Sökning: WFRF:(Gressens Pierre) > Inflammation-induce...
Fältnamn | Indikatorer | Metadata |
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000 | 03137naa a2200601 4500 | |
001 | oai:gup.ub.gu.se/224239 | |
003 | SwePub | |
008 | 240528s2015 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/2242392 URI |
024 | 7 | a https://doi.org/10.1111/dmcn.127232 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Fleiss, Bobbi4 aut |
245 | 1 0 | a Inflammation-induced sensitization of the brain in term infants. |
264 | c 2015-03-19 | |
264 | 1 | b Wiley,c 2015 |
520 | a Perinatal insults are a leading cause of infant mortality and amongst survivors are frequently associated with neurocognitive impairment, cerebral palsy (CP), and seizure disorders. The events leading to perinatal brain injury are multifactorial. This review describes how one subinjurious factor affecting the brain sensitizes it to a second injurious factor, causing an exacerbated injurious cascade. We will review the clinical and experimental evidence, including observations of high rates of maternal and fetal infections in term-born infants with neonatal encephalopathy and cerebral palsy. In addition, we will discuss preclinical evidence for the sensitizing effects of inflammation on injuries, such as hypoxia-ischaemia, our current understanding of the mechanisms underpinning the sensitization process, and the possibility for neuroprotection. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
653 | a Animals | |
653 | a Brain | |
653 | a abnormalities | |
653 | a Brain Injuries | |
653 | a etiology | |
653 | a Female | |
653 | a Gene Expression Regulation | |
653 | a Developmental | |
653 | a Humans | |
653 | a Infant | |
653 | a Infant | |
653 | a Newborn | |
653 | a Inflammation | |
653 | a complications | |
653 | a Maternal-Fetal Exchange | |
653 | a Pregnancy | |
700 | 1 | a Tann, Cally J4 aut |
700 | 1 | a Degos, Vincent4 aut |
700 | 1 | a Sigaut, Stéphanie4 aut |
700 | 1 | a Van Steenwinckel, Juliette4 aut |
700 | 1 | a Schang, Anne-Laure4 aut |
700 | 1 | a Kichev, Anton4 aut |
700 | 1 | a Robertson, Nicola J4 aut |
700 | 1 | a Mallard, Carina,d 1963u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology4 aut0 (Swepub:gu)xmallc |
700 | 1 | a Hagberg, Henrik,d 19554 aut |
700 | 1 | a Gressens, Pierre4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi4 org |
773 | 0 | t Developmental medicine and child neurologyd : Wileyg 57 Suppl 3, s. 17-28q 57 Suppl 3<17-28x 1469-8749x 0012-1622 |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dmcn.12723 |
856 | 4 8 | u https://gup.ub.gu.se/publication/224239 |
856 | 4 8 | u https://doi.org/10.1111/dmcn.12723 |
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