Search: (WFRF:(Holm Mathias)) pers:(Janson Christer) >
Asthma and treatmen...
Asthma and treatment with inhaled corticosteroids: associations with hospitalisations with pneumonia
-
- Ekbom, Emil (author)
- Uppsala universitet,Lung- allergi- och sömnforskning
-
Quint, J. (author)
-
- Schiöler, Linus, 1977 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
-
show more...
-
- Malinovschi, Andrei, 1978- (author)
- Uppsala universitet,Klinisk fysiologi
-
- Franklin, Karl A (author)
- Umeå universitet,Kirurgi
-
- Holm, Mathias, 1969 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
-
- Torén, Kjell, 1952 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
-
- Lindberg, Eva (author)
- Uppsala universitet,Lung- allergi- och sömnforskning
-
Jarvis, D. (author)
-
- Janson, Christer (author)
- Uppsala universitet,Lung- allergi- och sömnforskning,Population Health and Occupational Disease, National Heart and Lung Institute, Imperial College, London, UK
-
show less...
-
(creator_code:org_t)
- 2019-12-19
- 2019
- English.
-
In: Bmc Pulmonary Medicine. - : Springer Science and Business Media LLC. - 1471-2466. ; 19:1
- Related links:
-
https://bmcpulmmed.b...
-
show more...
-
https://doi.org/10.1...
-
https://umu.diva-por... (primary) (Raw object)
-
https://uu.diva-port... (primary) (Raw object)
-
https://gup.ub.gu.se...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
https://urn.kb.se/re...
-
show less...
Abstract
Subject headings
Close
- Background: Pneumonia is an important cause of morbidity and mortality. COPD patients using inhaled corticosteroids (ICS) have an increased risk of pneumonia, but less is known about whether ICS treatment in asthma also increases the risk of pneumonia. The aim of this analysis was to examine risk factors for hospitalisations with pneumonia in a general population sample with special emphasis on asthma and the use of ICS in asthmatics. Methods: In 1999 to 2000, 7340 subjects aged 28 to 54 years from three Swedish centres completed a brief health questionnaire. This was linked to information on hospitalisations with pneumonia from 2000 to 2010 and treatment with ICS from 2005 to 2010 held within the Swedish National Patient Register and the Swedish Prescribed Drug Register. Results: Participants with asthma (n = 587) were more likely to be hospitalised with pneumonia than participants without asthma (Hazard Ratio (HR 3.35 (1.97-5.02)). Other risk factors for pneumonia were smoking (HR 1.93 (1.22-3.06)), BMI < 20 kg/m(2) (HR 2.74 (1.41-5.36)) or BMI > 30 kg/m(2) (HR 2.54 (1.39-4.67)). Asthmatics (n = 586) taking continuous treatment with fluticasone propionate were at an increased risk of being hospitalized with pneumonia (incidence risk ratio (IRR) 7.92 (2.32-27.0) compared to asthmatics that had not used fluticasone propionate, whereas no significant association was found with the use of budesonide (IRR 1.23 (0.36-4.20)). Conclusion: Having asthma is associated with a three times higher risk of being hospitalised for pneumonia. This analysis also indicates that there are intraclass differences between ICS compounds with respect to pneumonia risk, with an increased risk of pneumonia related to fluticasone propionate.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Keyword
- community-acquired pneumonia
- nocturnal gastroesophageal-reflux
- epidemiologic register
- passive smoking
- risk
- copd
- management
- population
- mortality
- children
- Respiratory System
- Pneumonia
- Lung Medicine
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Ekbom, Emil
-
Quint, J.
-
Schiöler, Linus, ...
-
Malinovschi, And ...
-
Franklin, Karl A
-
Holm, Mathias, 1 ...
-
show more...
-
Torén, Kjell, 19 ...
-
Lindberg, Eva
-
Jarvis, D.
-
Janson, Christer
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Respiratory Medi ...
- Articles in the publication
-
Bmc Pulmonary Me ...
- By the university
-
University of Gothenburg
-
Umeå University
-
Uppsala University