WFRF:(LINDBLAD B)
Sökning: WFRF:(LINDBLAD B) > (1990-1999) > Glutathione transfe...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04497naa a2200529 4500 | |
| 001 | oai:lup.lub.lu.se:f3ba5f9f-c6a1-49c9-81cc-f133867e7c55 | |
| 003 | SwePub | |
| 008 | 170811s1993 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/f3ba5f9f-c6a1-49c9-81cc-f133867e7c552 URI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Pessah-Rasmussen, Hu Lund University,Lunds universitet,Rehabiliteringsmedicin,Forskargrupper vid Lunds universitet,Rehabilitation medicine,Lund University Research Groups4 aut0 (Swepub:lu)neur-hpe |
| 245 | 1 0 | a Glutathione transferase activity in human vessels and in cultured arterial smooth muscle cells |
| 264 | 1 | c 1993 |
| 520 | a Glutathione transferases play an important role in the detoxification of many different endogeneous and exogenous compounds such as metabolites of polycyclic aromatic hydrocarbons (PAH) of cigarette tar. There is evidence that PAH may be atherogenic. The glutathione transferase activity towards trans-stilbene oxide (GST-tSBO) can be separated in blood in GST-positive and GST-negative phenotypes. We have previously suggested that the GST-negative phenotype may be associated with a higher morbidity in intermittent claudication among middle aged smokers. In the present study, GST-tSBO could easily be measured in human, rabbit and bovine arterial smooth muscle cells (SMC) in culture. The level of GST-tSBO was higher in rabbit than in bovine SMC. It was stable in bovine SMC during 5 cell passages and it could be induced twofold by long-time incubation with dimethylsulfoxide-soluble particulate matter from cigarette smoke or 3,4-benzo(a)pyrene. There was a positive correlation between the level of GST-tSBO in blood and in "healthy" arterial and venous tissue from individuals operated with coronary bypass. The enzyme levels in arterial tissue were lower than in venous tissue. GST-tSBO in atherosclerotic segments of human arteries was lower than in "healthy" segments from the same artery. These findings suggest that the arterial wall may have a low defense against toxic compounds that may decrease further as atherosclerosis proceeds. It is concluded that SMC are suitable for the study of the effects of PAH in relation to GST-tSBO and that the enzyme activity in blood will reflect the individual GST-tSBO phenotype also in vascular tissues. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
| 653 | a Adult | |
| 653 | a Animals | |
| 653 | a Arteriosclerosis | |
| 653 | a Cattle | |
| 653 | a Cells, Cultured | |
| 653 | a Female | |
| 653 | a Glutathione Transferase | |
| 653 | a Humans | |
| 653 | a In Vitro Techniques | |
| 653 | a Male | |
| 653 | a Middle Aged | |
| 653 | a Muscle, Smooth, Vascular | |
| 653 | a Phenotype | |
| 653 | a Polycyclic Compounds | |
| 653 | a Rabbits | |
| 653 | a Smoking | |
| 653 | a Stilbenes | |
| 653 | a Journal Article | |
| 653 | a Research Support, Non-U.S. Gov't | |
| 700 | 1 | a Seidegård, Ju Lund University,Lunds universitet,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)extLU-263 |
| 700 | 1 | a Stavenow, L.4 aut |
| 700 | 1 | a Solem, J Ou Lund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)thor-jso |
| 700 | 1 | a Lindblad, Bu Lund University,Lunds universitet,Vaskulära sjukdomar - kliniska studier,Forskargrupper vid Lunds universitet,Vascular Diseases - Clinical Research,Lund University Research Groups4 aut0 (Swepub:lu)kir-bli |
| 700 | 1 | a Xu, C Bu Lund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-cxu |
| 710 | 2 | a Rehabiliteringsmedicinb Forskargrupper vid Lunds universitet4 org |
| 773 | 0 | t International Angiologyg 12:4, s. 54-348q 12:4<54-348x 0392-9590 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/f3ba5f9f-c6a1-49c9-81cc-f133867e7c55 |
Hitta via bibliotek
- International Angiology (Sök värdpublikationen i LIBRIS)
Till lärosätets databas
Hitta mer i SwePub
- Av författaren/redakt...
- Pessah-Rasmussen ...
- Seidegård, J
- Stavenow, L.
- Solem, J O
- Lindblad, B
- Xu, C B
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Kardiologi
- Artiklar i publikationen
- International An ...
- Av lärosätet
- Lunds universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
