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A Perspective on th...
A Perspective on the Roles of Adjuvants in Developing Highly Potent COVID-19 Vaccines
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- Zhang, Naru (författare)
- Zhejiang University City College, Hangzhou, China
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- Li, Kangchen (författare)
- Zhejiang University City College, Hangzhou, China
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- Liu, Zezhong (författare)
- Fudan University, Shanghai, China
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- Nandakumar, Kutty Selva, 1965- (författare)
- Karolinska Institute, Stockholm, Sweden
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- Jiang, Shibo (författare)
- Fudan University, Shanghai, China
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(creator_code:org_t)
- 2022-02-14
- 2022
- Engelska.
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Ingår i: Viruses. - : MDPI AG. - 1999-4915. ; 14:2, s. 387-387
- Relaterad länk:
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https://doi.org/10.3...
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https://hh.diva-port... (primary) (Raw object)
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https://www.mdpi.com...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Several countries have made unremitting efforts to develop an optimal vaccine in the fight against coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With the increasing occurrence of SARS-CoV-2 variants, current vaccines show decreased neutralizing activities, especially towards the Omicron variant. In this context, adding appropriate adjuvants to COVID-19 vaccines can substantially reduce the number of required doses and improve efficacy or cross-neutralizing protection. We mainly focus on research progress and achievements associated with adjuvanted COVID-19 subunit and inactivated vaccines. We further compare the advantages and disadvantages of different adjuvant formulations in order to provide a scientific reference for designing an effective strategy for future vaccine development.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
Nyckelord
- COVID-19; SARS-CoV-2; adjuvant; vaccine; variants.
- Health Innovation
- Hälsoinnovation
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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