Sökning: (swepub) lar1:(oru) pers:(Tysk Curt) conttype:(refereed) > (2010-2014) > Increased prevalenc...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 06175naa a2200877 4500 | |
001 | oai:DiVA.org:oru-33885 | |
003 | SwePub | |
008 | 140221s2013 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:uu-187166 | |
009 | oai:DiVA.org:liu-89740 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-338852 URI |
024 | 7 | a https://doi.org/10.1097/MPG.0b013e318272cbf42 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1871662 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-897402 URI |
040 | a (SwePub)orud (SwePub)uud (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Stenberg, Reidun,d 1954-u Örebro universitet,Institutionen för hälsovetenskap och medicin,Region Örebro län,Dept of Paediatrics, Centre for Rehabilitation Research, Örebro University Hospital,,Örebro University Hospital, Sweden4 aut0 (Swepub:oru)rsg |
245 | 1 0 | a Increased prevalence of antibodies against dietary proteins in children and young adults with cerebral palsy |
264 | 1 | b Lippincott, Williams and Wilkins,c 2013 |
338 | a print2 rdacarrier | |
500 | a Funding agencies are:Research Committee of Orebro County Council Folke Bernadotte Foundation, Stockholm, Sweden | |
500 | a Funding Agencies|Research Committee of Orebro County Council||Folke Bernadotte Foundation, Stockholm, Sweden|| | |
520 | a OBJECTIVES: Undernourishment is common in children with cerebral palsy (CP), but the reasons are unknown. We previously reported elevated levels of immunoglobulin (Ig) A and IgG antibodies against gliadin (AGA) and tissue transglutaminase (tTG) in 99 children and young adults with CP without characteristic findings of gluten enteropathy in small bowel biopsies. Our aim was to perform a case-control study of IgG antibodies against other dietary antigens, AGA, anti-tTG, and IgE antibodies against wheat and gluten.METHODS: Sera from 99 cases with CP and 99 healthy, age- and sex-matched controls were analysed with fluorescence enzyme-linked immunosorbent assay for detection of IgG antibodies against β-lactoglobulin, casein, egg white, IgG- and IgA-AGA, IgA-anti-tTG, and IgE antibodies against gluten and wheat.RESULTS: Compared with controls, the odds ratio in cases with CP for having elevated levels of IgG antibodies against β-lactoglobulin was 17.0 (95% confidence interval [CI] 2.3-128), against casein 11.0 (95% CI 2.6-46.8), and against egg white 7.0 (95% CI 1.6-30.8). The IgE responses for wheat/gluten were generally low. The tetraplegic and dyskinetic CP subtypes had significantly higher frequencies of elevated levels for all of the tested antibodies except IgG against egg white, and IgA-anti-tTG. A significantly lower weight was seen in cases with CP with positive versus negative serology.CONCLUSIONS: Elevated levels of IgG against dietary antigens were more frequent in the CP group compared with controls, and particularly in the tetraplegic and dyskinetic CP subtypes with the most severe neurologic handicap and undernourishment. Hypothetically, malnourishment may cause increased intestinal permeability and thus immunization against dietary antigens. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
653 | a Adolescent | |
653 | a Adult | |
653 | a Antibodies | |
653 | a Autoantibodies | |
653 | a Body Weight | |
653 | a Case-Control Studies | |
653 | a Caseins | |
653 | a Celiac Disease | |
653 | a Cerebral Palsy | |
653 | a Child | |
653 | a Child | |
653 | a Preschool | |
653 | a Dietary Proteins | |
653 | a Egg White | |
653 | a Female | |
653 | a Glutens | |
653 | a Humans | |
653 | a Immunoglobulin A | |
653 | a Immunoglobulin E | |
653 | a Immunoglobulin G | |
653 | a Infant | |
653 | a Lactoglobulins | |
653 | a Male | |
653 | a Malnutrition | |
653 | a Transglutaminases | |
653 | a Triticum | |
653 | a Young Adult | |
653 | a Invärtesmedicin | |
653 | a Internal Medicine | |
653 | a Pediatrik | |
653 | a Pediatrics | |
653 | a Nutrition | |
653 | a Näringslära | |
653 | a MEDICINE | |
700 | 1 | a Dahle, Charlotteu Östergötlands Läns Landsting,Linköpings universitet,Klinisk immunologi,Hälsouniversitetet,Klinisk immunologi och transfusionsmedicin4 aut0 (Swepub:liu)chada46 |
700 | 1 | a Magnuson, Andersu Clinical Epidemiology and Biostatistic Unit, Örebro University Hospital, Örebro, Sweden4 aut |
700 | 1 | a Hellberg, Dan,d 1953-u Uppsala universitet,Centrum för klinisk forskning Dalarna,Obstetrik & gynekologi,Reproduktiv hälsa/Sundström Poromaa,Clin Research Centre, Sweden4 aut0 (Swepub:uu)dahel227 |
700 | 1 | a Tysk, Curtu Örebro universitet,Institutionen för hälsovetenskap och medicin,Department of Medicine, Örebro University Hospital, Region Örebro County, Örebro, Sweden,Department of Medicine, Division of Gastroenterology, Örebro University Hospital4 aut0 (Swepub:oru)ctk |
710 | 2 | a Örebro universitetb Institutionen för hälsovetenskap och medicin4 org |
773 | 0 | t Journal of Pediatric Gastroenterology and Nutrition - JPGNd : Lippincott, Williams and Wilkinsg 56:2, s. 233-8q 56:2<233-8x 0277-2116x 1536-4801 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-33885 |
856 | 4 8 | u https://doi.org/10.1097/MPG.0b013e318272cbf4 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-187166 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-89740 |
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