WFRF:(Grillo A A)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 18483naa a2201801 4500 | |
| 001 | oai:gup.ub.gu.se/325556 | |
| 003 | SwePub | |
| 008 | 240528s2022 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:umu-198052 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/3255562 URI |
| 024 | 7 | a https://doi.org/10.1002/ana.264312 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1980522 URI |
| 040 | a (SwePub)gud (SwePub)umu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Scutelnic, Adrianu Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland4 aut |
| 245 | 1 0 | a Management of Cerebral Venous Thrombosis Due to Adenoviral COVID-19 Vaccination. |
| 264 | c 2022-07-04 | |
| 264 | 1 | b Wiley,c 2022 |
| 520 | a Cerebral venous thrombosis (CVT) caused by vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare adverse effect of adenovirus-based severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) vaccines. In March 2021, after autoimmune pathogenesis of VITT was discovered, treatment recommendations were developed. These comprised immunomodulation, non-heparin anticoagulants, and avoidance of platelet transfusion. The aim of this study was to evaluate adherence to these recommendations and its association with mortality.We used data from an international prospective registry of patients with CVT after the adenovirus-based SARS-CoV-2 vaccination. We analyzed possible, probable, or definite VITT-CVT cases included until January 18, 2022. Immunomodulation entailed administration of intravenous immunoglobulins and/or plasmapheresis.Ninety-nine patients with VITT-CVT from 71 hospitals in 17 countries were analyzed. Five of 38 (13%), 11 of 24 (46%), and 28 of 37 (76%) of the patients diagnosed in March, April, and from May onward, respectively, were treated in-line with VITT recommendations (p<0.001). Overall, treatment according to recommendations had no statistically significant influence on mortality (14/44 [32%] vs 29/55 [52%], adjusted odds ratio [OR]=0.43, 95% confidence interval [CI]=0.16-1.19). However, patients who received immunomodulation had lower mortality (19/65 [29%] vs 24/34 [70%], adjusted OR=0.19, 95% CI=0.06-0.58). Treatment with non-heparin anticoagulants instead of heparins was not associated with lower mortality (17/51 [33%] vs 13/35 [37%], adjusted OR=0.70, 95% CI=0.24-2.04). Mortality was also not significantly influenced by platelet transfusion (17/27 [63%] vs 26/72 [36%], adjusted OR=2.19, 95% CI=0.74-6.54).In patients with VITT-CVT, adherence to VITT treatment recommendations improved over time. Immunomodulation seems crucial for reducing mortality of VITT-CVT. ANN NEUROL 2022;92:562-573. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng |
| 653 | a Adenoviridae | |
| 653 | a Anticoagulants | |
| 653 | a therapeutic use | |
| 653 | a COVID-19 | |
| 653 | a COVID-19 Vaccines | |
| 653 | a adverse effects | |
| 653 | a Humans | |
| 653 | a Immunoglobulins | |
| 653 | a Intravenous | |
| 653 | a therapeutic use | |
| 653 | a Intracranial Thrombosis | |
| 653 | a SARS-CoV-2 | |
| 653 | a Vaccination | |
| 653 | a adverse effects | |
| 653 | a Venous Thrombosis | |
| 653 | a complications | |
| 700 | 1 | a Krzywicka, Katarzynau Department of Neurology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a Mbroh, Joshuau Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tuebingen, Germany; Department of Neurology & Stroke, Eberhard-Karls University, Tuebingen, Germany4 aut |
| 700 | 1 | a van de Munckhof, Anitau Department of Neurology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a van Kammen, Mayte Sánchezu Department of Neurology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a de Sousa, Diana Aguiaru CEEM and Institute of Anatomy, Faculty of Medicine, University of Lisbon, Lisbon, Portugal4 aut |
| 700 | 1 | a Lindgren, Erik,d 1993u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Gothenburg, Sweden4 aut0 (Swepub:gu)xliere |
| 700 | 1 | a Jood, Katarina,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Gothenburg, Sweden4 aut0 (Swepub:gu)xjooka |
