Sökning: (WFRF:(Borch Kristin B.)) > Weight change in mi...
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001 | oai:lup.lub.lu.se:4411a3d7-d562-40d9-b506-97c05465ab72 | |
003 | SwePub | |
008 | 201209s2021 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-177088 | |
009 | oai:DiVA.org:uu-438950 | |
024 | 7 | a https://lup.lub.lu.se/record/4411a3d7-d562-40d9-b506-97c05465ab722 URI |
024 | 7 | a https://doi.org/10.1002/ijc.333392 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1770882 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4389502 URI |
040 | a (SwePub)lud (SwePub)umud (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Christakoudi, Sofiau King's College London,Imperial College London,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, St Marys Campus, London W2 1PG, England.;Kings Coll London, MRC Ctr Transplantat, London, England.4 aut |
245 | 1 0 | a Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort |
264 | c 2020-11-09 | |
264 | 1 | b Wiley,c 2021 |
520 | a Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) category during middle adulthood with 42 cancers, using multivariable Cox proportional hazards models in the European Prospective Investigation into Cancer and Nutrition cohort. Of 241 323 participants (31% men), 20% lost and 32% gained weight (>0.4 to 5.0 kg/year) during 6.9 years (average). During 8.0 years of follow-up after the second weight assessment, 20 960 incident cancers were ascertained. Independent of baseline BMI, weight gain (per one kg/year increment) was positively associated with cancer of the corpus uteri (hazard ratio [HR] = 1.14; 95% confidence interval: 1.05-1.23). Compared to stable weight (±0.4 kg/year), weight gain (>0.4 to 5.0 kg/year) was positively associated with cancers of the gallbladder and bile ducts (HR = 1.41; 1.01-1.96), postmenopausal breast (HR = 1.08; 1.00-1.16) and thyroid (HR = 1.40; 1.04-1.90). Compared to maintaining normal weight, maintaining overweight or obese BMI (World Health Organisation categories) was positively associated with most obesity-related cancers. Compared to maintaining the baseline BMI category, weight gain to a higher BMI category was positively associated with cancers of the postmenopausal breast (HR = 1.19; 1.06-1.33), ovary (HR = 1.40; 1.04-1.91), corpus uteri (HR = 1.42; 1.06-1.91), kidney (HR = 1.80; 1.20-2.68) and pancreas in men (HR = 1.81; 1.11-2.95). Losing weight to a lower BMI category, however, was inversely associated with cancers of the corpus uteri (HR = 0.40; 0.23-0.69) and colon (HR = 0.69; 0.52-0.92). Our findings support avoiding weight gain and encouraging weight loss in middle adulthood. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
653 | a BMI change | |
653 | a cancer | |
653 | a middle adulthood | |
653 | a weight gain | |
653 | a weight loss | |
653 | a BMI change | |
700 | 1 | a Pagoni, Panagiotau University of Bristol,University of Ioannina,Univ Ioannina, Dept Hyg & Epidemiol, Sch Med, Ioannina, Greece.;Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, Avon, England.;Univ Bristol, Bristol Med Sch, Populat Hlth Sci, Bristol, Avon, England.4 aut |
700 | 1 | a Ferrari, Pietrou International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, Lyon, France.4 aut |
700 | 1 | a Cross, Amanda J.u Imperial College London,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, St Marys Campus, London W2 1PG, England.4 aut |
700 | 1 | a Tzoulaki, Ioannau Imperial College London,University of Ioannina,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, St Marys Campus, London W2 1PG, England.;Univ Ioannina, Dept Hyg & Epidemiol, Sch Med, Ioannina, Greece.4 aut |
700 | 1 | a Muller, David C.u Imperial College London,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, St Marys Campus, London W2 1PG, England.4 aut |
