlth Care Syst, Res & Dev Serv, San Antonio, TX USA.4 aut
700	1	a Curran, Joanne E.u Texas Biomed Res Inst, Dept Genet, San Antonio, TX USA.4 aut
700	1	a Hale, Daniel Estenu Univ Texas Hlth Sci Ctr San Antonio, Dept Pediat, San Antonio, TX 78229 USA.4 aut
700	1	a Fowler, Sharon P.u Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA.4 aut
700	1	a Arya, Rectoru Univ Texas Hlth Sci Ctr San Antonio, Dept Pediat, San Antonio, TX 78229 USA.4 aut
700	1	a DeFronzo, Ralph A.u Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA.4 aut
700	1	a Abboud, Hanna E.u Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA.4 aut
700	1	a Syvänen, Ann-Christine,d 1950-u Uppsala universitet,Molekylär medicin,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)anncsyva
700	1	a Hicks, Pamela J.u Wake Forest Sch Med, Ctr Genom & Personalized Med Res, Winston Salem, NC USA.;Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC USA.;Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC USA.;Wake Forest Sch Med, Dept Biochem, Winston Salem, NC USA.4 aut
700	1	a Palmer, Nicholette D.u Wake Forest Sch Med, Ctr Genom & Personalized Med Res, Winston Salem, NC USA.;Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC USA.;Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC USA.;Wake Forest Sch Med, Dept Biochem, Winston Salem, NC USA.4 aut
700	1	a Ng, Maggie C. Y.u Wake Forest Sch Med, Ctr Genom & Personalized Med Res, Winston Salem, NC USA.;Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC USA.;Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC USA.4 aut
700	1	a Bowden, Donald W.u Wake Forest Sch Med, Ctr Genom & Personalized Med Res, Winston Salem, NC USA.;Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC USA.;Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC USA.;Wake Forest Sch Med, Dept Biochem, Winston Salem, NC USA.4 aut
700	1	a Freedman, Barry I.u Wake Forest Sch Med, Dept Internal Med, Sect Nephrol, Winston Salem, NC USA.4 aut
700	1	a Esko, Tonuu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.;Boston Childrens Hosp, Div Endocrinol, Boston, MA USA.;Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.4 aut
700	1	a Magi, Reediku Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.4 aut
700	1	a Milani, Liliu Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.4 aut
700	1	a Mihailov, Evelinu Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.4 aut
700	1	a Metspalu, Andresu Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.4 aut
700	1	a Narisu, Narisuu NHGRI, NIH, Bethesda, MD 20892 USA.4 aut
700	1	a Kinnunen, Leenau Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Bonnycastle, Lori L.u NHGRI, NIH, Bethesda, MD 20892 USA.4 aut
700	1	a Swift, Amyu NHGRI, NIH, Bethesda, MD 20892 USA.4 aut
700	1	a Pasko, Dorotau Univ Exeter, Genet Complex Traits, Med Sch, Exeter, Devon, England.4 aut
700	1	a Wood, Andrew R.u Univ Exeter, Genet Complex Traits, Med Sch, Exeter, Devon, England.4 aut
700	1	a Fadista, Joaou Lund Univ, Ctr Diabet, Dept Clin Sci Malmo, Diabet & Endocrinol Unit, Malmo, Sweden.4 aut
700	1	a Pollin, Toni I.u Univ Maryland, Dept Med, Program Personalized & Genom Med, Baltimore, MD 21201 USA.4 aut
700	1	a Barzilai, Niru Albert Einstein Coll Med, Dept Med, New York, NY USA.;Albert Einstein Coll Med, Dept Genet, New York, NY USA.4 aut
