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Sökning: WFRF:(Jensen Steen M.) > (2015-2019) > Idiopathic ventricu...

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FältnamnIndikatorerMetadata
00005909naa a2200589 4500
001oai:DiVA.org:umu-200287
003SwePub
008221017s2019 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:d11e84ab-83e5-4425-b02f-43e2c76f6b30
009oai:gup.ub.gu.se/282146
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2002872 URI
0247 a https://doi.org/10.1016/j.jelectrocard.2019.06.0162 DOI
0247 a https://lup.lub.lu.se/record/d11e84ab-83e5-4425-b02f-43e2c76f6b302 URI
0247 a https://gup.ub.gu.se/publication/2821462 URI
040 a (SwePub)umud (SwePub)lud (SwePub)gu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Chaudhry, U.u Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-ucy
2451 0a Idiopathic ventricular fibrillation – Long term prognosis in relation to clinical findings and ECG patterns in a Swedish cohort
264 1a Philadephia :b Churchill Livingstone Inc. Medical Publishers,c 2019
338 a print2 rdacarrier
520 a Background: Idiopathic ventricular fibrillation (IVF) is a rare cause of sudden cardiac arrest which may pose therapeutic and prognostic challenges. To date, the only effective treatment for survivors of cardiac arrest is the insertion of an implantable cardioverter-defibrillator (ICD). We sought to review the long-term outcome of a Swedish cohort with IVF.Methods and results: Fifty patients with IVF diagnosis between 1988 and 2016 (mean age at index 34.3, 56% male), were followed for a median 13.8 years in this retrospective multicenter observational study. No cardiac mortality was reported. 32% (n = 16) of patients had recurrence of ventricular fibrillation or sustained ventricular tachycardia, requiring ICD therapy, at a median time of 1.9 years (range 0.1–20.3) from the index event. Annual incidence rate of ventricular tachyarrhythmia was 3.1%. Abnormal ECG at baseline did not predict appropriate ICD therapy (p = 0.56). During the follow-up period, 14% (n = 7) patients received a cardiac diagnosis. Follow-up genetic testing was low (26%), however did confirm pathogenic mutations in three cases.Conclusion: Idiopathic VF is a rare diagnosis with a relatively good prognosis provided ICD therapy is initiated. Routine clinical follow-up is recommended due to potential late emerging cardiac pathology. ECG changes are common, but have no prognostic value in determining the risk of ventricular arrhythmias recurrence. Screening for genetic diseases has previously been low, and this calls for improvement, especially since cheaper and more comprehensive genetic panels are now readily available.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a ECG abnormalities
653 a Follow-up
653 a Genetic testing
653 a Implantable cardioverter-defibrillator
653 a Sudden cardiac death
653 a Ventricular fibrillation
653 a ECG abnormalities
653 a Follow-up
653 a Genetic testing
653 a Implantable cardioverter-defibrillator
653 a Sudden cardiac death
653 a Ventricular fibrillation
7001 a Platonov, P. G.u Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups4 aut0 (Swepub:lu)kard-ppl
7001 a Rubulis, Aigars,d 1974u Region Västra Götaland, Sahlgrenska University Hospital, Department of Cardiology, Gothenburg, Sweden4 aut0 (Swepub:gu)xrubai
7001 a Bergfeldt, Lennart,d 1950u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xbleny
7001 a Jensen, Steen M.u Umeå University,Umeå universitet,Institutionen för folkhälsa och klinisk medicin4 aut0 (Swepub:umu)stje0001
7001 a Lundin, C.u Lund University,Lunds universitet,Avdelningen för klinisk genetik,Institutionen för laboratoriemedicin,Medicinska fakulteten,Genetiska och epigenetiska studier av barnleukemi,Forskargrupper vid Lunds universitet,Division of Clinical Genetics,Department of Laboratory Medicine,Faculty of Medicine,Genetic and epigenetic studies of pediatric leukemia,Lund University Research Groups4 aut0 (Swepub:lu)klin-clu
7001 a Borgquist, R.u Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,Aarhus University Hospital4 aut0 (Swepub:lu)medf-rbo
7001 a SM, Lundin4 aut
7102 a Kardiologib Sektion II4 org
7730 t Journal of Electrocardiologyd Philadephia : Churchill Livingstone Inc. Medical Publishersg 56, s. 46-51q 56<46-51x 0022-0736x 1532-8430
8564 u http://dx.doi.org/10.1016/j.jelectrocard.2019.06.016y FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-200287
8564 8u https://doi.org/10.1016/j.jelectrocard.2019.06.016
8564 8u https://lup.lub.lu.se/record/d11e84ab-83e5-4425-b02f-43e2c76f6b30
8564 8u https://gup.ub.gu.se/publication/282146

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