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Sökning: WFRF:(Hakansson Niclas) > Uppsala universitet > Diet Quality and Ri...

Diet Quality and Risk of Older-Onset Crohn's Disease and Ulcerative Colitis

Khalili, Hamed (författare)
Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden,Harvard Med Sch, Massachusetts Gen Hosp, Gastroenterol Unit, Boston, MA USA.;Harvard Med Sch, Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA USA.;Karolinska Inst, Inst Environm Med, Stockholm, Sweden.
Hakansson, Niclas (författare)
Karolinska Institutet,Karolinska Inst, Inst Environm Med, Stockholm, Sweden.
Casey, Kevin (författare)
Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA,Harvard Med Sch, Massachusetts Gen Hosp, Gastroenterol Unit, Boston, MA USA.;Harvard Med Sch, Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA USA.
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Lopes, Emily (författare)
Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA,Harvard Med Sch, Massachusetts Gen Hosp, Gastroenterol Unit, Boston, MA USA.;Harvard Med Sch, Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA USA.
Ludvigsson, Jonas F., 1969- (författare)
Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Örebro University Hospital, Örebro, Sweden,Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.;Örebro Univ, Örebro Univ Hosp, Dept Pediat, Örebro, Sweden.
Chan, Andrew T. (författare)
Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA,Harvard Med Sch, Massachusetts Gen Hosp, Gastroenterol Unit, Boston, MA USA.;Harvard Med Sch, Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA USA.
Chan, Simon S. M. (författare)
Department of Medicine, Norwich Medical School, University of East Anglia, Norwich, United Kingdom; Department of Gastroenterology, Norfolk and Norwich University Hospital NHS Trust, Norwich, United Kingdom,Univ East Anglia, Norwich Med Sch, Dept Med, Norwich, Norfolk, England.;Norfolk & Norwich Univ Hosp NHS Trust, Dept Gastroenterol, Norwich, Norfolk, England.
Olen, Ola (författare)
Karolinska Institutet,Karolinska Inst, Clin Epidemiol Div, Dept Med Solna, Stockholm, Sweden.;Sachs Childrens Hosp, Pediat Gastroenterol & Nutr Unit, Stockholm, Sweden.
Wolk, Alicja (författare)
Uppsala universitet,Karolinska Institutet,Medicinsk epidemiologi,Karolinska Inst, Inst Environm Med, Stockholm, Sweden
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Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden Harvard Med Sch, Massachusetts Gen Hosp, Gastroenterol Unit, Boston, MA USA;Harvard Med Sch, Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA USA.;Karolinska Inst, Inst Environm Med, Stockholm, Sweden. (creator_code:org_t)
2022-12-15
2023
Engelska.
Ingår i: Journal of Crohn's & Colitis. - : Oxford University Press. - 1873-9946 .- 1876-4479. ; 17:5, s. 746-753
Relaterad länk:
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • BACKGROUND: To assess the relationship between diet quality and risk of older-onset Crohn's disease (CD) and ulcerative colitis (UC).METHODS: We conducted a prospective cohort study of 83,147 participants from the Swedish Mammography Cohort and the Cohort of Swedish Men. We used food frequency questionnaire to calculate adherence scores to multiple derived health diet patterns: Alternate Healthy Eating Index (AHEI), Healthy Eating Index-2015 (HEI-2015), Healthful Plant-Based Diet Index (HPDI), and modified Mediterranean Diet Score (mMED) at baseline in 1997 in both cohorts. Diagnoses of CD and UC were retrieved from the Swedish Patient Register. We used Cox proportional hazards modeling to estimate the adjusted hazard ratios (HRs) and 95% CIs.FINDINGS: Through December of 2017, we confirmed 164 incident cases of CD and 395 incident cases of UC. Comparing the highest to the lowest quartiles, the adjusted HRs of CD were 0.73 (95% CI, 0.48, 1.12, Ptrend = 0.123) for AHEI; 0.90 (0.57, 1.41, Ptrend = 0.736) for HEI 2015; 0.52 (95% CI 0.32, 0.85, Ptrend = 0.011) for HPDI; and 0.58 (95% CI 0.32, 1.06, Ptrend = 0.044) for mMED. In contrast, we did not observe an association between any diet quality score and risk of UC.INTERPRETATION: We found that several healthy eating patterns were associated with a lower risk of older-onset CD. Our findings provide a rationale for adapting different healthy dietary patterns based on individuals' food preferences and traditions for designing future prevention strategies for IBD.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Näringslära (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nutrition and Dietetics (hsv//eng)

Nyckelord

Crohn's disease
diet quality
epidemiology
nutrition
ulcerative colitis

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