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Outcomes of a unifo...
Outcomes of a uniformly active approach to infants born at 22-24 weeks of gestation
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- Söderström, Fanny (författare)
- Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning
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- Normann, Erik (författare)
- Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning
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- Jonsson, Maria, 1966- (författare)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa
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visa fler...
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- Ågren, Johan, 1966- (författare)
- Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning
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visa färre...
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(creator_code:org_t)
- 2021-01-15
- 2021
- Engelska.
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Ingår i: Archives of Disease in Childhood. - : BMJ Publishing Group Ltd. - 1359-2998 .- 1468-2052. ; 106:4, s. 413-417
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- ObjectiveTo determine survival and outcomes in infants born at 22-24 weeks of gestation in a centre with a uniformly active approach to management of extremely preterm infants.Study designSingle-centre retrospective cohort study including infants born 2006-2015. Short-term morbidities assessed included retinopathy of prematurity, necrotising enterocolitis, patent ductus arteriosus, intraventricular haemorrhage, periventricular malacia and bronchopulmonary dysplasia. Neurodevelopmental outcomes assessed included cerebral palsy, visual impairment, hearing impairment and developmental delay.ResultsTotal survival was 64% (143/222), ranging from 52% at 22 weeks to 70% at 24 weeks. Of 133 (93%) children available for follow-up at 2.5 years corrected age, 34% had neurodevelopmental impairment with 11% classified as moderately to severely impaired. Treatment-requiring retinopathy of prematurity, severe bronchopulmonary dysplasia, visual impairment and developmental delay correlated with lower gestational age.ConclusionsA uniformly active approach to all extremely preterm infants results in survival rates that are not distinctly different across the gestational ages of 22-24 weeks and more than 50% survival even in infants at 22 weeks. The majority were unimpaired at 2.5 years, suggesting that such an approach does not result in higher rates of long-term adverse neurological outcome.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Nyckelord
- neonatology
- neurology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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