Sökning: WFRF:(Fellman Vineta) > Assessment of Brain...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 05825naa a2200721 4500 | |
001 | oai:lup.lub.lu.se:9b88ec94-2d70-4cb9-be62-3af044767dd1 | |
003 | SwePub | |
008 | 231019s2019 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/9b88ec94-2d70-4cb9-be62-3af044767dd12 URI |
024 | 7 | a https://doi.org/10.1016/j.jpeds.2018.12.0622 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Cizmeci, Mehmet Nu University Medical Center Utrecht4 aut |
245 | 1 0 | a Assessment of Brain Injury and Brain Volumes after Posthemorrhagic Ventricular Dilatation : A Nested Substudy of the Randomized Controlled ELVIS Trial |
264 | 1 | b Elsevier BV,c 2019 |
520 | a OBJECTIVE: To compare the effect of early and late intervention for posthemorrhagic ventricular dilatation on additional brain injury and ventricular volume using term-equivalent age-MRI.STUDY DESIGN: In the Early vs Late Ventricular Intervention Study (ELVIS) trial, 126 preterm infants ≤34 weeks of gestation with posthemorrhagic ventricular dilatation were randomized to low-threshold (ventricular index >p97 and anterior horn width >6 mm) or high-threshold (ventricular index >p97 + 4 mm and anterior horn width >10 mm) groups. In 88 of those (80%) with a term-equivalent age-MRI, the Kidokoro Global Brain Abnormality Score and the frontal and occipital horn ratio were measured. Automatic segmentation was used for volumetric analysis.RESULTS: The total Kidokoro score of the infants in the low-threshold group (n = 44) was lower than in the high-threshold group (n = 44; median, 8 [IQR, 5-12] vs median 12 [IQR, 9-17], respectively; P < .001). More infants in the low-threshold group had a normal or mildly increased score vs more infants in the high-threshold group with a moderately or severely increased score (46% vs 11% and 89% vs 54%, respectively; P = .002). The frontal and occipital horn ratio was lower in the low-threshold group (median, 0.42 [IQR, 0.34-0.63]) than the high-threshold group (median 0.48 [IQR, 0.37-0.68], respectively; P = .001). Ventricular cerebrospinal fluid volumes could be calculated in 47 infants and were smaller in the low-threshold group (P = .03).CONCLUSIONS: More brain injury and larger ventricular volumes were demonstrated in the high vs the low-threshold group. These results support the positive effects of early intervention for posthemorrhagic ventricular dilatation.TRIAL REGISTRATION: ISRCTN43171322. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
653 | a Brain/diagnostic imaging | |
653 | a Brain Injuries/diagnostic imaging | |
653 | a Cerebral Hemorrhage/diagnostic imaging | |
653 | a Cerebral Ventricles/diagnostic imaging | |
653 | a Cerebrospinal Fluid | |
653 | a Cerebrospinal Fluid Shunts | |
653 | a Dilatation | |
653 | a Female | |
653 | a Humans | |
653 | a Hydrocephalus/diagnostic imaging | |
653 | a Infant, Newborn | |
653 | a Infant, Premature | |
653 | a Infant, Premature, Diseases/diagnostic imaging | |
653 | a Intracranial Hemorrhages/diagnostic imaging | |
653 | a Magnetic Resonance Imaging | |
653 | a Male | |
653 | a White Matter/diagnostic imaging | |
700 | 1 | a Khalili, Nadiehu University Medical Center Utrecht4 aut |
700 | 1 | a Claessens, Nathalie H Pu University Medical Center Utrecht4 aut |
700 | 1 | a Groenendaal, Florisu University Medical Center Utrecht4 aut |
700 | 1 | a Liem, Kian Du Radboud University Medical Center4 aut |
700 | 1 | a Heep, Axelu University of Bristol4 aut |
700 | 1 | a Benavente-Fernández, Isabelu Puerta del Mar University Hospital4 aut |
700 | 1 | a van Straaten, Henrica L Mu Isala Women and Children's Hospital4 aut |
700 | 1 | a van Wezel-Meijler, Gerdau Leiden University Medical Centre4 aut |
700 | 1 | a Steggerda, Sylke Ju Leiden University Medical Centre4 aut |
700 | 1 | a Dudink, Jeroenu University Medical Center Utrecht4 aut |
700 | 1 | a Išgum, Ivanau University Medical Center Utrecht4 aut |
700 | 1 | a Whitelaw, Andrewu University of Bristol4 aut |
700 | 1 | a Benders, Manon J N Lu University Medical Center Utrecht4 aut |
700 | 1 | a de Vries, Linda Su University Medical Center Utrecht4 aut |
700 | 1 | a Ley, Davidu Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neonatalogi,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Neonatology,Lund University Research Groups4 cre0 (Swepub:lu)pedi-dle |
700 | 1 | a Fellman, Vinetau Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 cre0 (Swepub:lu)pedi-vfe |
710 | 2 | a University Medical Center Utrechtb Radboud University Medical Center4 org |
710 | 2 | a ELVIS study group |
773 | 0 | t Journal of Pediatricsd : Elsevier BVg 208, s. 2-197q 208<2-197x 1097-6833x 0022-3476 |
856 | 4 | u http://dx.doi.org/10.1016/j.jpeds.2018.12.062y FULLTEXT |
856 | 4 | u https://research-information.bris.ac.uk/ws/files/205028352/Manuscript_R10_1_.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/9b88ec94-2d70-4cb9-be62-3af044767dd1 |
856 | 4 8 | u https://doi.org/10.1016/j.jpeds.2018.12.062 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
Kopiera och spara länken för att återkomma till aktuell vy