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Association of obes...
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Toimela, J.S.Research Unit of Clinical Medicine, University of Oulu, P.O. Box 5000, Oulu, Finland
(författare)
Association of obesity to reaction time and visual memory in schizophrenia
- Artikel/kapitelEngelska2024
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Elsevier,2024
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electronicrdacarrier
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LIBRIS-ID:oai:DiVA.org:umu-224391
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-224391URI
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https://doi.org/10.1016/j.scog.2024.100316DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Background: Both overweight and cognitive deficits are common among people with schizophrenia (SZ) and schizoaffective disorder. The results in earlier studies have been inconsistent on whether overweight is associated with cognitive deficits in psychotic disorders.Aims: Our aim in this study was to detect possible associations between obesity and cognitive deficits among study participants with SZ and schizoaffective disorder.Methods: The study sample included 5382 participants with a clinical diagnosis of SZ or schizoaffective disorder selected from the Finnish SUPER study. Obesity was measured both with body-mass index and waist circumference. The cognitive performance was evaluated with two tests from the Cambridge automated neuropsychological test battery: Reaction time was evaluated with the 5-choice serial reaction time task. Visual memory was evaluated with the paired associative learning test. The final analysis included a total sample of 4498 participants applicable for the analysis of the reaction time and 3967 participants for the analysis of the visual memory.Results: Obesity measured with body-mass index was associated with better performance in reaction time task among both female and male participants. Among male participants, overweight was associated with better performance in the visual memory test. The waist circumference was not associated with cognitive measures.Conclusions: The results suggest that obesity in people with SZ or schizoaffective disorder might not be associated with cognitive deficits but instead with better cognitive performance. The results were opposite from earlier literature on the general population. More research is required to better understand whether the results might be partly caused by the differences in the etiology of obesity between the general population and people with SZ.
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Halt, A.H.Research Unit of Clinical Medicine, University of Oulu, P.O. Box 5000, Oulu, Finland; Department of Psychiatry, Oulu University Hospital, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
(författare)
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Kerkelä, M.Research Unit of Clinical Medicine, University of Oulu, P.O. Box 5000, Oulu, Finland
(författare)
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Kampman, OlliUmeå universitet,Psykiatri,University of Turku, Faculty of Medicine, Department of Clinical Medicine (Psychiatry), Turku, Finland; The Wellbeing Services Country of Ostrobothnia, Department of Psychiatry, Vaasa, Finland; The Pirkanmaa Wellbeing Services Country, Department of Psychiatry, Tampere, Finland(Swepub:umu)kaol0168
(författare)
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Suvisaari, J.Mental Health Unit, Finnish Institute for Health and Welfare (THL), Helsinki, Finland
(författare)
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Kieseppä, T.Mental Health Unit, Finnish Institute for Health and Welfare (THL), Helsinki, Finland; University of Helsinki, Helsinki University Hospital, Psychiatry, Helsinki, Finland
(författare)
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Lähteenvuo, M.Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio, Finland
(författare)
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Tiihonen, J.Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio, Finland; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Center for Psychiatry Research, Stockholm City Council, Stockholm, Sweden
(författare)
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Ahola-Olli, A.Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland; Department of Internal Medicine, Satasairaala Hospital, Pori, Finland
(författare)
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Veijola, J.Research Unit of Clinical Medicine, University of Oulu, P.O. Box 5000, Oulu, Finland; Department of Psychiatry, Oulu University Hospital, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
(författare)
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Holm, M.Mental Health Unit, Finnish Institute for Health and Welfare (THL), Helsinki, Finland
(författare)
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Research Unit of Clinical Medicine, University of Oulu, P.O. Box 5000, Oulu, FinlandResearch Unit of Clinical Medicine, University of Oulu, P.O. Box 5000, Oulu, Finland; Department of Psychiatry, Oulu University Hospital, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
(creator_code:org_t)
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Ingår i:Schizophrenia Research: Elsevier372215-0013
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Toimela, J.S.
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Halt, A.H.
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Kerkelä, M.
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Kampman, Olli
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Suvisaari, J.
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Kieseppä, T.
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visa fler...
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Lähteenvuo, M.
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Tiihonen, J.
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Ahola-Olli, A.
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Veijola, J.
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Holm, M.
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