| 700 | 1 | a Günther, Albrechtu Department of Neurology, Jena University Hospital, Jena, Germany4 aut |
| 700 | 1 | a Hiltunen, Siniu Department of Neurology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Putaala, Jukkau Department of Neurology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Tiede, Andreasu Clinic for Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany4 aut |
| 700 | 1 | a Maier, Franku Department of Neurology, Caritas Hospital Saarbrücken, Saarbrücken, Germany4 aut |
| 700 | 1 | a Kern, Rolfu Department of Neurology, Kempten Hospital, Kempten, Germany4 aut |
| 700 | 1 | a Bartsch, Thorstenu Department of Neurology, University Medical Center Schleswig-Holstein, Kiel, Germany4 aut |
| 700 | 1 | a Althaus, Katharinau Department of Neurology, Ulm University Hospital, Ulm, Germany4 aut |
| 700 | 1 | a Ciccone, Alfonsou Department of Neurology, Carlo Poma Hospital, Azienda Socio Sanitaria Territoriale di Mantova, Mantua, Italy4 aut |
| 700 | 1 | a Wiedmann, Markusu Department of Neurosurgery, Oslo University Hospital, Oslo, Norway4 aut |
| 700 | 1 | a Skjelland, Monau Department of Neurosurgery, Oslo University Hospital, Oslo, Norway4 aut |
| 700 | 1 | a Medina, Antoniou Department of Neurology, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain4 aut |
| 700 | 1 | a Cuadrado-Godia, Elisau Department of Neurology, University Hospital del Mar, Barcelona, Spain4 aut |
| 700 | 1 | a Cox, Thomasu Department of Neurology, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom4 aut |
| 700 | 1 | a Aujayeb, Avinashu Respiratory Department, Northumbria Healthcare NHS Foundation Trust, Cramlington, United Kingdom,Department of Hematology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland,Department of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands4 aut |
| 700 | 1 | a Raposo, Nicolasu Department of Neurology, Toulouse University Hospital, Toulouse, France4 aut |
| 700 | 1 | a Garambois, Katiau Stroke Unit, University Hospital of Grenoble, Grenoble, France4 aut |
| 700 | 1 | a Payen, Jean-Francoisu Stroke Unit, University Hospital of Grenoble, Grenoble, France4 aut |
| 700 | 1 | a Vuillier, Fabriceu Stroke Unit, University Hospital of Besancon, Besancon, France4 aut |
| 700 | 1 | a Franchineau, Guillaumeu Department of Intensive Care, Centre Hospitalier Intercommunal de Poissy Saint Germain en Laye, Poissy, France4 aut |
| 700 | 1 | a Timsit, Sergeu Neurology and Stroke Unit, Centre Hospitalier Universitaire de Brest, CHU Brest, Brest, France4 aut |
| 700 | 1 | a Bougon, Davidu Department of Critical Care, Annecy Genevois Hospital, Annecy, France4 aut |
| 700 | 1 | a Dubois, Marie-Cécileu Department of Anesthesia and Intensive Care, University Hospital of Poitiers, Poitiers, France4 aut |
| 700 | 1 | a Tawa, Audreyu Department of Anesthesia and Intensive Care, University Hospital of Rennes, Rennes, France4 aut |
| 700 | 1 | a Tracol, Clementu Department of Neurology, CHU Rennes, Rennes, France4 aut |
| 700 | 1 | a De Maistre, Emmanuelu Department of Biological Haematology, CHU Dijon, Dijon, France4 aut |
| 700 | 1 | a Bonneville, Fabriceu Department of Neuroradiology, Toulouse University Hospital, Toulouse, France4 aut |
| 700 | 1 | a Vayne, Carolineu Department of Hematology and Hemostasis, Tours University Hospital, Tours, France4 aut |
| 700 | 1 | a Mengel, Anneroseu Department of Neurology and Stroke, Eberhard-Karls University, Tuebingen, Germany4 aut |
| 700 | 1 | a Michalski, Dominiku Department of Neurology, Leipzig University Hospital, Leipzig, Germany4 aut |
| 700 | 1 | a Pelz, Johannu Department of Neurology, Leipzig University Hospital, Leipzig, Germany4 aut |
| 700 | 1 | a Wittstock, Matthiasu Department of Neurology, University Hospital Rostock, Rostock, Germany4 aut |
| 700 | 1 | a Bode, Felixu Department of Neurology, Universitätsklinikum Bonn, Bonn, Germany4 aut |
| 700 | 1 | a Zimmermann, Julianu Department of Neurology, Universitätsklinikum Bonn, Bonn, Germany4 aut |
| 700 | 1 | a Schouten, Judithu Department of Neurology, Rijnstate Hospital Arnhem, Arnhem, Netherlands4 aut |