700	1	a Atzmon, Gilu Albert Einstein Coll Med, Dept Med, New York, NY USA.;Albert Einstein Coll Med, Dept Genet, New York, NY USA.;Univ Haifa, Fac Nat Sci, Haifa, Israel.4 aut
700	1	a Glaser, Benjaminu Hadassah Hebrew Univ, Endocrinol & Metab Serv, Med Ctr, Jerusalem, Israel.4 aut
700	1	a Thorand, Barbarau German Ctr Diabet Res DZD, Neuherberg, Germany.;German Res Ctr Environm Hlth, Inst Epidemiol 2, Helmholtz Zentrum Munchen, Neuherberg, Germany.4 aut
700	1	a Strauch, Konstantinu German Res Ctr Environm Hlth, Inst Genet Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Ludwig Maximilians Univ Munchen, Inst Med Informat Biometry & Epidemiol, Dept Genet Epidemiol, Munich, Germany.4 aut
700	1	a Peters, Annetteu German Ctr Diabet Res DZD, Neuherberg, Germany.;German Res Ctr Environm Hlth, Inst Epidemiol 2, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Partner Site Munich Heart Alliance, Herz Kreislauf Forsch DZHK, Deutsch Zentrum, Munich, Germany.4 aut
700	1	a Roden, Michaelu Heinrich Heine Univ, Leibniz Ctr Diabet Res, German Diabet Ctr, Inst Clin Diabetol, Dusseldorf, Germany.;Partner Dusseldorf, German Ctr Diabet Res, Dusseldorf, Germany.4 aut
700	1	a Mueller-Nurasyid, Martinau German Res Ctr Environm Hlth, Inst Genet Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Ludwig Maximilians Univ Munchen, Inst Med Informat Biometry & Epidemiol, Dept Genet Epidemiol, Munich, Germany.;Partner Site Munich Heart Alliance, Herz Kreislauf Forsch DZHK, Deutsch Zentrum, Munich, Germany.;Ludwig Maximilians Univ Munchen, Univ Hosp Grosshadern, Dept Med 1, Munich, Germany.4 aut
700	1	a Liang, Limingu Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.;Harvard Sch Publ Hlth, Dept Biostat, Boston, MA USA.4 aut
700	1	a Kriebel, Jenniferu German Ctr Diabet Res DZD, Neuherberg, Germany.;German Res Ctr Environm Hlth, Inst Epidemiol 2, Helmholtz Zentrum Munchen, Neuherberg, Germany.;German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany.4 aut
700	1	a Illig, Thomasu German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Hannover Med Sch, Hannover Unified Biobank, Hannover, Germany.;Hannover Med Sch, Inst Human Genet, Hannover, Germany.4 aut
700	1	a Grallert, Haraldu German Ctr Diabet Res DZD, Neuherberg, Germany.;German Res Ctr Environm Hlth, Inst Epidemiol 2, Helmholtz Zentrum Munchen, Neuherberg, Germany.;German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany.4 aut
700	1	a Gieger, Christianu German Res Ctr Environm Hlth, Inst Genet Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany.4 aut
700	1	a Meisinger, Christau German Res Ctr Environm Hlth, Inst Epidemiol 2, Helmholtz Zentrum Munchen, Neuherberg, Germany.4 aut
700	1	a Lannfelt, Lu Uppsala universitet,Geriatrik4 aut0 (Swepub:uu)lalan021
700	1	a Musani, Solomon K.u Univ Mississippi, Med Ctr, Jackson Heart Study, Jackson, MS 39216 USA.4 aut
700	1	a Griswold, Michaelu Univ Mississippi, Med Ctr, Ctr Biostat & Bioinformat, Jackson, MS 39216 USA.4 aut
700	1	a Taylor, Herman A., Jr.u Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA.4 aut
700	1	a Wilson, Gregory, Sr.u Jackson State Univ, Coll Publ Serv, Jackson, MS USA.4 aut
700	1	a Correa, Adolfou Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA.4 aut
700	1	a Oksa, Heikkiu Pirkanmaa Hosp Dist, Tampere, Finland.4 aut
