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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005138naa a2200601 4500
001oai:DiVA.org:uu-264812
003SwePub
008151019s2015 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:132036118
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2648122 URI
024a https://doi.org/10.1093/aje/kwv0812 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1320361182 URI
040 a (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Hollander, Peteru Uppsala universitet,Klinisk och experimentell patologi,Rose-Marie Amini4 aut0 (Swepub:uu)petho189
2451 0a Autoimmune and Atopic Disorders and Risk of Classical Hodgkin Lymphoma
264 c 2015-09-06
264 1b Oxford University Press (OUP),c 2015
338 a print2 rdacarrier
520 a Results from previous investigations have shown associations between the risk of Hodgkin lymphoma (HL) and a history of autoimmune and atopic diseases, but it remains unknown whether these associations apply to all types of HL or only to specific subtypes. We investigated immune diseases and the risk of classical HL in a population-based case-control study that included 585 patients and 3,187 controls recruited from October 1999 through August 2002. We collected information on immune diseases through telephone interviews and performed serological analyses of specific immunoglobulin E reactivity. Tumor Epstein-Barr virus (EBV) status was determined for 498 patients. Odds ratios with 95% confidence intervals were calculated using logistic regression analysis. Rheumatoid arthritis was associated with a higher risk of HL (odds ratio (OR) = 2.63; 95% confidence interval (CI): 1.47, 4.70), especially EBV-positive HL (OR = 3.18; 95% CI: 1.23, 8.17), and with mixed-cellularity HL (OR = 4.25; 95% CI: 1.66, 10.90). HL risk was higher when we used proxies of severe rheumatoid arthritis, such as ever having received daily rheumatoid arthritis medication (OR = 3.98; 95% CI: 2.08, 7.62), rheumatoid arthritis duration of 6-20 years (OR = 3.80; 95% CI: 1.72, 8.41), or ever having been hospitalized for rheumatoid arthritis (OR = 7.36; 95% CI: 2.95, 18.38). Atopic diseases were not associated with the risk of HL. EBV replication induced by chronic inflammation in patients with autoimmune diseases might explain the higher risk of EBV-positive HL.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Arbetsmedicin och miljömedicin0 (SwePub)303032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Occupational Health and Environmental Health0 (SwePub)303032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Klinisk laboratoriemedicin0 (SwePub)302232 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Clinical Laboratory Medicine0 (SwePub)302232 hsv//eng
653 a atopic hypersensitivity
653 a Epstein-Barr virus
653 a Hodgkin lymphoma
653 a primary Sjogren's syndrome
653 a rheumatoid arthritis
653 a systemic lupus erythematosus
653 a Pathology
653 a Patologi
700a Rostgaard, Klausu Statens Serum Inst, Dept Epidemiol Res, DK-2300 Copenhagen S, Denmark.4 aut
700a Smedby, Karin E.u Karolinska Institutet4 aut
700a Chang, Ellen T.u Stanford Univ, Sch Med, Dept Hlth Res & Policy, Div Epidemiol, Stanford, CA 94305 USA.;Exponent Inc, Hlth Sci, Menlo Pk, CA USA.4 aut
700a Amini, Rose-Marieu Uppsala universitet,Klinisk och experimentell patologi,Rose-Marie Amini4 aut0 (Swepub:uu)roseamin
700a Brown, Peter de Nullyu Rigshosp, Dept Haematol, DK-2100 Copenhagen, Denmark.4 aut
700a Glimelius, Bengtu Uppsala universitet,Experimentell och klinisk onkologi4 aut0 (Swepub:uu)bengglim
700a Adami, Hans-Olovu Karolinska Institutet4 aut
700a Melbye, Madsu Stanford Univ, Sch Med, Dept Med, Stanford, CA 94305 USA.4 aut
700a Glimelius, Ingridu Karolinska Institutet,Uppsala universitet,Experimentell och klinisk onkologi4 aut0 (Swepub:uu)inggl846
700a Hjalgrim, Henriku Statens Serum Inst, Dept Epidemiol Res, DK-2300 Copenhagen S, Denmark.4 aut
710a Uppsala universitetb Klinisk och experimentell patologi4 org
773t American Journal of Epidemiologyd : Oxford University Press (OUP)g 182:7, s. 624-632q 182:7<624-632x 0002-9262x 1476-6256
856u https://academic.oup.com/aje/article-pdf/182/7/624/250746/kwv081.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-264812
8564 8u https://doi.org/10.1093/aje/kwv081
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:132036118

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