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Acromegaly manageme...
Acromegaly management in the Nordic countries: A Delphi consensus survey
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- Arlien-Soborg, Mai C. (författare)
- Aarhus Univ Hosp, Denmark,Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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- Dal, Jakob (författare)
- Aalborg Univ Hosp, Denmark; Steno Diabet Ctr North Jutland, Denmark,Department of Endocrinology, Aalborg University Hospital, Aarhus, Denmark; Steno Diabetes Center North Jutland, Aalborg, Denmark
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- Heck, Ansgar (författare)
- Oslo Univ Hosp, Norway,Oslo University Hospital, Oslo, Norway
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visa fler...
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- Stochholm, Kirstine (författare)
- Aarhus Univ Hosp, Denmark,Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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- Husted, Eigil (författare)
- Aalborg Univ Hosp, Denmark,Department of Endocrinology, Aalborg University Hospital, Aarhus, Denmark
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- Feltoft, Claus Larsen (författare)
- Copenhagen Univ Hosp Herlev & Gentofte, Denmark,Copenhagen University Hospital—Herlev and Gentofte, Kobenhavn, Denmark
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- Rasmussen, ase Krogh (författare)
- Copenhagen Univ Hosp, Denmark,Copenhagen University Hospital, Kobenhavn, Denmark
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- Feldt-Rasmussen, Ulla (författare)
- Copenhagen Univ Hosp, Denmark,Copenhagen University Hospital, Kobenhavn, Denmark
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- Andreassen, Mikkel (författare)
- Copenhagen Univ Hosp, Denmark,Copenhagen University Hospital, Kobenhavn, Denmark
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- Klose, Marianne Christina (författare)
- Copenhagen Univ Hosp, Denmark,Copenhagen University Hospital, Kobenhavn, Denmark
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- Nielsen, Torben Leo (författare)
- Odense Univ Hosp, Denmark,Odense University Hospital, Odense, Denmark
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- Andersen, Marianne Skovsager (författare)
- Odense Univ Hosp, Denmark,Odense University Hospital, Odense, Denmark
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- Christensen, Louise Lehmann (författare)
- Odense Univ Hosp, Denmark,Odense University Hospital, Odense, Denmark
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- Krogh, Jesper (författare)
- Copenhagen Univ Hosp, Denmark,Copenhagen University Hospital, Kobenhavn, Denmark
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- Jarlov, Anne (författare)
- Copenhagen Univ Hosp, Denmark,Copenhagen University Hospital, Kobenhavn, Denmark
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- Bollerslev, Jens (författare)
- Oslo Univ Hosp, Norway,Oslo University Hospital, Oslo, Norway
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- Nermoen, Ingrid (författare)
- Akershus Univ Hosp, Norway,Akershus University Hospital, lørenskog, Norway
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- Oksnes, Marianne (författare)
- Haukeland Hosp, Norway,Haukeland University Hospital, Bergen, Norway
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- Dahlqvist, Per (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Norrlands University Hospital, Umeå, Sweden
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- Olsson, Tommy (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Norrlands University Hospital, Umeå, Sweden
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- Berinder, Katarina (författare)
- Karolinska Univ Hosp, Sweden,Karolinska University Hospital, Sweden
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- Hoybye, Charlotte (författare)
- Karolinska Univ Hosp, Sweden,Karolinska University Hospital, Sweden
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- Petersson, Maria (författare)
- Karolinska Univ Hosp, Sweden,Karolinska University Hospital, Sweden
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- Akerman, Anna-karin (författare)
- Orebro Univ, Sweden,School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Sweden; Department of Medicine, Örebro University Hospital, Örebro, Sweden
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- Wahlberg, Jeanette (författare)
- Orebro Univ Hosp, Sweden,Department of Medicine, Örebro University Hospital, Örebro, Sweden
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- Ekman, Bertil (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Medicinkliniken ViN,Region Östergötland, Endokrinmedicinska kliniken,Department of Endocrinology and the Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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- Engstrom, Britt Eden (författare)
- Uppsala Univ Hosp, Sweden,Uppsala University Hospital, Uppsala, Sweden
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- Johannsson, Gudmundur, 1960 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Sahlgrens Univ Hosp, Sweden; Univ Gothenburg, Sweden; Sahlgrens Univ Hosp, Sweden,Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden; Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg & Sahlgrenska University Hospital, Gothenburg, Sweden
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- Ragnarsson, Oskar (författare)
- Sahlgrens Univ Hosp, Sweden,Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden
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- Olsson, Daniel S, 1983 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Sahlgrens Univ Hosp, Sweden; Univ Gothenburg, Sweden; AstraZeneca, Sweden,Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden; Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg & Sahlgrenska University Hospital, Gothenburg, Sweden; Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden
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- Sigurjonsdottir, Helga agusta (författare)
- Natl Univ Hosp Iceland, Iceland; Univ Iceland, Iceland,The National University Hospital of Iceland, Gothenburg, Iceland; School of Medicine, University of Iceland, Reykjavik, Iceland
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- Fougner, Stine Lyngvi (författare)
- Trondheim Reg & Univ Hosp, Norway; Norwegian Univ Sci & Technol NTNU, Norway,Department of Endocrinology, St. Olavs hospital, Trondheim University Hospital, Trondheim, Norway; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
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- Matikainen, Niina (författare)
- Helsinki Univ Hosp, Finland,Helsinki University Hospital, Helsinki, Finland
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- Vehkavaara, Satu (författare)
- Helsinki Univ Hosp, Finland,Helsinki University Hospital, Helsinki, Finland
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- Metso, Saara (författare)
- Tampere Univ Hosp, Finland,Tampere University Hospital, Tampere, Finland
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- Jaatinen, Pia (författare)
- Tampere Univ Hosp, Finland,Tampere University Hospital, Tampere, Finland
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- Haemalainen, Paeivi (författare)
- Tampere Univ Hosp, Finland,Tampere University Hospital, Tampere, Finland
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- Rintamaki, Reeta (författare)
- Kuopio Univ Hosp, Finland,Kuopio University Hospital, Kuopio, Finland
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- Yliaska, Iina (författare)
- Oulu Univ Hosp, Finland,Oulu University Hospital, Oulu, Finland
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- Immonen, Heidi (författare)
- Turku Univ Hosp, Finland,Turku University Hospital, Turku, Finland