700 | 1 | a Weiderpass, Elisabeteu International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, Lyon, France.4 aut |
700 | 1 | a Freisling, Heinzu International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, Lyon, France.4 aut |
700 | 1 | a Murphy, Neilu International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, Lyon, France.4 aut |
700 | 1 | a Dossus, Laureu International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, Lyon, France.4 aut |
700 | 1 | a Turzanski Fortner, Reneeu German Cancer Research Centre,German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany.4 aut |
700 | 1 | a Agudo, Antoniou IDIBELL LHospitalet de Llobregat, Unit Nutr & Canc, Canc Epidemiol Res Program, Catalan Inst Oncol, Barcelona, Spain.,Catalan Institute of Oncology4 aut |
700 | 1 | a Overvad, Kimu Aarhus University,Aalborg University Hospital,Aarhus Univ, Dept Publ Hlth, Aarhus, Denmark.;Aalborg Univ Hosp, Dept Cardiol, Aalborg, Denmark.4 aut |
700 | 1 | a Perez-Cornago, Aurorau University of Oxford,Univ Oxford, Nuffield Dept Populat Hlth, Canc Epidemiol Unit, Oxford, England.4 aut |
700 | 1 | a Key, Timothy J.u University of Oxford,Univ Oxford, Nuffield Dept Populat Hlth, Canc Epidemiol Unit, Oxford, England.4 aut |
700 | 1 | a Brennan, Paulu International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, Lyon, France.4 aut |
700 | 1 | a Johansson, Mattiasu International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, Lyon, France.4 aut |
700 | 1 | a Tjønneland, Anneu Danish Cancer Society,Danish Canc Soc Res Ctr, Copenhagen, Denmark.4 aut |
700 | 1 | a Halkjær, Jytteu Danish Cancer Society,Danish Canc Soc Res Ctr, Copenhagen, Denmark.4 aut |
700 | 1 | a Boutron-Ruault, Marie Christineu University of Paris-Saclay,Univ Paris Sud, Univ Paris Saclay, Equipe Exposome Heredite Canc & Sante, INSERM,UVSQ,CESP Gustave Roussy, Villejuif, France.4 aut |
700 | 1 | a Artaud, Fannyu University of Paris-Saclay,Univ Paris Sud, Univ Paris Saclay, Equipe Exposome Heredite Canc & Sante, INSERM,UVSQ,CESP Gustave Roussy, Villejuif, France.4 aut |
700 | 1 | a Severi, Gianlucau University of Paris-Saclay,University of Florence,Univ Paris Sud, Univ Paris Saclay, Equipe Exposome Heredite Canc & Sante, INSERM,UVSQ,CESP Gustave Roussy, Villejuif, France.;Univ Florence, Dept Stat Comp Sci & Applicat G Parenti DISIA, Florence, Italy.4 aut |
700 | 1 | a Kaaks, Rudolfu German Cancer Research Centre,German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany.4 aut |
700 | 1 | a Schulze, Matthias B.u University of Potsdam,German Institute of Human Nutrition,German Inst Human Nutr Potsdam Rehbrucke, Dept Mol Epidemiol, Nuthetal, Germany.;Univ Potsdam, Inst Nutr Sci, Nuthetal, Germany.4 aut |
700 | 1 | a Bergmann, Manuela M.u German Institute of Human Nutrition,German Inst Human Nutr Potsdam Rehbrucke DIfE, Dept Epidemiol, Nuthetal, Germany.4 aut |
700 | 1 | a Masala, Giovannau Institute for Cancer Research, Prevention and Clinical Network (ISPRO),ISPRO, Canc Risk Factors & Life Style Epidemiol Unit, Inst Canc Res Prevent & Clin Network, Florence, Italy.4 aut |
700 | 1 | a Grioni, Sarau Istituto Nazionale dei Tumori,Fdn IRCCS Ist Nazl Tumori Milano, Epidemiol & Prevent Unit, Milan, Italy.4 aut |
700 | 1 | a Simeon, Vittoriou University of Campania Luigi Vanvitelli,Univ LVanvitelli, Dept Mental Phys Hlth & Prevent Med, Naples, Italy.4 aut |
700 | 1 | a Tumino, Rosariou Provincial Health Authority (ASP) Ragusa,Prov Hlth Author ASP Ragusa, Canc Registry & Histopathol Dept, Ragusa, Italy.4 aut |
700 | 1 | a Sacerdote, Carlottau Citta' della Salute e della Scienza Hospital-University of Turin,Citta Salute & Sci Univ Hosp, Unit Canc Epidemiol, Turin, Italy.;Ctr Canc Prevent CPO, Turin, Italy.4 aut |
700 | 1 | a Skeie, Guriu UiT The Arctic University of Norway, Tromsø,UiT Arctic Univ Norway, Dept Community Med, Tromso, Norway.4 aut |
