Sökning: WFRF:(Zetterberg E.) > Advancing specifici...
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000 | 03965naa a2200649 4500 | |
001 | oai:gup.ub.gu.se/328852 | |
003 | SwePub | |
008 | 240528s2024 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/3288522 URI |
024 | 7 | a https://doi.org/10.1002/alz.134192 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Bowman, E. M. L.4 aut |
245 | 1 0 | a Advancing specificity in delirium: The delirium subtyping initiative |
264 | 1 | c 2024 |
520 | a BACKGROUNDDelirium, a common syndrome with heterogeneous etiologies and clinical presentations, is associated with poor long-term outcomes. Recording and analyzing all delirium equally could be hindering the field's understanding of pathophysiology and identification of targeted treatments. Current delirium subtyping methods reflect clinically evident features but likely do not account for underlying biology. METHODSThe Delirium Subtyping Initiative (DSI) held three sessions with an international panel of 25 experts. RESULTSMeeting participants suggest further characterization of delirium features to complement the existing Diagnostic and Statistical Manual of Mental Disorders Fifth Edition Text Revision diagnostic criteria. These should span the range of delirium-spectrum syndromes and be measured consistently across studies. Clinical features should be recorded in conjunction with biospecimen collection, where feasible, in a standardized way, to determine temporal associations of biology coincident with clinical fluctuations. DISCUSSIONThe DSI made recommendations spanning the breadth of delirium research including clinical features, study planning, data collection, and data analysis for characterization of candidate delirium subtypes. HighlightsDelirium features must be clearly defined, standardized, and operationalized.Large datasets incorporating both clinical and biomarker variables should be analyzed together.Delirium screening should incorporate communication and reasoning. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
653 | a acute encephalopathy | |
653 | a biomarkers | |
653 | a clinical features | |
653 | a cognitive change | |
653 | a delirium | |
653 | a endotype | |
653 | a subphenotype | |
653 | a subtype | |
700 | 1 | a Brummel, N. E.4 aut |
700 | 1 | a Caplan, G. A.4 aut |
700 | 1 | a Cunningham, C.4 aut |
700 | 1 | a Evered, L. A.4 aut |
700 | 1 | a Fiest, K. M.4 aut |
700 | 1 | a Girard, T. D.4 aut |
700 | 1 | a Jackson, T. A.4 aut |
700 | 1 | a LaHue, S. C.4 aut |
700 | 1 | a Lindroth, H. L.4 aut |
700 | 1 | a Maclullich, A. M. J.4 aut |
700 | 1 | a McAuley, D. F.4 aut |
700 | 1 | a Oh, E. S.4 aut |
700 | 1 | a Oldham, M. A.4 aut |
700 | 1 | a Page, V. J.4 aut |
700 | 1 | a Pandharipande, P. P.4 aut |
700 | 1 | a Potter, K. M.4 aut |
700 | 1 | a Sinha, P.4 aut |
700 | 1 | a Slooter, A. J. C.4 aut |
700 | 1 | a Sweeney, A. M.4 aut |
700 | 1 | a Tieges, Z.4 aut |
700 | 1 | a Van Dellen, E.4 aut |
700 | 1 | a Wilcox, M. E.4 aut |
700 | 1 | a Zetterberg, Henrik,d 1973u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xzethe |
700 | 1 | a Cunningham, E. L.4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi4 org |
773 | 0 | t Alzheimers & Dementiag 20:1, s. 183-194q 20:1<183-194x 1552-5260 |
856 | 4 8 | u https://gup.ub.gu.se/publication/328852 |
856 | 4 8 | u https://doi.org/10.1002/alz.13419 |
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