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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02501naa a2200301 4500 | |
| 001 | oai:DiVA.org:liu-37787 | |
| 003 | SwePub | |
| 008 | 091010s2006 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-377872 URI |
| 024 | 7 | a https://doi.org/10.1186/1476-4598-5-432 DOI |
| 040 | a (SwePub)liu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Sun, Xiao-Feng,d 1959-u Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Onkologi,Onkologiska kliniken US4 aut0 (Swepub:liu)xiasu45 |
| 245 | 1 0 | a Clinicopathological significance of stromal variables :b Angiogenesis, lymphangiogenesis, inflammatory infiltration, MMP and PINCH in colorectal carcinomas |
| 264 | 1 | b Springer Science and Business Media LLC,c 2006 |
| 338 | a print2 rdacarrier | |
| 520 | a Cancer research has mainly focused on alterations of genes and proteins in cancer cells themselves that result in either gain-of-function in oncogenes or loss-of-function in tumour-suppressor genes. However, stromal variables within or around tumours, including blood and lymph vessels, stromal cells and various proteins, have also important impacts on tumour development and progression. It has been shown that disruption of stromal-epithelial interactions influences cellular proliferation, differentiation, death, motility, genomic integrity, angiogenesis, and other phenotypes in various tissues. Moreover, stromal variables are also critical to therapy in cancer patients. In this review, we mainly focus on the clinicopathological significance of stromal variables including angiogenesis, lymphangiogenesis, inflammatory infiltration, matrix metalloproteinase (MMP), and the particularly interesting new cysteine-histidine rich protein (PINCH) in colorectal cancer (CRC). © 2006 Sun and Zhang, licensee BioMed Central Ltd. | |
| 653 | a MEDICINE | |
| 653 | a MEDICIN | |
| 700 | 1 | a Zhang, Hong,d 1957-u Linköpings universitet,Hälsouniversitetet,Avdelningen för dermatologi och venereologi4 aut0 (Swepub:liu)honzh78 |
| 710 | 2 | a Linköpings universitetb Hälsouniversitetet4 org |
| 773 | 0 | t Molecular Cancerd : Springer Science and Business Media LLCg 5q 5x 1476-4598 |
| 856 | 4 | u https://molecular-cancer.biomedcentral.com/track/pdf/10.1186/1476-4598-5-43 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-37787 |
| 856 | 4 8 | u https://doi.org/10.1186/1476-4598-5-43 |
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