700 | 1 | a Rylander, Charlottau UiT The Arctic University of Norway, Tromsø,UiT Arctic Univ Norway, Dept Community Med, Tromso, Norway.4 aut |
700 | 1 | a Borch, Kristin Benjaminsenu UiT The Arctic University of Norway, Tromsø,UiT Arctic Univ Norway, Dept Community Med, Tromso, Norway.4 aut |
700 | 1 | a Quirós, J. Ramónu Publ Hlth Directorate, Asturias, Spain.4 aut |
700 | 1 | a Rodriguez-Barranco, Miguelu Andalusian School Of Public Health (EASP),CIBER Epidemiology and Public Health (CIBERESP),Escuela Andaluza Salud Publ EASP, Granada, Spain.;Inst Invest Biosanitaria ibs GRANADA, Granada, Spain.;Ctr Invest Biomed Red Epidemiol & Salud Publ CIBE, Madrid, Spain.4 aut |
700 | 1 | a Chirlaque, Maria Doloresu CIBER Epidemiology and Public Health (CIBERESP),University of Murcia,Murcia Regional Health Council,Ctr Invest Biomed Red Epidemiol & Salud Publ CIBE, Madrid, Spain.;IMIB Arrixaca, Reg Hlth Council, Dept Epidemiol, Murcia, Spain.;Univ Murcia, Dept Hlth & Social Sci, Murcia, Spain.4 aut |
700 | 1 | a Ardanaz, Evau CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA),Ctr Invest Biomed Red Epidemiol & Salud Publ CIBE, Madrid, Spain.;Navarra Publ Hlth Inst, Pamplona, Spain.;Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain.4 aut0 (Swepub:lu)extLU-05 |
700 | 1 | a Amiano, Pilaru CIBER Epidemiology and Public Health (CIBERESP),Biodonostia Health Research Institute,Ctr Invest Biomed Red Epidemiol & Salud Publ CIBE, Madrid, Spain.;BioDonostia Researach Inst, Publ Hlth Div Gipuzkoa, San Sebastian, Spain.4 aut |
700 | 1 | a Drake, Isabelu Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Diabetes - Cardiovascular Disease,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Lund Univ, Dept Clin Sci Malmö, Malmö, Sweden.4 aut0 (Swepub:lu)med-ihm |
700 | 1 | a Stocks, Tanjau Lund University,Lunds universitet,Registerbaserad epidemiologi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Register-based epidemiology,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Lund Univ, Dept Clin Sci Lund, Lund, Sweden.4 aut0 (Swepub:lu)med-tss |
700 | 1 | a Häggström, Christelu Uppsala universitet,Umeå universitet,Uppsala University,Umeå University,Enheten för biobanksforskning,Department of Surgical Science, Uppsala University, Uppsala, Sweden,Endokrinkirurgi,Umeå Univ, Dept Biobank Res, Umeå, Sweden.4 aut0 (Swepub:uu)chrha650 |
700 | 1 | a Harlid, Sophiau Umeå universitet,Umeå University,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå, Sweden.4 aut0 (Swepub:umu)soha0105 |
700 | 1 | a Ellingjord-Dale, Mereteu Imperial College London,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, St Marys Campus, London W2 1PG, England.4 aut |
700 | 1 | a Riboli, Eliou Imperial College London,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, St Marys Campus, London W2 1PG, England.4 aut |
700 | 1 | a Tsilidis, Konstantinos K.u University of Ioannina,Imperial College London,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, St Marys Campus, London W2 1PG, England.;Univ Ioannina, Dept Hyg & Epidemiol, Sch Med, Ioannina, Greece.4 aut |
710 | 2 | a King's College Londonb Imperial College London4 org |
773 | 0 | t International Journal of Cancerd : Wileyg 148:7, s. 1637-1651q 148:7<1637-1651x 0020-7136x 1097-0215 |
856 | 4 | u http://dx.doi.org/10.1002/ijc.33339x freey FULLTEXT |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.33339 |
856 | 4 | u https://doi.org/10.1002/ijc.33339y Fulltext |
856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:1505739/FULLTEXT02.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1540536/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://lup.lub.lu.se/record/4411a3d7-d562-40d9-b506-97c05465ab72 |
856 | 4 8 | u https://doi.org/10.1002/ijc.33339 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177088 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-438950 |
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