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FältnamnIndikatorerMetadata
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001oai:DiVA.org:umu-183573
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008210603s2021 | |||||||||||000 ||eng|
009oai:DiVA.org:su-195590
009oai:DiVA.org:uu-454478
009oai:prod.swepub.kib.ki.se:146519164
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1835732 URI
0247 a https://doi.org/10.1111/apt.163722 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1955902 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4544782 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1465191642 URI
040 a (SwePub)umud (SwePub)sud (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Talley, Nicholas J.u Faculty of Health and Medicine, University of Newcastle, Lot 1 Kookaburra Circuit, New Lambton Heights, Australia; NHMRC Centre for Research Excellence in Digestive Health, Australia,Univ Newcastle, Fac Hlth & Med, Lot 1 Kookaburra Circuit, New Lambton Hts 2305, Australia.;NHMRC Ctr Res Excellence Digest Hlth, New Lambton Hts, NSW, Australia.4 aut
2451 0a Role of smoking in functional dyspepsia and irritable bowel syndrome :b three random population-based studies
264 c 2021-05-13
264 1b John Wiley & Sons,c 2021
338 a print2 rdacarrier
520 a Background: It is uncertain if functional dyspepsia (FD) or irritable bowel syndrome (IBS) are linked to smoking, and smoking cessation is not part of the routine advice provided to these patients.Aim: To assess if smoking is an independent risk factor for FD and IBS.Methods: Three population-based endoscopy studies in Sweden with 2560 community individuals in total (mean age 51.5 years, 46% male). IBS (14.9%), FD (33.5%), and associated symptoms were assessed using the validated abdominal symptom questionnaire, and smoking (17.9%) was obtained from standardised questions during a clinic visit. The effect of smoking on symptom status was analysed in an individual person data meta-analysis using mixed effect logistic regression, adjusted for snuffing, age and sex.Results: Individuals smoking cigarettes reported significantly higher odds of postprandial distress syndrome (FD-PDS) (OR 10-19 cig/day = 1.42, 95% CI 1.04-1.98 P = 0.027, OR ≥20 cig/day = 2.16, 95% CI 1.38-3.38, P = 0.001) but not epigastric pain. Individuals smoking 20 or more cigarettes per day reported significantly higher odds of IBS-diarrhoea (OR = 2.40, 95% CI 1.12-5.16, P = 0.025), diarrhoea (OR = 2.01, 95%CI 1.28-3.16, P = 0.003), urgency (OR = 2.21, 95%CI 1.41-3.47, P = 0.001) and flatus (OR = 1.77, 95%CI 1.14-2.76, P = 0.012) than non-smokers. Smoking was not associated with IBS-constipation or IBS-mixed.Conclusion: Smoking is an important environmental risk factor for postprandial distress syndrome, the most common FD subgroup, with over a twofold increased odds of PDS in heavy smokers. The role of smoking in IBS-diarrhoea, but not constipation, is also likely important.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
7001 a Powell, Nicholasu Division of Digestive Disease, Imperial College, London, United Kingdom,Imperial Coll, Div Digest Dis, London, England.4 aut
7001 a Walker, Marjorie M.u Faculty of Health and Medicine, University of Newcastle, Lot 1 Kookaburra Circuit, New Lambton Heights, Australia; NHMRC Centre for Research Excellence in Digestive Health, Australia,Univ Newcastle, Fac Hlth & Med, Lot 1 Kookaburra Circuit, New Lambton Hts 2305, Australia.;NHMRC Ctr Res Excellence Digest Hlth, New Lambton Hts, NSW, Australia.4 aut
7001 a Jones, Mike P.u NHMRC Centre for Research Excellence in Digestive Health, Australia; Department of Psychology, Macquarie University, NSW, North Ryde, Australia,NHMRC Ctr Res Excellence Digest Hlth, New Lambton Hts, NSW, Australia.;Macquarie Univ, Dept Psychol, N Ryde, NSW, Australia.4 aut
7001 a Ronkainen, Jukkau Center for Life Course Health Research, University of Oulu, Oulu, Finland; Primary Health Care Centre, Tornio, Finland,Univ Oulu, Ctr Life Course Hlth Res, Oulu, Finland.;Primary Hlth Care Ctr, Tornio, Finland.4 aut
7001 a Forsberg, Annau Karolinska Institutet4 aut
7001 a Kjellström, Larsu Gastromottagningen City, Stockholm, Sweden.4 aut
7001 a Hellström, Per M.,d 1954-u Uppsala universitet,Gastroenterologi/hepatologi4 aut0 (Swepub:uu)perhe742
7001 a Aro, Perttiu Arokero OY, Tornio, Finland.4 aut
7001 a Wallner, Bengt,d 1962-u Umeå universitet,Kirurgi,Umeå Univ, Dept Surg & Perioperatve Sci, Umeå, Sweden.4 aut0 (Swepub:umu)bewa0005
7001 a Agréus, Larsu Karolinska Institutet4 aut
7001 a Andreasson, Annau Karolinska Institutet,Stockholms universitet,Stressforskningsinstitutet,Macquarie University, Australia; Karolinska Institutet, Sweden,Macquarie Univ, Dept Psychol, N Ryde, NSW, Australia.;Karolinska Inst, Dept Med Solna, Solna, Sweden.;Stockholm Univ, Stress Res Inst, Dept Psychol, Stockholm, Sweden.4 aut0 (Swepub:su)anan6088
7102 a Faculty of Health and Medicine, University of Newcastle, Lot 1 Kookaburra Circuit, New Lambton Heights, Australia; NHMRC Centre for Research Excellence in Digestive Health, Australiab Univ Newcastle, Fac Hlth & Med, Lot 1 Kookaburra Circuit, New Lambton Hts 2305, Australia.;NHMRC Ctr Res Excellence Digest Hlth, New Lambton Hts, NSW, Australia.4 org
7730 t Alimentary Pharmacology and Therapeuticsd : John Wiley & Sonsg 54:1, s. 32-42q 54:1<32-42x 0269-2813x 1365-2036
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-183573
8564 8u https://doi.org/10.1111/apt.16372
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-195590
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-454478
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:146519164

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