WFRF:(Cassimjee Karim Engelmark)
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Transaminations with isopropyl amine : equilibrium displacement with yeast alcohol dehydrogenase coupled to in situ cofactor regeneration
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- Engelmark Cassimjee, Karim (author)
- KTH,Biokemi
- Branneby, Cecilia (author)
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- Abedi, Vahak (author)
- AstraZeneca
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- Royal Society of Chemistry (RSC), 2010
- 2010
- English.
- In: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1359-7345 .- 1364-548X. ; 46:30, s. 5569-5571
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Enantiopure chiral amines synthesis using omega-transaminases is hindered by an unfavourable equilibrium, but when using isopropylamine as the amine donor the equilibrium can be completely displaced by using a specific dehydrogenase in situ for removal of formed acetone.
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Keyword
- OPTICALLY-ACTIVE AMINES
- ASYMMETRIC-SYNTHESIS
- OMEGA-TRANSAMINASES
- CHIRAL AMINES
- Biochemistry
- Biokemi
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Royal Institute of Technology
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