700	1	a Scott, William R.u Imperial Coll London, Dept Epidemiol & Biostat, London, England.4 aut
700	1	a Afzal, Uzmau Imperial Coll London, Dept Epidemiol & Biostat, London, England.4 aut
700	1	a Tan, Sian-Tsungu Imperial Coll London, Natl Heart & Lung Inst, Cardiovasc Sci, London, England.;Ealing Hosp NHS Trust, Dept Cardiol, Southall, Middx, England.4 aut
700	1	a Loh, Marieu Imperial Coll London, Dept Epidemiol & Biostat, London, England.;Univ Oulu, Inst Hlth Sci, Oulu, Finland.;ASTAR, Translat Lab Genet Med, Singapore, Singapore.4 aut
700	1	a Chambers, John C.u Imperial Coll London, Dept Epidemiol & Biostat, London, England.;Ealing Hosp NHS Trust, Dept Cardiol, Southall, Middx, England.;Imperial Coll London, Imperial Coll Healthcare NHS Trust, London, England.4 aut
700	1	a Sehmi, Jobanpreetu Imperial Coll London, Natl Heart & Lung Inst, Cardiovasc Sci, London, England.;Ealing Hosp NHS Trust, Dept Cardiol, Southall, Middx, England.4 aut
700	1	a Kooner, Jaspal Singhu Imperial Coll London, Natl Heart & Lung Inst, Cardiovasc Sci, London, England.4 aut
700	1	a Lehne, Benjaminu Imperial Coll London, Dept Epidemiol & Biostat, London, England.4 aut
700	1	a Cho, Yoon Shinu Hallym Univ, Dept Biomed Sci, Chunchon, South Korea.4 aut
700	1	a Lee, Jong-Youngu Minist Hlth & Welf, Seoul, South Korea.4 aut
700	1	a Han, Bok-Gheeu Korea Natl Res Inst Hlth, Ctr Genome Sci, Chungcheongbuk Do, South Korea.4 aut
700	1	a Karajamaki, Annemariu Vaasa Hlth Care Ctr, Vaasa, Finland.;Vaasa Cent Hosp, Dept Primary Hlth Care, Vaasa, Finland.4 aut
700	1	a Qi, Qibinu Harvard Sch Publ Hlth, Dept Nutr, Boston, MA USA.;Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, New York, NY USA.4 aut
700	1	a Qi, Luu Harvard Sch Publ Hlth, Dept Nutr, Boston, MA USA.;Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA.;Harvard Med Sch, Boston, MA USA.4 aut
700	1	a Huang, Jinyanu Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.4 aut
700	1	a Hu, Frank B.u Harvard Sch Publ Hlth, Dept Nutr, Boston, MA USA.;Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.4 aut
700	1	a Melander, Olleu Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups4 aut0 (Swepub:lu)endo-ome
700	1	a Orho-Melander, Marjuu Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups4 aut0 (Swepub:lu)endo-mor
700	1	a Below, Jennifer E.u Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Human Genet Ctr, Houston, TX 77030 USA.4 aut
700	1	a Aguilar, Davidu Baylor Coll Med, Cardiovasc Div, Houston, TX 77030 USA.4 aut
700	1	a Wong, Tien Yinu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore, Singapore.4 aut
700	1	a Liu, Jianjunu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.;ASTAR, Genome Inst Singapore, Div Human Genet, Singapore, Singapore.4 aut
700	1	a Khor, Chiea-Chuenu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.;Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore, Singapore.;ASTAR, Genome Inst Singapore, Div Human Genet, Singapore, Singapore.;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Paediat, Singapore, Singapore.4 aut
700	1	a Chia, Kee Sengu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.4 aut
700	1	a Lim, Wei Yenu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.4 aut
