L773:1872 7506 OR L773:0925 4927
Sökning: L773:1872 7506 OR L773:0925 4927 > Autonomic modulatio...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03730naa a2200433 4500 | |
| 001 | oai:DiVA.org:uu-418822 | |
| 003 | SwePub | |
| 008 | 200904s2020 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4188222 URI |
| 024 | 7 | a https://doi.org/10.1016/j.pscychresns.2020.1110792 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Bengtsson, Johanu Uppsala universitet,Ekselius: Psykiatri4 aut0 (Swepub:uu)johbe715 |
| 245 | 1 0 | a Autonomic modulation networks in schizophrenia :b The relationship between heart rate variability and functional and structural connectivity in the brain |
| 264 | 1 | b Elsevier BV,c 2020 |
| 338 | a print2 rdacarrier | |
| 520 | a Heart rate variability (HRV), a measurement of autonomic nervous system (ANS) activity, has been found reduced in schizophrenia. The anterior cingulate cortex (ACC), which is important in regulating the ANS, is structurally and functionally affected in schizophrenia. We investigate the relationship between HRV and functional and structural connectivity of the ACC in patients with schizophrenia and healthy controls. Ten patients with a diagnosis of schizophrenia and ten healthy controls were recruited. Heart rate was monitored in a naturalistic out-of-clinic setting. Magnetic resonance imaging (MRI) was performed, including resting-state functional MRI and diffusion tensor imaging. Patients with schizophrenia had significantly lower HRV compared to controls. A positive correlation between ACC connectivity with the bilateral cerebellum and HRV was found in the patients. HRV was also positively correlated with amplitude of low frequency fluctuations (ALFF) in the cerebellum, and with axial diffusivity in the middle cerebellar peduncle, in the patients. There was a significant negative relationship between antipsychotic medication dosage, HRV and all neuroimaging measures related to HRV. We conclude that ACC connectivity seems to be affected in schizophrenia, both structurally and functionally, and that the ACC-cerebellum connectivity, as well as cerebellar function, is associated with ANS regulation in patients with schizophrenia. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng |
| 653 | a ACC | |
| 653 | a Cerebellum | |
| 653 | a HRV | |
| 653 | a MRI | |
| 653 | a Psychotic disorder | |
| 653 | a Resting state | |
| 700 | 1 | a Bodén, Robert,d 1973-u Uppsala universitet,Ekselius: Psykiatri4 aut0 (Swepub:uu)robod677 |
| 700 | 1 | a Olsson, Erik,d 1967-u Uppsala universitet,Klinisk psykologi i hälso- och sjukvård4 aut0 (Swepub:uu)erols031 |
| 700 | 1 | a Mårtensson, Johannau Uppsala universitet,Radiologi,Department of Medical Physics, Uppsala University Hospital4 aut0 (Swepub:uu)johma772 |
| 700 | 1 | a Gingnell, Malin,d 1982-u Uppsala universitet,Ekselius: Psykiatri4 aut0 (Swepub:uu)malgi638 |
| 700 | 1 | a Persson, Jonas,d 1983-u Uppsala universitet,Ekselius: Psykiatri4 aut0 (Swepub:uu)jonpe389 |
| 710 | 2 | a Uppsala universitetb Ekselius: Psykiatri4 org |
| 773 | 0 | t Psychiatry Researchd : Elsevier BVg 300q 300x 0925-4927x 1872-7506 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-418822 |
| 856 | 4 8 | u https://doi.org/10.1016/j.pscychresns.2020.111079 |
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