3-D Microwave Tomography Using the Soft Prior Regularization Technique: Evaluation in Anatomically Realistic MRI-Derived Numerical Breast Phantoms

(creator_code:org_t)

2019
2019
English.
In: IEEE Transactions on Biomedical Engineering. - 0018-9294 .- 1558-2531. ; 66:9, s. 2566-2575

Related links:: https://research.cha...; show more...; https://doi.org/10.1...; show less...

Abstract Subject headings

Objective: Fusion of magnetic resonance imaging (MRI) breast images with microwave tomography is accomplished through a soft prior technique, which incorporates spatial information (from MRI), i. e., accurate boundary location of different regions of interest, into the regularization process of the microwave image reconstruction algorithm. Methods: Numerical experiments were completed on a set of three-dimensional (3-D) breast geometries derived from MR breast data with different parenchymal densities, as well as a simulated tumor to evaluate the performance over a range of breast shapes, sizes, and property distributions. Results: When the soft prior regularization technique was applied, both permittivity and conductivity relative root mean square error values decreased by more than 87% across all breast densities, except in two cases where the error decrease was only 55% and 78%. In addition, the incorporation of structural priors increased contrast between tumor and fibroglandular tissue by 59% in permittivity and 192% in conductivity. Conclusion: This study confirmed that the soft prior algorithm is robust in 3-D and can function successfully across a range of complex geometries and tissue property distributions. Significance: This study demonstrates that our microwave tomography is capable of recovering accurate tissue property distributions when spatial information from MRI is incorporated through soft prior regularization.

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
NATURVETENSKAP -- Data- och informationsvetenskap -- Datorseende och robotik (hsv//swe)
NATURAL SCIENCES -- Computer and Information Sciences -- Computer Vision and Robotics (hsv//eng)
TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Image Processing (hsv//eng)

By the author/editor: Golnabi, Amir H.; Meaney, Paul M, ...; Geimer, Shireen ...; Paulsen, Keith D ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Radiology Nuclea ...

NATURAL SCIENCES: NATURAL SCIENCES; and Computer and Inf ...; and Computer Vision ...

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Medical Image Pr ...

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