700	1	a Cheng, Ching-Yuu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.;Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore, Singapore.;Duke NUS Grad Med Sch Singapore, Ctr Quantitat Med, Off Clin Sci, Singapore, Singapore.4 aut
700	1	a Chan, Edmundu Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore.4 aut
700	1	a Tai, E. Shyongu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore.;Duke NUS Grad Med Sch Singapore, Cardiovasc Metab Disorders Program, Singapore, Singapore.4 aut
700	1	a Aung, Tinu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore.;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore, Singapore.4 aut
700	1	a Linneberg, Allanu Glostrup Univ Hosp, Res Ctr Prevent & Hlth, Glostrup, Denmark.;Rigshosp, Dept Clin Expt Res, Glostrup, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, Dept Clin Med, Copenhagen, Denmark.4 aut
700	1	a Isomaa, Bou Folkhalsan Res Ctr, Helsinki, Finland.;Dept Social Serv & Hlth Care, Pietarsaari, Finland.4 aut
700	1	a Meitinger, Thomasu German Res Ctr Environm Hlth, Inst Human Genet, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Tech Univ Munich, Inst Human Genet, Neuherberg, Germany.;Partner Site Munich Heart Alliance, Herz Kreislauf Forsch DZHK, Deutsch Zentrum, Munich, Germany.4 aut
700	1	a Tuomi, Tiinamaijau Folkhalsan Res Ctr, Helsinki, Finland.;Helsinki Univ Cent Hosp, Dept Endocrinol, Helsinki, Finland.4 aut
700	1	a Hakaste, Liisau Folkhalsan Res Ctr, Helsinki, Finland.4 aut
700	1	a Kravic, Jasminau Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Diabetiska komplikationer,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Diabetic Complications4 aut0 (Swepub:lu)med-jik
700	1	a Jorgensen, Marit E.u Steno Diabet Ctr, Gentofte, Denmark.4 aut
700	1	a Lauritzen, Torstenu Aarhus Univ, Dept Publ Hlth, Sect Gen Practice, Aarhus, Denmark.4 aut
700	1	a Deloukas, Panosu Wellcome Trust Sanger Inst, Dept Human Genet, Hinxton, England.4 aut
700	1	a Stirrups, Kathleen E.u Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England.;Univ Cambridge, Dept Haematol, Cambridge, England.4 aut
700	1	a Owen, Katharine R.u Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.;Oxford Univ Hosp Trust, Oxford NIHR Biomed Res Ctr, Oxford, England.4 aut
700	1	a Farmer, Andrew J.u Univ Oxford, Dept Primary Care Hlth Sci, Oxford, England.4 aut
700	1	a Frayling, Timothy M.u Univ Exeter, Genet Complex Traits, Med Sch, Exeter, Devon, England.4 aut
700	1	a O'Rahilly, Stephen P.u Univ Cambridge, Inst Metab Sci, Med Res Labs, Cambridge, England.4 aut
700	1	a Walker, Marku Univ Newcastle, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, England.4 aut
700	1	a Levy, Jonathan C.u Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.4 aut
700	1	a Hodgkiss, Dylanu Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.4 aut
700	1	a Hattersley, Andrew T.u Univ Exeter, Sch Med, Exeter, Devon, England.4 aut
700	1	a Kuulasmaa, Teemuu Univ Eastern Finland, Fac Hlth Sci, Inst Clin Med, Internal Med, Kuopio, Finland.4 aut
700	1	a Stancakova, Alenau Univ Eastern Finland, Fac Hlth Sci, Inst Clin Med, Internal Med, Kuopio, Finland.4 aut
700	1	a Barroso, Inesu Wellcome Trust Sanger Inst, Dept Human Genet, Hinxton, England.;Univ Cambridge, Inst Metab Sci, Med Res Labs, Cambridge, England.4 aut
700	1	a Bharadwaj, Dwaipayanu CSIR Inst Genom & Integrat Biol, Funct Genom Unit, New Delhi, India.4 aut
