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WFRF:(Willander K.)
 

Sökning: WFRF:(Willander K.) > RETRACTED: Empirica...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004035naa a2200409 4500
001oai:DiVA.org:liu-137629
003SwePub
008170522s2017 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1376292 URI
024a https://doi.org/10.1038/srep466032 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Fakhar-E-Alam, Muhammadu Linköpings universitet,Institutionen för teknik och naturvetenskap,Tekniska fakulteten,University of Elect Science and Technology China, Peoples R China; GC University, Pakistan4 aut
2451 0a RETRACTED: Empirical Modeling of Physiochemical Immune Response of Multilayer Zinc Oxide Nanomaterials under UV Exposure to Melanoma and Foreskin Fibroblasts
264 c 2017-04-24
264 1b NATURE PUBLISHING GROUP,c 2017
338 a print2 rdacarrier
500 a Funding Agencies|Deanship of Scientific Research at King Saud University [RGP-VPP-293]The article is retracted, see retraction notice: https://doi.org/10.1038/s41598-023-40251-0
520 a Carcinogenesis is a complex molecular process starting with genetic and epigenetic alterations, mutation stimulation, and DNA modification, which leads to proteomic adaptation ending with an uncontrolled proliferation mechanism. The current research focused on the empirical modelling of the physiological response of human melanoma cells (FM55P) and human foreskin fibroblasts cells (AG01518) to the multilayer zinc oxide (ZnO) nanomaterials under UV-A exposure. To validate this experimental scheme, multilayer ZnO nanomaterials were grown on a femtotip silver capillary and conjugated with protoporphyrin IX (PpIX). Furthermore, PpIX-conjugated ZnO nanomaterials grown on the probe were inserted into human melanoma (FM55P) and foreskin fibroblasts cells (AG01518) under UV-A light exposure. Interestingly, significant cell necrosis was observed because of a loss in mitochondrial membrane potential just after insertion of the femtotip tool. Intense reactive oxygen species (ROS) fluorescence was observed after exposure to the ZnO NWs conjugated with PpIX femtotip model under UV exposure. Results were verified by applying several experimental techniques, e.g., ROS detection, MTT assay, and fluorescence spectroscopy. The present work reports experimental modelling of cell necrosis in normal human skin as well as a cancerous tissue. These obtained results pave the way for a more rational strategy for biomedical and clinical applications.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng
700a Waseem Akram, M.u University of Elect Science and Technology China, Peoples R China4 aut
700a Iqbal, Seemabu GC University, Pakistan4 aut
700a Alimgeer, K. S.u COMSATS Institute Informat Technology, Pakistan4 aut
700a Atif, M.u King Saud University, Saudi Arabia; National Institute Laser and Optron, Pakistan4 aut
700a Sultana, Kishwaru Linköpings universitet,Institutionen för teknik och naturvetenskap,Tekniska fakulteten4 aut0 (Swepub:liu)kissu79
700a Willander, Magnusu Linköpings universitet,Fysik och elektroteknik,Tekniska fakulteten4 aut0 (Swepub:liu)magwi72
700a Wang, Zhiming M.u University of Elect Science and Technology China, Peoples R China4 aut
710a Linköpings universitetb Institutionen för teknik och naturvetenskap4 org
773t Scientific Reportsd : NATURE PUBLISHING GROUPg 7q 7x 2045-2322
856u https://doi.org/10.1038/s41598-023-40251-0y See retraction note
856u https://www.nature.com/articles/srep46603.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-137629
8564 8u https://doi.org/10.1038/srep46603

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