Sökning: WFRF:(Wang Chunliang 1980 ) > (2015-2019) > Changes in brain ar...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 06439naa a2200733 4500 | |
001 | oai:DiVA.org:kth-232773 | |
003 | SwePub | |
008 | 180807s2018 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:uu-355452 | |
009 | oai:prod.swepub.kib.ki.se:138746378 | |
009 | oai:slubar.slu.se:96325 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-2327732 URI |
024 | 7 | a https://doi.org/10.1073/pnas.18010241152 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3554522 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1387463782 URI |
024 | 7 | a https://res.slu.se/id/publ/963252 URI |
040 | a (SwePub)kthd (SwePub)uud (SwePub)kid (SwePub)slu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Brusini, Ireneu KTH,Medicinsk avbildning,KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Huddinge, Sweden4 aut0 (Swepub:kth)u10xcm96 |
245 | 1 0 | a Changes in brain architecture are consistent with altered fear processing in domestic rabbits |
264 | c 2018-06-25 | |
264 | 1 | b National Academy of Sciences,c 2018 |
338 | a print2 rdacarrier | |
500 | a QC 20180807 | |
520 | a The most characteristic feature of domestic animals is their change in behavior associated with selection for tameness. Here we show, using high-resolution brain magnetic resonance imaging in wild and domestic rabbits, that domestication reduced amygdala volume and enlarged medial prefrontal cortex volume, supporting that areas driving fear have lost volume while areas modulating negative affect have gained volume during domestication. In contrast to the localized gray matter alterations, white matter anisotropy was reduced in the corona radiata, corpus callosum, and the subcortical white matter. This suggests a compromised white matter structural integrity in projection and association fibers affecting both afferent and efferent neural flow, consistent with reduced neural processing. We propose that compared with their wild ancestors, domestic rabbits are less fearful and have an attenuated flight response because of these changes in brain architecture. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
650 | 7 | a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe |
650 | 7 | a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng |
650 | 7 | a LANTBRUKSVETENSKAPERx Veterinärmedicinx Medicinsk biovetenskap0 (SwePub)403012 hsv//swe |
650 | 7 | a AGRICULTURAL SCIENCESx Veterinary Sciencex Medical Bioscience0 (SwePub)403012 hsv//eng |
653 | a rabbit | |
653 | a domestication | |
653 | a brain morphology | |
653 | a magnetic resonance imaging | |
653 | a fear | |
700 | 1 | a Carneiro, Miguelu Univ Porto, Ctr Invest Biodiversidade & Recursos Genet CIBIO, InBIO, P-4485661 Vairao, Portugal.;Univ Porto, Dept Biol, Fac Ciencias, P-4169007 Porto, Portugal.4 aut |
700 | 1 | a Wang, Chunliang,d 1980-u KTH,Medicinsk avbildning,KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Huddinge, Sweden4 aut0 (Swepub:kth)u1tbkeej |
700 | 1 | a Rubin, Carl-Johanu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)carub021 |
700 | 1 | a Ring, Henrik,d 1981-u Uppsala universitet,Medicinsk utvecklingsbiologi4 aut0 (Swepub:uu)henri246 |
700 | 1 | a Afonso, Sandrau Univ Porto, Ctr Invest Biodiversidade & Recursos Genet CIBIO, InBIO, P-4485661 Vairao, Portugal.4 aut |
700 | 1 | a Blanco-Aguiar, Jose A.u Univ Porto, Ctr Invest Biodiversidade & Recursos Genet CIBIO, InBIO, P-4485661 Vairao, Portugal.;CSIC, Inst Invest Recursos Cineget IREC, Ciudad Real 13005, Spain.;UCLM, CSIC, Ciudad Real 13005, Spain.4 aut |
700 | 1 | a Ferrand, Nunou Univ Porto, Ctr Invest Biodiversidade & Recursos Genet CIBIO, InBIO, P-4485661 Vairao, Portugal.;Univ Porto, Dept Biol, Fac Ciencias, P-4169007 Porto, Portugal.;Univ Johannesburg, Dept Zool, ZA-2006 Auckland Pk, South Africa.4 aut |
700 | 1 | a Rafati, Nimau Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)nimra236 |
700 | 1 | a Villafuerte, Rafaelu CSIC, IESA, Cordoba 14004, Spain.4 aut |
700 | 1 | a Smedby, Örjan,d 1956-u KTH,Medicinsk avbildning,KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Huddinge, Sweden4 aut0 (Swepub:kth)u1vc2uzb |
700 | 1 | a Damberg, Peteru Karolinska Institutet4 aut |
700 | 1 | a Hallböök, Finn,d 1962-u Uppsala universitet,Medicinsk utvecklingsbiologi4 aut0 (Swepub:uu)finnhb |
700 | 1 | a Fredriksson, Mu Karolinska Institutet,Uppsala universitet,Institutionen för psykologi,Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden4 aut0 (Swepub:uu)matsfred |
700 | 1 | a Andersson, Leifu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab,Texas A&M Univ, Coll Vet Med & Biomed Sci, Dept Vet Integrat Biosci, College Stn, TX USA; Swedish Univ Agr Sci, Dept Anim Breeding & Genet, Uppsala, Sweden,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics,Uppsala University,Texas A&M University4 aut0 (Swepub:slu)48730 |
710 | 2 | a KTHb Medicinsk avbildning4 org |
710 | 2 | a Sveriges lantbruksuniversitet |
773 | 0 | t Proceedings of the National Academy of Sciences of the United States of Americad : National Academy of Sciencesg 115:28, s. 7380-7385q 115:28<7380-7385x 0027-8424x 1091-6490 |
856 | 4 | u https://doi.org/10.1073/pnas.1801024115 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-232773 |
856 | 4 8 | u https://doi.org/10.1073/pnas.1801024115 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-355452 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:138746378 |
856 | 4 8 | u https://res.slu.se/id/publ/96325 |
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