| 700 | 1 | a Buture, Alinau Acute Stroke Service, Mater Misericordiae University Hospital, Dublin, Ireland4 aut |
| 700 | 1 | a Murphy, Seanu Acute Stroke Service, Mater Misericordiae University Hospital, Dublin, Ireland4 aut |
| 700 | 1 | a Palma, Vincenzou Department of Neuroradiology, Ospedale del Mare, Naples, Italy4 aut |
| 700 | 1 | a Negro, Albertou Department of Neuroradiology, Ospedale del Mare, Naples, Italy4 aut |
| 700 | 1 | a Gutschalk, Alexanderu Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany4 aut |
| 700 | 1 | a Nagel, Simonu Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany4 aut |
| 700 | 1 | a Schoenenberger, Silviau Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany,Department of Neuroradiology, Policlinico di Bari, Bari, Italy,Department of Neurology, Hospital de Cascais Dr José de Almeida, Cascais, Portugal,Division of Neurology, University of British Columbia, Vancouver Stroke Program, BC, Vancouver, Canada4 aut |
| 700 | 1 | a Frisullo, Giovanniu Department of Neurology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy4 aut |
| 700 | 1 | a Zanferrari, Carlau Department of Neurology, Azienda Ospedaliera di Melegnano e della Martesana, Melegnano, Italy4 aut |
| 700 | 1 | a Grillo, Francescou Stroke Unit, Department of Clinical and Experimental Medicine, University Hospital G. Martino, Messina, Italy4 aut |
| 700 | 1 | a Giammello, Fabriziou Translational Molecular Medicine and Surgery, XXXV Cycle, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy4 aut |
| 700 | 1 | a Martin, Mar Morinu Department of Neurology, Hospital Complex of Toledo, Toledo, Spain,Department of Viroscience, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands,Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal,Department of Neurology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a Cervera, Alvarou Department of Neurology, Royal Darwin Hospital, NT, Tiwi, Australia4 aut |
| 700 | 1 | a Burrow, Jimu Department of Neurology, Royal Darwin Hospital, NT, Tiwi, Australia4 aut |
| 700 | 1 | a Esperon, Carlos Garciau Department of Neurology, John Hunter Hospital, NSW, Newcastle, Australia4 aut |
| 700 | 1 | a Chew, Beng Lim Alvinu Department of Neurology, John Hunter Hospital, NSW, Newcastle, Australia4 aut |
| 700 | 1 | a Kleinig, Timothy Ju Department of Neurology, Royal Adelaide Hospital, SA, Adelaide, Australia4 aut |
| 700 | 1 | a Soriano, Cristinau Department of Neurology, Hospital General de Castellón, Castelló, Spain4 aut |
| 700 | 1 | a Zimatore, Domenico S4 aut |
| 700 | 1 | a Petruzzellis, Marcou Department of Neurology, AOU Consorziale Policlinico di Bari, Bari, Italy4 aut |
| 700 | 1 | a Elkady, Ahmedu Department of Neurology, Saudi German Hospital, Jeddah, Saudi Arabia4 aut |
| 700 | 1 | a Miranda, Miguel S4 aut |
| 700 | 1 | a Fernandes, Joãou Department of Neurology, Norra Älvsborgs Länssjukhus, Trollhättan, Sweden4 aut |
| 700 | 1 | a Vogel, Åslög Hellströmu Department of Internal Medicine, Skåne University Hospital, Lund, Sweden4 aut |
| 700 | 1 | a Johansson, Elias,d 1984u Umeå universitet,Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM),Neurovetenskaper4 aut0 (Swepub:umu)elsjon02 |
| 700 | 1 | a Philip, Anemon Puthuppallilu Department of Neurology, Hamilton General Hospital, ON, Hamilton, Canada4 aut |
| 700 | 1 | a Coutts, Shelagh Bu Department of Clinical Neurosciences, Radiology, and Community Health Sciences, Foothills Medical Centre, AB, Calgary, Canada,Division of Neurology, University of Alberta Hospital, AB, Edmonton, Canada4 aut |
| 700 | 1 | a Bal, Simerpreetu Department of Clinical Neurosciences, Radiology, and Community Health Sciences, Foothills Medical Centre, AB, Calgary, Canada4 aut |
| 700 | 1 | a Buck, Brian4 aut |
| 700 | 1 | a Legault, Catherineu Department of Neurology and Neurosurgery, McGill University Health Centre, QC, Montreal, Canada4 aut |
| 700 | 1 | a Blacquiere, Dylanu Division of Neurology, The Ottawa Hospital, ON, Ottawa, Canada4 aut |
