WFRF:(Thompson Julie)
Sökning: WFRF:(Thompson Julie) > (2015-2019) > A genome-wide assoc...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04651naa a2200649 4500 | |
| 001 | oai:lup.lub.lu.se:2aa64163-6feb-45fd-ab89-136e0f912ba9 | |
| 003 | SwePub | |
| 008 | 171026s2017 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/2aa64163-6feb-45fd-ab89-136e0f912ba92 URI |
| 024 | 7 | a https://doi.org/10.1038/leu.2016.2712 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Vijayakrishnan, Jayaramu Institute of Cancer Research London4 aut |
| 245 | 1 0 | a A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1 |
| 264 | c 2016-10-03 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2017 |
| 300 | a 7 s. | |
| 520 | a Genome-wide association studies (GWASs) have shown that common genetic variation contributes to the heritable risk of childhood acute lymphoblastic leukemia (ALL). To identify new susceptibility loci for the largest subtype of ALL, B-cell precursor ALL (BCP-ALL), we conducted a meta-analysis of two GWASs with imputation using 1000 Genomes and UK10K Project data as reference (totaling 1658 cases and 7224 controls). After genotyping an additional 2525 cases and 3575 controls, we identify new susceptibility loci for BCP-ALL mapping to 10q26.13 (rs35837782, LHPP, P=1.38 × 10-11) and 12q23.1 (rs4762284, ELK3, P=8.41 × 10-9). We also provide confirmatory evidence for the existence of independent risk loci at 9p21.3, but show that the association marked by rs77728904 can be accounted for by linkage disequilibrium with the rare high-impact CDKN2A p.Ala148Thr variant rs3731249. Our data provide further insights into genetic susceptibility to ALL and its biology. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
| 700 | 1 | a Kumar, R.u German Cancer Research Centre4 aut0 (Swepub:lu)bioc-rku |
| 700 | 1 | a Henrion, M. Y.R.u Institute of Cancer Research London4 aut |
| 700 | 1 | a Moorman, A Vu University of Newcastle upon Tyne4 aut |
| 700 | 1 | a Rachakonda, P Sivaramakrishnau German Cancer Research Centre4 aut |
| 700 | 1 | a Hosen, Ismailu German Cancer Research Centre4 aut |
| 700 | 1 | a Da Silva Filho, M. I.u German Cancer Research Centre4 aut0 (Swepub:lu)med-md_ |
| 700 | 1 | a Holroyd, Au Institute of Cancer Research London4 aut |
| 700 | 1 | a Dobbins, Sara E.u Institute of Cancer Research London4 aut |
| 700 | 1 | a Koehler, Rolfu Heidelberg University4 aut |
| 700 | 1 | a Thomsen, H.u German Cancer Research Centre4 aut0 (Swepub:lu)med-hth |
| 700 | 1 | a Irving, Julie Au University of Newcastle upon Tyne4 aut |
| 700 | 1 | a Allan, J Mu University of Newcastle upon Tyne4 aut |
| 700 | 1 | a Lightfoot, Tracyu University of York4 aut |
| 700 | 1 | a Roman, Erikau University of York4 aut |
| 700 | 1 | a Kinsey, Sally Eu Leeds General Infirmary4 aut |
| 700 | 1 | a Sheridan, Eamonnu University of Leeds4 aut |
| 700 | 1 | a Thompson, P. D.u University of Manchester4 aut |
| 700 | 1 | a Hoffmann, Pu University of Bonn,University Hospital Basel4 aut |
| 700 | 1 | a Nöthen, M Mu University of Bonn4 aut |
| 700 | 1 | a Heilmann-Heimbach, Stefanieu University of Bonn4 aut |
| 700 | 1 | a Jöckel, Karl-Heinzu University Hospital Essen4 aut |
| 700 | 1 | a Greaves, M. W.u Institute of Cancer Research London4 aut |
| 700 | 1 | a Harrison, C Ju University of Newcastle upon Tyne4 aut |
| 700 | 1 | a Bartram, C Ru Heidelberg University4 aut |
| 700 | 1 | a Schrappe, Martinu University Medical Center Schleswig-Holstein4 aut |
| 700 | 1 | a Stanulla, Martinu Hannover Medical School4 aut |
| 700 | 1 | a Hemminki, K.u Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,German Cancer Research Centre4 aut0 (Swepub:lu)med-khk |
| 700 | 1 | a Houlston, R Su Institute of Cancer Research London4 aut |
| 710 | 2 | a Institute of Cancer Research Londonb German Cancer Research Centre4 org |
| 773 | 0 | t Leukemiad : Springer Science and Business Media LLCg 31:3, s. 573-579q 31:3<573-579x 0887-6924x 1476-5551 |
| 856 | 4 | u http://dx.doi.org/10.1038/leu.2016.271x freey FULLTEXT |
| 856 | 4 | u https://www.nature.com/articles/leu2016271.pdf |
| 856 | 4 8 | u https://lup.lub.lu.se/record/2aa64163-6feb-45fd-ab89-136e0f912ba9 |
| 856 | 4 8 | u https://doi.org/10.1038/leu.2016.271 |
Hitta mer i SwePub
- Av författaren/redakt...
- Vijayakrishnan, ...
- Kumar, R.
- Henrion, M. Y.R.
- Moorman, A V
- Rachakonda, P Si ...
- Hosen, Ismail
- visa fler...
- Da Silva Filho, ...
- Holroyd, A
- Dobbins, Sara E.
- Koehler, Rolf
- Thomsen, H.
- Irving, Julie A
- Allan, J M
- Lightfoot, Tracy
- Roman, Erika
- Kinsey, Sally E
- Sheridan, Eamonn
- Thompson, P. D.
- Hoffmann, P
- Nöthen, M M
- Heilmann-Heimbac ...
- Jöckel, Karl-Hei ...
- Greaves, M. W.
- Harrison, C J
- Bartram, C R
- Schrappe, Martin
- Stanulla, Martin
- Hemminki, K.
- Houlston, R S
- visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Medicinska och f ...
- och Medicinsk geneti ...
- Artiklar i publikationen
- Leukemia
- Av lärosätet
- Lunds universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