700	1	a Chan, Julianau Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China.;Chinese Univ Hong Kong, Li Ka Shing Inst Hlth Sci, Hong Kong, Hong Kong, Peoples R China.;Chinese Univ Hong Kong, Hong Kong Inst Diabet & Obes, Hong Kong, Hong Kong, Peoples R China.4 aut
700	1	a Chandak, Giriraj R.u CSIR Ctr Cellular Mol Biol, Hyderabad, Andhra Pradesh, India.4 aut
700	1	a Daly, Mark J.u Massachusetts Gen Hosp, Dept Med, Analyt & Translat Genet Unit, Boston, MA 02114 USA.4 aut
700	1	a Donnelly, Peter J.u Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Dept Stat, Oxford, England.4 aut
700	1	a Ebrahim, Shah B.u Ctr Chron Dis Control, New Delhi, India. Imperial Coll London, MRC, PHE Ctr Environm & Hlth, London, England.4 aut
700	1	a Elliott, Paulu Imperial Coll London, Dept Epidemiol & Biostat, London, England.4 aut
700	1	a Fingerlin, Tashau Univ Colorado, Colorado Sch Publ Hlth, Dept Epidemiol, Aurora, CO USA.4 aut
700	1	a Froguel, Philippeu CNRS, Inst Biol Lille, Genom & Mol Physiol, Lille, France.4 aut
700	1	a Hu, Chengu Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Shanghai Diabet Inst, Dept Endocrinol & Metab, Shanghai, Peoples R China.4 aut
700	1	a Jia, Weipingu Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Shanghai Diabet Inst, Dept Endocrinol & Metab, Shanghai, Peoples R China.4 aut
700	1	a Ma, Ronald C. W.u Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China.;Chinese Univ Hong Kong, Li Ka Shing Inst Hlth Sci, Hong Kong, Hong Kong, Peoples R China.;Chinese Univ Hong Kong, Hong Kong Inst Diabet & Obes, Hong Kong, Hong Kong, Peoples R China.4 aut
700	1	a McVean, Gileanu Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Park, Taesungu Seoul Natl Univ, Interdisciplinary Program Bioinformat, Seoul, South Korea.;Seoul Natl Univ, Dept Stat, Seoul, South Korea.;Univ Cambridge, Dept Publ Hlth & Primary Care, Inst Publ Hlth, Cambridge, England.4 aut
700	1	a Prabhakaran, Dorairaju Ctr Chron Dis Control, New Delhi, India. Imperial Coll London, MRC, PHE Ctr Environm & Hlth, London, England.4 aut
700	1	a Sandhu, Manjinderu Wellcome Trust Sanger Inst, Dept Human Genet, Hinxton, England.;Univ Cambridge, Dept Publ Hlth & Primary Care, Inst Publ Hlth, Cambridge, England.4 aut
700	1	a Scott, Jamesu Imperial Coll London, Natl Heart & Lung Inst, Cardiovasc Sci, London, England.4 aut
700	1	a Sladek, Robu McGill Univ, Montreal, PQ, Canada.;Genome Quebec Innovat Ctr, Montreal, PQ, Canada.;McGill Univ, Dept Human Genet, Montreal, PQ, Canada.;McGill Univ, Dept Med, Div Endocrinol & Metab, Montreal, PQ, Canada.4 aut
700	1	a Tandon, Nikhilu All India Inst Med Sci, Dept Endocrinol & Metab, New Delhi, India.4 aut
700	1	a Teo, Yik Yingu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.;Natl Univ Singapore, Inst Life Sci, Singapore, Singapore.;Natl Univ Singapore, Dept Stat & Appl Probabil, Singapore, Singapore.4 aut
700	1	a Zeggini, Eleftheriau Wellcome Trust Sanger Inst, Dept Human Genet, Hinxton, England.4 aut
700	1	a Watanabe, Richard M.u Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA USA.;Univ Southern Calif, Keck Sch Med, Dept Physiol & Biophys, Los Angeles, CA USA.;Univ Southern Calif, Keck Sch Med, Diabet & Obes Res Inst, Los Angeles, CA USA.4 aut
