SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Mantzoros Christos)
 

Sökning: WFRF:(Mantzoros Christos) > Serum adiponectin c...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003442naa a2200373 4500
001oai:DiVA.org:uu-273975
003SwePub
008160119s2004 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2739752 URI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Mantzoros, Christos4 aut
2451 0a Serum adiponectin concentrations in relation to maternal and perinatal characteristics in newborns.
264 1c 2004
338 a print2 rdacarrier
520 a OBJECTIVE: To assess serum adiponectin levels of neonates in relation to ponderal index and birth length with and without adjustment for potential confounding factors including maternal factors and perinatal characteristics.DESIGN: A cross-sectional study.METHODS: Three hundred and three newborns (Caucasian, singleton, full term, with a birth weight of > or =2500 g, and apparently healthy) were included in the study. Blood samples were collected from the newborns no later than the fifth day of life for measurements of adiponectin and major IGF system components (IGF-I, IGF-II, IGF binding protein-3 (IGFBP-3)). The data were analyzed using simple and multiple regression analyses.RESULTS: Adiponectin is substantially higher in neonates than in adults, with no evidence of the gender dimorphism observed among adults. We found an inverse association between neonatal adiponectin levels and newborn ponderal index and a positive association with newborn length by univariate analysis. We also found a statistically significant inverse association of adiponectin with jaundice/bilirubin, and a marginally significant positive association of this hormone with IGFBP-3 but no significant association with any maternal factors. In multivariate analysis, the inverse association between serum adiponectin and ponderal index does not remain significant after adjustment for potential confounding factors. In contrast, neonatal adiponectin levels correlate inversely significantly and independently with liver maturity and IGF-II and tend to remain positively associated with IGFBP-3 and increased birth length.CONCLUSIONS: An inverse association of adiponectin with ponderal index by univariate analysis is not independent from confounding factors. In contrast, the positive association between serum adiponectin and birth length may reflect either a direct effect of adiponectin or an adiponectin-mediated increase in the sensitivity of tissues to insulin and components of the IGF system, and needs to be explored further.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
7001 a Petridou, Eleni4 aut
7001 a Alexe, Delia-Marina4 aut
7001 a Skalkidou, Alkistis4 aut
7001 a Dessypris, Nick4 aut
7001 a Papathoma, Eugenia4 aut
7001 a Salvanos, Heraklis4 aut
7001 a Shetty, Greeshma4 aut
7001 a Gavrila, Alina4 aut
7001 a Kedikoglou, Simos4 aut
7001 a Chrousos, George4 aut
7001 a Trichopoulos, Dimitrios4 aut
7730 t European Journal of Endocrinologyg 151:6q 151:6x 0804-4643x 1479-683X
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-273975

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy