Sökning: WFRF:(Willander K.) > RETRACTED: Empirica...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 04035naa a2200409 4500 | |
001 | oai:DiVA.org:liu-137629 | |
003 | SwePub | |
008 | 170522s2017 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1376292 URI |
024 | 7 | a https://doi.org/10.1038/srep466032 DOI |
040 | a (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Fakhar-E-Alam, Muhammadu Linköpings universitet,Institutionen för teknik och naturvetenskap,Tekniska fakulteten,University of Elect Science and Technology China, Peoples R China; GC University, Pakistan4 aut |
245 | 1 0 | a RETRACTED: Empirical Modeling of Physiochemical Immune Response of Multilayer Zinc Oxide Nanomaterials under UV Exposure to Melanoma and Foreskin Fibroblasts |
264 | c 2017-04-24 | |
264 | 1 | b NATURE PUBLISHING GROUP,c 2017 |
338 | a print2 rdacarrier | |
500 | a Funding Agencies|Deanship of Scientific Research at King Saud University [RGP-VPP-293]The article is retracted, see retraction notice: https://doi.org/10.1038/s41598-023-40251-0 | |
520 | a Carcinogenesis is a complex molecular process starting with genetic and epigenetic alterations, mutation stimulation, and DNA modification, which leads to proteomic adaptation ending with an uncontrolled proliferation mechanism. The current research focused on the empirical modelling of the physiological response of human melanoma cells (FM55P) and human foreskin fibroblasts cells (AG01518) to the multilayer zinc oxide (ZnO) nanomaterials under UV-A exposure. To validate this experimental scheme, multilayer ZnO nanomaterials were grown on a femtotip silver capillary and conjugated with protoporphyrin IX (PpIX). Furthermore, PpIX-conjugated ZnO nanomaterials grown on the probe were inserted into human melanoma (FM55P) and foreskin fibroblasts cells (AG01518) under UV-A light exposure. Interestingly, significant cell necrosis was observed because of a loss in mitochondrial membrane potential just after insertion of the femtotip tool. Intense reactive oxygen species (ROS) fluorescence was observed after exposure to the ZnO NWs conjugated with PpIX femtotip model under UV exposure. Results were verified by applying several experimental techniques, e.g., ROS detection, MTT assay, and fluorescence spectroscopy. The present work reports experimental modelling of cell necrosis in normal human skin as well as a cancerous tissue. These obtained results pave the way for a more rational strategy for biomedical and clinical applications. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng |
700 | 1 | a Waseem Akram, M.u University of Elect Science and Technology China, Peoples R China4 aut |
700 | 1 | a Iqbal, Seemabu GC University, Pakistan4 aut |
700 | 1 | a Alimgeer, K. S.u COMSATS Institute Informat Technology, Pakistan4 aut |
700 | 1 | a Atif, M.u King Saud University, Saudi Arabia; National Institute Laser and Optron, Pakistan4 aut |
700 | 1 | a Sultana, Kishwaru Linköpings universitet,Institutionen för teknik och naturvetenskap,Tekniska fakulteten4 aut0 (Swepub:liu)kissu79 |
700 | 1 | a Willander, Magnusu Linköpings universitet,Fysik och elektroteknik,Tekniska fakulteten4 aut0 (Swepub:liu)magwi72 |
700 | 1 | a Wang, Zhiming M.u University of Elect Science and Technology China, Peoples R China4 aut |
710 | 2 | a Linköpings universitetb Institutionen för teknik och naturvetenskap4 org |
773 | 0 | t Scientific Reportsd : NATURE PUBLISHING GROUPg 7q 7x 2045-2322 |
856 | 4 | u https://doi.org/10.1038/s41598-023-40251-0y See retraction note |
856 | 4 | u https://www.nature.com/articles/srep46603.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-137629 |
856 | 4 8 | u https://doi.org/10.1038/srep46603 |
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