700	1	a Koistinen, Heikki A.u Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.;Univ Helsinki, Dept Med, Helsinki, Finland.;Univ Helsinki, Abdominal Ctr, Endocrinol, Helsinki, Finland.;Univ Helsinki, Cent Hosp, Helsinki, Finland.;Minerva Fdn, Inst Med Res, Helsinki, Finland.4 aut
700	1	a Kesaniemi, Y. Anterou Univ Oulu, Inst Clin Med, Fac Med, Oulu, Finland.4 aut
700	1	a Uusitupa, Mattiu Univ Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio, Finland.4 aut
700	1	a Spector, Timothy D.u Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.4 aut
700	1	a Salomaa, Veikkou Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Rauramaa, Raineru Fdn Res Hlth Exercise & Nutr, Kuopio Res Inst Exercise Med, Kuopio, Finland.4 aut
700	1	a Palmer, Colin N. A.u Ninewells Hosp & Med Sch, Med Res Inst, Pat Macpherson Ctr Pharmacogenet & Pharmacogenom, Dundee, Scotland.4 aut
700	1	a Prokopenko, Ingau Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.;Imperial Coll London, Sch Publ Hlth, Dept Genom Common Dis, London, England.4 aut
700	1	a Morris, Andrew D.u Ninewells Hosp & Med Sch, Clin Res Ctr, Div Mol Med, Dundee, Scotland.4 aut
700	1	a Bergman, Richard N.u Cedars Sinai Med Ctr, Diabet & Obes Res Inst, Los Angeles, CA 90048 USA.4 aut
700	1	a Collins, Francis S.u NHGRI, NIH, Bethesda, MD 20892 USA.4 aut
700	1	a Lind, Larsu Uppsala universitet,Kardiovaskulär epidemiologi4 aut0 (Swepub:uu)larslind
700	1	a Ingelsson, Eriku Uppsala Univ, Dept Med Sci, Mol Med & Sci Life Lab, Uppsala, Sweden.;Stanford Univ, Dept Med, Sch Med, Div Cardiovasc Med, Stanford, CA 94305 USA.4 aut
700	1	a Tuomilehto, Jaakkou Natl Inst Hlth & Welf, Diabet Prevent Unit, Helsinki, Finland.;Danube Univ Krems, Ctr Vasc Prevent, Krems, Austria.;King Abdulaziz Univ, Diabet Res Grp, Jeddah, Saudi Arabia.;Dasman Diabet Inst, Dasman, Kuwait.4 aut
700	1	a Karpe, Fredriku Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.;Oxford Univ Hosp Trust, Oxford NIHR Biomed Res Ctr, Oxford, England.4 aut
700	1	a Groop, Leifu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)endo-lgr
700	1	a Jorgensen, Torbenu Glostrup Univ Hosp, Res Ctr Prevent & Hlth, Glostrup, Denmark.;Aalborg Univ, Fac Med, Aalborg, Denmark.4 aut
700	1	a Hansen, Torbenu Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn, Ctr Basic Metab Res, Copenhagen, Denmark.;Univ Southern Denmark, Fac Hlth Sci, Odense, Denmark.4 aut
700	1	a Pedersen, Olufu Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn, Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Kuusisto, Johannau Univ Eastern Finland, Fac Hlth Sci, Inst Clin Med, Internal Med, Kuopio, Finland.;Kuopio Univ Hosp, Kuopio, Finland.4 aut
700	1	a Abecasis, GonOalou Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Bell, Graeme I.u Univ Chicago, Dept Med, 5841 S Maryland Ave, Chicago, IL 60637 USA.;Univ Chicago, Dept Human Genet, Chicago, IL 60637 USA.4 aut
700	1	a Blangero, Johnu Texas Biomed Res Inst, Dept Genet, San Antonio, TX USA.4 aut
700	1	a Cox, Nancy J.u Univ Chicago, Dept Med, Sect Genet Med, 5841 S Maryland Ave, Chicago, IL 60637 USA.4 aut
700	1	a Duggirala, Ravindranathu Texas Biomed Res Inst, Dept Genet, San Antonio, TX USA.4 aut
700	1	a Seielstad, Marku Univ Calif San Francisco, Dept Lab Med, Inst Human Genet, San Francisco, CA 94143 USA.;Blood Syst Res Inst, San Francisco, CA USA.4 aut
