Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort

Fish is a source of important nutrients and may play a role in preventing heart diseases and other health outcomes. However, studies of overall mortality and cause-specific mortality related to fish consumption are inconclusive. We examined the rate of overall mortality, as well as mortality from ischaemic heart disease and cancer in relation to the intake of total fish, lean fish, and fatty fish in a large prospective cohort including ten European countries. More than 500,000 men and women completed a dietary questionnaire in 1992-1999 and were followed up for mortality until the end of 2010. 32,587 persons were reported dead since enrolment. Hazard ratios and their 99 % confidence interval were estimated using Cox proportional hazard regression models. Fish consumption was examined using quintiles based on reported consumption, using moderate fish consumption (third quintile) as reference, and as continuous variables, using increments of 10 g/day. All analyses were adjusted for possible confounders. No association was seen for fish consumption and overall or cause-specific mortality for both the categorical and the continuous analyses, but there seemed to be a U-shaped trend (p < 0.000) with fatty fish consumption and total mortality and with total fish consumption and cancer mortality (p = 0.046).

Braaten, Tonje (author)
Teucher, Birgit (author)
Kuhn, Tilman (author)
Bueno-de-Mesquita, H. B. (author)
Leenders, Max (author)
Agudo, Antonio (author)
Bergmann, Manuela M. (author)
Valanou, Elisavet (author)
Naska, Androniki (author)
Trichopoulou, Antonia (author)
Key, Timothy J. (author)
Crowe, Francesca L. (author)
Overvad, Kim (author)
Sonestedt, EmilyLund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups(Swepub:lu)medf-eso (author)
Mattiello, Amalia (author)
Peeters, Petra H. (author)
Wennberg, MariaUmeå universitet,Näringsforskning(Swepub:umu)mawe0024 (author)
Jansson, Jan HåkanUmeå universitet,Medicin(Swepub:umu)jaja0006 (author)
Boutron-Ruault, Marie-Christine (author)
Dossus, Laure (author)
Dartois, Laureen (author)
Li, Kuanrong (author)
Barricarte, Aurelio (author)
Ward, Heather (author)
Riboli, Elio (author)
Agnoli, Claudia (author)
Maria Huerta, Jose (author)
Sanchez, Maria-Jose (author)
Tumino, Rosario (author)
Altzibar, Jone M. (author)
Vineis, Paolo (author)
Masala, Giovanna (author)
Ferrari, Pietro (author)
Muller, David C. (author)
Johansson, Mattias (author)
Luisa Redondo, M. (author)
Tjonneland, Anne (author)
Olsen, Anja (author)
Olsen, Karina Standahl (author)
Brustad, Magritt (author)
Skeie, Guri (author)
Lund, Eiliv (author)
Diabetes - kardiovaskulär sjukdomForskargrupper vid Lunds universitet (creator_code:org_t)

In:European Journal of Epidemiology: Springer Science and Business Media LLC30:1, s. 57-701573-72840393-2990

By the author/editor: Engeset, Dagrun; Braaten, Tonje; Teucher, Birgit; Kuhn, Tilman; Bueno-de-Mesquit ...; Leenders, Max; show more...; Agudo, Antonio; Bergmann, Manuel ...; Valanou, Elisave ...; Naska, Androniki; Trichopoulou, An ...; Key, Timothy J.; Crowe, Francesca ...; Overvad, Kim; Sonestedt, Emily; Mattiello, Amali ...; Peeters, Petra H ...; Wennberg, Maria; Jansson, Jan Håk ...; Boutron-Ruault, ...; Dossus, Laure; Dartois, Laureen; Li, Kuanrong; Barricarte, Aure ...; Ward, Heather; Riboli, Elio; Agnoli, Claudia; Maria Huerta, Jo ...; Sanchez, Maria-J ...; Tumino, Rosario; Altzibar, Jone M ...; Vineis, Paolo; Masala, Giovanna; Ferrari, Pietro; Muller, David C.; Johansson, Matti ...; Luisa Redondo, M ...; Tjonneland, Anne; Olsen, Anja; Olsen, Karina St ...; Brustad, Magritt; Skeie, Guri; Lund, Eiliv; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Public Health Gl ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Occupational Hea ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Nutrition and Di ...

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