Sökning: WFRF:(Wright Jason) > Genome-wide associa...
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000 | 10027naa a2202377 4500 | |
001 | oai:gup.ub.gu.se/149729 | |
003 | SwePub | |
008 | 240528s2011 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/1497292 URI |
024 | 7 | a https://doi.org/10.1038/ng.9412 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Artigas Soler, María4 aut |
245 | 1 0 | a Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. |
264 | c 2011-09-25 | |
264 | 1 | b Springer Science and Business Media LLC,c 2011 |
520 | a Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease. We tested genome-wide association with forced expiratory volume in 1 second and the ratio of forced expiratory volume in 1 second to forced vital capacity in 48,201 individuals of European ancestry with follow up of the top associations in up to an additional 46,411 individuals. We identified new regions showing association (combined P < 5 × 10(-8)) with pulmonary function in or near MFAP2, TGFB2, HDAC4, RARB, MECOM (also known as EVI1), SPATA9, ARMC2, NCR3, ZKSCAN3, CDC123, C10orf11, LRP1, CCDC38, MMP15, CFDP1 and KCNE2. Identification of these 16 new loci may provide insight into the molecular mechanisms regulating pulmonary function and into molecular targets for future therapy to alleviate reduced lung function. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
700 | 1 | a Loth, Daan W4 aut |
700 | 1 | a Wain, Louise V4 aut |
700 | 1 | a Gharib, Sina A4 aut |
700 | 1 | a Obeidat, Ma'en4 aut |
700 | 1 | a Tang, Wenbo4 aut |
700 | 1 | a Zhai, Guangju4 aut |
700 | 1 | a Zhao, Jing Hua4 aut |
700 | 1 | a Smith, Albert Vernon4 aut |
700 | 1 | a Huffman, Jennifer E4 aut |
700 | 1 | a Albrecht, Eva4 aut |
700 | 1 | a Jackson, Catherine M4 aut |
700 | 1 | a Evans, David M4 aut |
700 | 1 | a Cadby, Gemma4 aut |
700 | 1 | a Fornage, Myriam4 aut |
700 | 1 | a Manichaikul, Ani4 aut |
700 | 1 | a Lopez, Lorna M4 aut |
700 | 1 | a Johnson, Toby4 aut |
700 | 1 | a Aldrich, Melinda C4 aut |
700 | 1 | a Aspelund, Thor4 aut |
700 | 1 | a Barroso, Inês4 aut |
700 | 1 | a Campbell, Harry4 aut |
700 | 1 | a Cassano, Patricia A4 aut |
700 | 1 | a Couper, David J4 aut |
700 | 1 | a Eiriksdottir, Gudny4 aut |
700 | 1 | a Franceschini, Nora4 aut |
700 | 1 | a Garcia, Melissa4 aut |
700 | 1 | a Gieger, Christian4 aut |
700 | 1 | a Gislason, Gauti Kjartan4 aut |
700 | 1 | a Grkovic, Ivica4 aut |
700 | 1 | a Hammond, Christopher J4 aut |
700 | 1 | a Hancock, Dana B4 aut |
700 | 1 | a Harris, Tamara B4 aut |
700 | 1 | a Ramasamy, Adaikalavan4 aut |
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700 | 1 | a Heliövaara, Markku4 aut |
700 | 1 | a Homuth, Georg4 aut |
700 | 1 | a Hysi, Pirro G4 aut |
700 | 1 | a James, Alan L4 aut |
700 | 1 | a Jankovic, Stipan4 aut |
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700 | 1 | a Karrasch, Stefan4 aut |
700 | 1 | a Klopp, Norman4 aut |
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700 | 1 | a Liu, Yongmei4 aut |
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700 | 1 | a Brisman, Jonas,d 1954u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xbrijo |
700 | 1 | a Britton, John R4 aut |
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700 | 1 | a Curjuric, Ivan4 aut |
700 | 1 | a Dahgam, Santoshu Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xdaghs |
700 | 1 | a Deary, Ian J4 aut |
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700 | 1 | a Granell, Raquel4 aut |
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700 | 1 | a Harris, Sarah E4 aut |
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700 | 1 | a Hui, Jennie4 aut |
700 | 1 | a Hunter, Michael L4 aut |
