WFRF:(Semnic Robert)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04243naa a2200457 4500 | |
| 001 | oai:DiVA.org:uu-505306 | |
| 003 | SwePub | |
| 008 | 230619s2023 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5053062 URI |
| 024 | 7 | a https://doi.org/10.1007/s00701-023-05642-22 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Loayza, Richardu Uppsala universitet,Neurokirurgi4 aut |
| 245 | 1 0 | a Outcome after microvascular decompression for trigeminal neuralgia in a single center :b relation to sex and severity of neurovascular conflict |
| 264 | 1 | b Springer Nature,c 2023 |
| 338 | a electronic2 rdacarrier | |
| 520 | a BACKGROUND: Trigeminal neuralgia (TN), a severe type of facial pain, is mainly caused by a neurovascular conflict (NVC). The severity of the NVC seems associated with the outcome following microvascular decompression (MVD) surgery. This study aimed to investigate the outcome after MVD and whether it is affected by NVC severity and sex.METHODS: TN patients (n = 109) were followed for 5 to 10 years after MVD. Barrow Neurology Index (BNI), Patients Global Impression of Change (PGIC), complications, and time to relapse were evaluated. The NVC severity was retrospectively reviewed from presurgical MRI. Demographic and clinical factors and NVC severity were analyzed for potential association with outcome after MVD.RESULTS: The success rate (BNI ≤ 2) was 80% after 5 to 10 years follow-up for TN patients with severe NVC (grade 2-3) and 56% for TN patients with mild NVC (grade 0-1, P = 0.003). No sex difference was observed in outcome for patients with both mild (P = 0.924) and severe NVC (P = 0.883) respectively. Three patients (2.8%) during the hospital stay, and two patients (1.8%) at 6 weeks, experienced a complication requiring invasive treatment. At long-term 52/109 patients (47.7%) reported some type of persistent adverse event, of which the majority were mild and required no treatment.CONCLUSIONS: MVD offers an 80% probability of long-term pain relief in TN patients with severe NVC, with low frequency of serious complications. NVC severity significantly affects outcome after MVD, while no sex differences in outcome were found. In consistency with previous work, the results stress the importance of adequate neuroradiological assessment of the NVC for preoperative patient selection. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
| 653 | a Facial pain | |
| 653 | a Microvascular decompression | |
| 653 | a Neurovascular conflict | |
| 653 | a Trigeminal neuralgia | |
| 700 | 1 | a Wikström, Johan,c Professor,d 1964-u Uppsala universitet,Radiologi,Neuroradiology4 aut0 (Swepub:uu)jwi06759 |
| 700 | 1 | a Grabowska, Annau Uppsala universitet,Radiologi,Neuroradiology4 aut0 (Swepub:uu)anngr420 |
| 700 | 1 | a Semnic, Robertu Uppsala universitet,Radiologi,Neuroradiology4 aut |
| 700 | 1 | a Ericson, Hans,d 1959-u Uppsala universitet,Neurokirurgi4 aut0 (Swepub:uu)hanseric |
| 700 | 1 | a Abu Hamdeh, Samiu Uppsala universitet,Neurokirurgi4 aut0 (Swepub:uu)samab670 |
| 710 | 2 | a Uppsala universitetb Neurokirurgi4 org |
| 773 | 0 | t Acta Neurochirurgicad : Springer Natureg 165:7, s. 1955-1962q 165:7<1955-1962x 0001-6268x 0942-0940 |
| 856 | 4 | u https://doi.org/10.1007/s00701-023-05642-2y Fulltext |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1770292/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-505306 |
| 856 | 4 8 | u https://doi.org/10.1007/s00701-023-05642-2 |
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