700	1	a Wilson, James G.u Univ Mississippi, Med Ctr, Dept Physiol & Biophys, Jackson, MS 39216 USA.4 aut
700	1	a Dupuis, Joseeu Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA.;NHLBI, Framingham Heart Study, Framingham, MA USA.4 aut
700	1	a Ripatti, Samuliu Wellcome Trust Sanger Inst, Hinxton, England.;Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland.;Univ Helsinki, Hjelt Inst, Helsinki, Finland.4 aut
700	1	a Hanis, Craig L.u Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Human Genet Ctr, Houston, TX 77030 USA.4 aut
700	1	a Florez, Jose C.u Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Massachusetts Gen Hosp, Dept Med, Ctr Human Genet Res, Boston, MA 02114 USA.;Harvard Med Sch, Dept Med, Boston, MA USA.;Massachusetts Gen Hosp, Dept Med, Diabet Res Ctr, Diabet Unit, Boston, MA 02114 USA.4 aut
700	1	a Mohlke, Karen L.u Univ North Carolina Chapel Hill, Dept Genet, Chapel Hill, NC USA.4 aut
700	1	a Meigs, James B.u Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Harvard Med Sch, Dept Med, Boston, MA USA.;Massachusetts Gen Hosp, Div Gen Internal Med, Boston, MA 02114 USA.4 aut
700	1	a Laakso, Markkuu Univ Eastern Finland, Fac Hlth Sci, Inst Clin Med, Internal Med, Kuopio, Finland.;Kuopio Univ Hosp, Kuopio, Finland.4 aut
700	1	a Morris, Andrew P.u Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.;Univ Liverpool, Dept Biostat, Liverpool, Merseyside, England.4 aut
700	1	a Boehnke, Michaelu Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Sch Publ Hlth, Ctr Stat Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Altshuler, Davidu Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Harvard Med Sch, Dept Med, Boston, MA USA.;Harvard Med Sch, Dept Genet, Boston, MA USA.;Massachusetts Gen Hosp, Dept Mol Biol, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Dept Med, Diabet Res Ctr, Diabet Unit, Boston, MA 02114 USA.;MIT, Dept Biol, Cambridge, MA USA.4 aut
700	1	a McCarthy, Mark I.u Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.;Oxford Univ Hosp Trust, Oxford NIHR Biomed Res Ctr, Oxford, England.4 aut
700	1	a Gloyn, Anna L.u Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.;Oxford Univ Hosp Trust, Oxford NIHR Biomed Res Ctr, Oxford, England.4 aut
700	1	a Lindgren, Cecilia M.u Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Li Ka Shing Ctr Hlth Informat & Discovery, Big Data Inst, Oxford, England.4 aut
710	2	a Broad Inst, Program Med & Populat Genet, Cambridge, MA 02142 USA.;Massachusetts Gen Hosp, Dept Med, Ctr Human Genet Res, Boston, MA 02114 USA.;Harvard Med Sch, Dept Med, Boston, MA USA.b Harvard Medical School4 org
710	2	a et al.
773	0	t Diabetesd : AMER DIABETES ASSOCg 66:7, s. 2019-2032q 66:7<2019-2032x 0012-1797x 1939-327X
856	4	u https://diabetes.diabetesjournals.org/content/diabetes/66/7/2019.full.pdf
856	4	u http://dx.doi.org/10.2337/db16-1329y FULLTEXT
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-328990
856	4 8	u https://doi.org/10.2337/db16-1329
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-137613
856	4 8	u https://lup.lub.lu.se/record/76c07d58-5f95-438a-b963-22cd17b5560a

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Endokrinologi oc ...

Artiklar i publikationen: Diabetes

Av lärosätet: Uppsala universitet; Umeå universitet; Lunds universitet

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