700 | 1 | a Imboden, Medea4 aut |
700 | 1 | a Jameson, Karen A4 aut |
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700 | 1 | a Liu, Jason Z4 aut |
700 | 1 | a Marchini, Jonathan4 aut |
700 | 1 | a McKeever, Tricia4 aut |
700 | 1 | a Morris, Andrew D4 aut |
700 | 1 | a Olin, Anna-Carin,d 1960u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xolina |
700 | 1 | a Porteous, David J4 aut |
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700 | 1 | a Sayer, Avan Aihie4 aut |
700 | 1 | a Sayers, Ian4 aut |
700 | 1 | a Sly, Peter D4 aut |
700 | 1 | a Smith, George Davey4 aut |
700 | 1 | a Sood, Akshay4 aut |
700 | 1 | a Starr, John M4 aut |
700 | 1 | a Uitterlinden, André G4 aut |
700 | 1 | a Vonk, Judith M4 aut |
700 | 1 | a Wannamethee, S Goya4 aut |
700 | 1 | a Whincup, Peter H4 aut |
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700 | 1 | a Williams, O Dale4 aut |
700 | 1 | a Wong, Andrew4 aut |
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700 | 1 | a Marciante, Kristin D4 aut |
700 | 1 | a McArdle, Wendy L4 aut |
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700 | 1 | a Morrison, Alanna C4 aut |
700 | 1 | a North, Kari E4 aut |
700 | 1 | a Omenaas, Ernst4 aut |
700 | 1 | a Palmer, Lyle J4 aut |
700 | 1 | a Pietiläinen, Kirsi H4 aut |
700 | 1 | a Pin, Isabelle4 aut |
700 | 1 | a Pola Sbreve Ek, Ozren4 aut |
700 | 1 | a Pouta, Anneli4 aut |
700 | 1 | a Psaty, Bruce M4 aut |
700 | 1 | a Hartikainen, Anna-Liisa4 aut |
700 | 1 | a Rantanen, Taina4 aut |
700 | 1 | a Ripatti, Samuli4 aut |
700 | 1 | a Rotter, Jerome I4 aut |
700 | 1 | a Rudan, Igor4 aut |
700 | 1 | a Rudnicka, Alicja R4 aut |
700 | 1 | a Schulz, Holger4 aut |
700 | 1 | a Shin, So-Youn4 aut |
700 | 1 | a Spector, Tim D4 aut |
700 | 1 | a Surakka, Ida4 aut |
700 | 1 | a Vitart, Veronique4 aut |
700 | 1 | a Völzke, Henry4 aut |
700 | 1 | a Wareham, Nicholas J4 aut |
700 | 1 | a Warrington, Nicole M4 aut |
700 | 1 | a Wichmann, H-Erich4 aut |
700 | 1 | a Wild, Sarah H4 aut |
700 | 1 | a Wilk, Jemma B4 aut |
700 | 1 | a Wjst, Matthias4 aut |
700 | 1 | a Wright, Alan F4 aut |
700 | 1 | a Zgaga, Lina4 aut |
700 | 1 | a Zemunik, Tatijana4 aut |
700 | 1 | a Pennell, Craig E4 aut |
700 | 1 | a Nyberg, Fredrik,d 1961u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xnybef |
700 | 1 | a Kuh, Diana4 aut |
700 | 1 | a Holloway, John W4 aut |
700 | 1 | a Boezen, H Marike4 aut |
700 | 1 | a Lawlor, Debbie A4 aut |
700 | 1 | a Morris, Richard W4 aut |
700 | 1 | a Probst-Hensch, Nicole4 aut |
700 | 1 | a Kaprio, Jaakko4 aut |
700 | 1 | a Wilson, James F4 aut |
700 | 1 | a Hayward, Caroline4 aut |
700 | 1 | a Kähönen, Mika4 aut |
700 | 1 | a Heinrich, Joachim4 aut |
700 | 1 | a Musk, Arthur W4 aut |
700 | 1 | a Jarvis, Deborah L4 aut |
700 | 1 | a Gläser, Sven4 aut |
700 | 1 | a Järvelin, Marjo-Riitta4 aut |
700 | 1 | a Ch Stricker, Bruno H4 aut |
700 | 1 | a Elliott, Paul4 aut |
700 | 1 | a O'Connor, George T4 aut |
700 | 1 | a Strachan, David P4 aut |
700 | 1 | a London, Stephanie J4 aut |
700 | 1 | a Hall, Ian P4 aut |
700 | 1 | a Gudnason, Vilmundur4 aut |
700 | 1 | a International Lung Cancer Consortium,4 aut |
700 | 1 | a Tobin, Martin D4 aut |
700 | 1 | a GIANT Consortium,4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa4 org |
773 | 0 | t Nature geneticsd : Springer Science and Business Media LLCg 43:11, s. 1082-90q 43:11<1082-90x 1546-1718x 1061-4036 |
856 | 4 | u https://pure.mpg.de/pubman/item/item_1139639_16/component/file_1217552/Artigas_et_al_2011_Nature_Genetics.pdf |
856 | 4 8 | u https://gup.ub.gu.se/publication/149729 |
856 | 4 8 | u https://doi.org/10.1038/ng.941 |
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