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Sökning: WFRF:(Arnarsson Arsaell) > The 7-year cumulati...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003604naa a2200445 4500
001oai:DiVA.org:uu-169659
003SwePub
008120305s2013 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1696592 URI
024a https://doi.org/10.1111/j.1755-3768.2011.02360.x2 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Zoega, Gunnar Mar,d 1973-u Uppsala universitet,Oftalmiatrik4 aut0 (Swepub:uu)aaaaa798
2451 0a The 7-year cumulative incidence of cornea guttata and morphological changes in the corneal endothelium in the Reykjavik Eye Study
264 c 2012-02-17
264 1b Wiley,c 2013
338 a print2 rdacarrier
520 a Purpose: To examine the corneal endothelium and establish the 7-year cumulativeincidence of cornea guttata (CG).Methods: Population-based prospective cohort study with 573 participants(third wave of the Reykjavik Eye Study (RES) in 2008). Four hundred and thirty-seven subjects had either right or left eyes available for analysis after excluding confounding eye conditions. The baseline for eyes at risk for developing CG is the second wave of the RES in 2001. Participants underwent specular microscopy and a standardized eye examination.Results: The cumulative 7-year incidence of CG in either eye was estimated as a 95% confidence interval for the expected value for both genders combined (15–23%), for males (8–18%) and for females (19–29%). In right eye only, the 7-year cumulative incidence for both genders combined was estimated to be 6–11%. For genders combined and for males only, the data indicated no correlation between 7-year cumulated incidence and age at baseline. In women, however, the change of 7-year incidence for CG in at least one eye appeared to be correlated to age at baseline. Reduction of endothelial cell density for corneas with CG at baseline was found [CI (0.95))132 ± 94].Conclusion: The cumulative 7-year incidence of primary central CG for a middle-aged and older Caucasian population without history of potentially confounding eye disease has been established. Women tend to have higher incidence if onset occurs at middle age. If CG is present, the cell density and the cell size variation decrease within a 7-year period.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Oftalmologi0 (SwePub)302172 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Ophthalmology0 (SwePub)302172 hsv//eng
653 a cornea guttata
653 a endothelium
653 a incidence
653 a morphology
653 a population based
653 a specular microscopy
653 a Epidemiology
653 a Epidemiologi
700a Arnarsson, Arsaellu Neuroscience Research, University of Akureyri, Akureyri, Iceland4 aut
700a Sasaki, Hiroshiu Dept. of Ophthalmology, Kanazawa Medical University, Uchinada, Japan4 aut
700a Söderberg, Peru Uppsala universitet,Oftalmiatrik4 aut0 (Swepub:uu)perso438
700a Jonasson, Fridbertu Dept. of Ophthalmology, University of Iceland, Reykjavik, Iceland4 aut
710a Uppsala universitetb Oftalmiatrik4 org
773t Acta Ophthalmologicad : Wileyg 91:3, s. 212-218q 91:3<212-218x 1755-375Xx 1755-3768
856u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1755-3768.2011.02360.x
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-169659
8564 8u https://doi.org/10.1111/j.1755-3768.2011.02360.x

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