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- Makimattila, Sari (författare)
- Helsinki Univ Hosp, Finland,Helsinki University Hospital, Helsinki, Finland
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- Cederberg-Tamminen, Henna (författare)
- Helsinki Univ Hosp, Finland,Helsinki University Hospital, Helsinki, Finland
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- Viukari, Marianna (författare)
- Helsinki Univ Hosp, Finland,Helsinki University Hospital, Helsinki, Finland
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- Nevalainen, Pasi (författare)
- Tampere Univ Hosp, Finland,Tampere University Hospital, Tampere, Finland
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- Nuutila, Pirjo (författare)
- Turku Univ Hosp, Finland,Turku University Hospital, Turku, Finland
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- Schalin-Jantti, Camilla (författare)
- Helsinki Univ Hosp, Finland,Helsinki University Hospital, Helsinki, Finland
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- Burman, Pia (författare)
- Lund Univ, Sweden,Skåne University Hospital, Lund University, Malmö, Sweden
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- Jorgensen, Jens Otto Lunde (författare)
- Aarhus Univ Hosp, Denmark,Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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(creator_code:org_t)
- WILEY, 2024
- 2024
- Engelska.
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Ingår i: CLINICAL ENDOCRINOLOGY. - : WILEY. - 0300-0664 .- 1365-2265.
- Relaterad länk:
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https://doi.org/10.1...
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visa fler...
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https://umu.diva-por... (primary) (Raw object)
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- ObjectiveAcromegaly is associated with increased morbidity and mortality if left untreated. The therapeutic options include surgery, medical treatment, and radiotherapy. Several guidelines and recommendations on treatment algorithms and follow-up exist. However, not all recommendations are strictly evidence-based. To evaluate consensus on the treatment and follow-up of patients with acromegaly in the Nordic countries.MethodsA Delphi process was used to map the landscape of acromegaly management in Denmark, Sweden, Norway, Finland, and Iceland. An expert panel developed 37 statements on the treatment and follow-up of patients with acromegaly. Dedicated endocrinologists (n = 47) from the Nordic countries were invited to rate their extent of agreement with the statements, using a Likert-type scale (1-7). Consensus was defined as >= 80% of panelists rating their agreement as >= 5 or <= 3 on the Likert-type scale.ResultsConsensus was reached in 41% (15/37) of the statements. Panelists agreed that pituitary surgery remains first line treatment. There was general agreement to recommend first-generation somatostatin analog (SSA) treatment after failed surgery and to consider repeat surgery. In addition, there was agreement to recommend combination therapy with first-generation SSA and pegvisomant as second- or third-line treatment. In more than 50% of the statements, consensus was not achieved. Considerable disagreement existed regarding pegvisomant monotherapy, and treatment with pasireotide and dopamine agonists.ConclusionThis consensus exploration study on the management of patients with acromegaly in the Nordic countries revealed a relatively large degree of disagreement among experts, which mirrors the complexity of the disease and the shortage of evidence-based data.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- acromegaly
- Delphi
- dopamine agonist
- growth hormone
- growth hormone receptor antagonist
- insulin-like growth factor i
- somatostatin
- acromegaly; Delphi; dopamine agonist; growth hormone; growth hormone receptor antagonist; insulin-like growth factor i; somatostatin
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Arlien-Soborg, M ...
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Dal, Jakob
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Heck, Ansgar
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Stochholm, Kirst ...
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Husted, Eigil
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Feltoft, Claus L ...
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visa fler...
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Rasmussen, ase K ...
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Feldt-Rasmussen, ...
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Andreassen, Mikk ...
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Klose, Marianne ...
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Nielsen, Torben ...
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Andersen, Marian ...
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Christensen, Lou ...
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Krogh, Jesper
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Jarlov, Anne
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Bollerslev, Jens
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Nermoen, Ingrid
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Oksnes, Marianne
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Dahlqvist, Per
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Olsson, Tommy
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Berinder, Katari ...
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Hoybye, Charlott ...
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Petersson, Maria
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Akerman, Anna-ka ...
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Wahlberg, Jeanet ...
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Ekman, Bertil
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Engstrom, Britt ...
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Johannsson, Gudm ...
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Ragnarsson, Oska ...
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Olsson, Daniel S ...
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Sigurjonsdottir, ...
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Fougner, Stine L ...
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Matikainen, Niin ...
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Vehkavaara, Satu
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Metso, Saara
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Jaatinen, Pia
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Haemalainen, Pae ...
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Rintamaki, Reeta
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Yliaska, Iina
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Immonen, Heidi
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Makimattila, Sar ...
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Cederberg-Tammin ...
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Viukari, Mariann ...
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Nevalainen, Pasi
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Nuutila, Pirjo
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Schalin-Jantti, ...
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Burman, Pia
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Jorgensen, Jens ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Endokrinologi oc ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Anestesi och int ...
- Artiklar i publikationen
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CLINICAL ENDOCRI ...
- Av lärosätet
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Göteborgs universitet
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Linköpings universitet
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Umeå universitet