| 700 | 1 | a Katzberg, Hans Du Department of Neuromuscular Medicine, Toronto General Hospital, ON, Toronto, Canada4 aut |
| 700 | 1 | a Field, Thalia S4 aut |
| 700 | 1 | a Dizonno, Vanessau Division of Neurology, University of British Columbia, Vancouver Stroke Program, BC, Vancouver, Canada4 aut |
| 700 | 1 | a Gattringer, Thomasu Department of Neurology, Medical University of Graz, Graz, Austria4 aut |
| 700 | 1 | a Jacobi, Christianu Department of Neurology, Nordwest Hospital, Frankfurt am Main, Germany4 aut |
| 700 | 1 | a Devroye, Annemieu Department of Neurology, University Hospitals Leuven, Leuven, Belgium4 aut |
| 700 | 1 | a Lemmens, Robinu Department of Neurology, University Hospitals Leuven, Leuven, Belgium4 aut |
| 700 | 1 | a Kristoffersen, Espen Saxhaugu Department of Neurology, Akershus University Hospital, Lørenskog, Norway4 aut |
| 700 | 1 | a di Poggio, Monica Bandettiniu Department of Neuroscience, Policlinic San Martino Hospital, Genoa, Italy4 aut |
| 700 | 1 | a Ghiasian, Masoudu Department of Neurology, Sina Hospital, Hamadan University of Medical Science, Hamadan, Iran4 aut |
| 700 | 1 | a Karapanayiotides, Theodorosu Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece4 aut |
| 700 | 1 | a Chatterton, Sophieu Department of Neurology, St. Vincent's Hospital, NSW, Sydney, Australia4 aut |
| 700 | 1 | a Wronski, Miriamu Royal North Shore Hospital, NSW, Sydney, Australia4 aut |
| 700 | 1 | a Ng, Karlu Department of Neurology and Clinical Neurophysiology, Royal North Shore Hospital and The University of Sydney, NSW, Sydney, Australia4 aut |
| 700 | 1 | a Kahnis, Robertu Department of Neurology, Vivantes Auguste-Viktoria-Klinikum, Berlin, Germany4 aut |
| 700 | 1 | a Geeraerts, Thomasu Department of Anaesthesiology and Critical Care, University Toulouse 3-Paul-Sabatier, University Hospital of Toulouse, Hôpital Pierre-Paul Riquet, CHU Toulouse-Purpan, Toulouse, France4 aut |
| 700 | 1 | a Reiner, Peggyu Service de neurologie, hôpital Lariboisière Université Paris-7, AP–HP, Paris Cedex 10, France4 aut |
| 700 | 1 | a Cordonnier, Charlotteu University of Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, Lille, France4 aut |
| 700 | 1 | a Middeldorp, Saskiau Department of Internal Medicine & Radboud Institute of Health Sciences (RIHS), Radboud University Medical Center, Nijmegen, Netherlands4 aut |
| 700 | 1 | a Levi, Marcelu National Institute for Health Research University College London Hospitals (UCLH) Biomedical Research Centre, London, United Kingdom; Department of Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a van Gorp, Eric C M4 aut |
| 700 | 1 | a van de Beek, Diederiku Department of Neurology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a Brodard, Justineu Department of Hematology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland4 aut |
| 700 | 1 | a Kremer Hovinga, Johanna A4 aut |
| 700 | 1 | a Kruip, Marieke J H A4 aut |
| 700 | 1 | a Tatlisumak, Turgutu Department of Neurology & Stroke, Eberhard-Karls University, Tuebingen, Germany4 aut |
| 700 | 1 | a Ferro, José M4 aut |
| 700 | 1 | a Coutinho, Jonathan M4 aut |
| 700 | 1 | a Arnold, Marcelu Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland4 aut |
| 700 | 1 | a Poli, Svenu Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tuebingen, Germany; Department of Neurology & Stroke, Eberhard-Karls University, Tuebingen, Germany4 aut |
| 700 | 1 | a Heldner, Mirjam Ru Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland4 aut |
| 710 | 2 | a Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerlandb Department of Neurology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands4 org |
| 773 | 0 | t Annals of neurologyd : Wileyg 92:4, s. 562-573q 92:4<562-573x 1531-8249x 0364-5134 |
| 856 | 4 | u https://doi.org/10.1002/ana.26431y Fulltext |
| 856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:1683226/FULLTEXT02.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/325556 |
| 856 | 4 8 | u https://doi.org/10.1002/ana.26431 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-198052 |
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