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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006547naa a2200637 4500
001oai:DiVA.org:liu-125684
003SwePub
008160229s2016 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:132921832
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1256842 URI
0247 a https://doi.org/10.1371/journal.pone.01475442 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1329218322 URI
040 a (SwePub)liud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Phu, Vu Dinhu Natl Hosp Trop Dis, Intens Care Unit, Hanoi, Vietnam4 aut
2451 0a Burden of Hospital Acquired Infections and Antimicrobial Use in Vietnamese Adult Intensive Care Units
264 c 2016-01-29
264 1b PUBLIC LIBRARY SCIENCE,c 2016
338 a electronic2 rdacarrier
520 a Background Vietnam is a lower middle-income country with no national surveillance system for hospital-acquired infections (HAIs). We assessed the prevalence of hospital-acquired infections and antimicrobial use in adult intensive care units (ICUs) across Vietnam. Methods Monthly repeated point prevalence surveys were systematically conducted to assess HAI prevalence and antimicrobial use in 15 adult ICUs across Vietnam. Adults admitted to participating ICUs before 08: 00 a.m. on the survey day were included. Results Among 3287 patients enrolled, the HAI prevalence was 29.5% (965/3266 patients, 21 missing). Pneumonia accounted for 79.4% (804/1012) of HAIs Most HAIs (84.5% [855/1012]) were acquired in the survey hospital with 42.5% (363/855) acquired prior to ICU admission and 57.5% (492/855) developed during ICU admission. In multivariate analysis, the strongest risk factors for HAI acquired in ICU were: intubation (OR 2.76), urinary catheter (OR 2.12), no involvement of a family member in patient care (OR 1.94), and surgery after admission (OR 1.66). 726 bacterial isolates were cultured from 622/1012 HAIs, most frequently Acinetobacter baumannii (177/726 [24.4%]), Pseudomonas aeruginosa (100/726 [13.8%]), and Klebsiella pneumoniae (84/726 [11.6%]), with carbapenem resistance rates of 89.2%, 55.7%, and 14.9% respectively. Antimicrobials were prescribed for 84.8% (2787/ 3287) patients, with 73.7% of patients receiving two or more. The most common antimicrobial groups were third generation cephalosporins, fluoroquinolones, and carbapenems (20.1%, 19.4%, and 14.1% of total antimicrobials, respectively). Conclusion A high prevalence of HAIs was observed, mainly caused by Gram-negative bacteria with high carbapenem resistance rates. This in combination with a high rate of antimicrobial use illustrates the urgent need to improve rational antimicrobial use and infection control efforts.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng
7001 a Wertheim, Heiman FLu Univ Oxford, Clin Res Unit, Wellcome Trust Major Overseas Programme, Hanoi, Vietnam; Univ Oxford, Nuffield Dept Clin Med, Ctr Trop Med, Oxford OX1 2JD, England4 aut
7001 a Larsson, Mattiasu Karolinska Institutet,Karolinska Institute, Sweden4 aut
7001 a Nadjm, Behzadu University of Oxford, England4 aut
7001 a Dinh, Quynh-Daou Univ Oxford, Clin Res Unit, Wellcome Trust Major Overseas Programme, Hanoi, Vietnam4 aut
7001 a Nilsson, Lennart Eu Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)lenni43
7001 a Rydell, Ulfu Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Hälsouniversitetet4 aut0 (Swepub:liu)ulfry79
7001 a Le, Tuyet Thi Diemu Bach Mai Hosp, Intens Care Unit, Hanoi, Vietnam4 aut
7001 a Trinh, Son Hongu Viet Duc Hosp, Board Directors, Hanoi, Vietnam4 aut
7001 a Pham, Hung Minhu St Paul Hosp, Pharm, Hanoi, Vietnam4 aut
7001 a Tran, Cang Thanhu Viet Tiep Hosp, Intens Care, Hai Phong, Vietnam4 aut
7001 a Doan, Hanh Thi Hongu Vietnam Sweden Uong Bi Hosp, Board Directors, Quang Ninh, Vietnam4 aut
7001 a Tran, Nguyen Thuau Hue Cent Gen Hosp, Dept Gen Internal Med & Geriatr, Hue, Vietnam4 aut
7001 a Le, Nhan Ducu Da Nang Hosp, Board Directors, Da Nang, Vietnam4 aut
7001 a Van Huynh, Nhuanu Binh Dinh Hosp, Infect Dept, Binh Dinh, Vietnam4 aut
7001 a Tran, Thao Phuongu Khanh Hoa Hosp, Intens Care Unit, Khanh Hoa, Vietnam4 aut
7001 a Tran, Bao Ducu Dak Lak Hosp, Planning Dept, Dak Lak, Vietnam4 aut
7001 a Nguyen, Son Truongu Cho Ray Hosp, Board Directors, Ho Chi Minh City, Vietnam4 aut
7001 a Pham, Thao Thi Ngocu Cho Ray Hosp, Board Directors, Ho Chi Minh City, Vietnam4 aut
7001 a Dang, Tam Quangu Can Tho Cent Gen Hosptial, Board Directors, Can Tho, Vietnam4 aut
7001 a Nguyen, Chau Van Vinhu Hosp Trop Dis, Board Directors, Ho Chi Minh City, Vietnam,Natl Hosp Trop Dis, Board Directors, Hanoi, Vietnam4 aut
7001 a Lam, Yen Minhu Hosp Trop Dis, Board Directors, Ho Chi Minh City, Vietnam4 aut
7001 a Thwaites, Guyu Univ Oxford, Nuffield Dept Clin Med, Ctr Trop Med, Oxford OX1 2JD, England; Univ Oxford, Clin Res Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam4 aut
7001 a Van Nguyen, Kinhu Natl Hosp Trop Dis, Board Directors, Hanoi, Vietnam4 aut
7001 a Hanberger, Håkanu Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland4 aut0 (Swepub:liu)hakha84
7102 a Natl Hosp Trop Dis, Intens Care Unit, Hanoi, Vietnamb Univ Oxford, Clin Res Unit, Wellcome Trust Major Overseas Programme, Hanoi, Vietnam; Univ Oxford, Nuffield Dept Clin Med, Ctr Trop Med, Oxford OX1 2JD, England4 org
7730 t PLOS ONEd : PUBLIC LIBRARY SCIENCEg 11:1q 11:1x 1932-6203
8564 u https://liu.diva-portal.org/smash/get/diva2:908705/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0147544&type=printable
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-125684
8564 8u https://doi.org/10.1371/journal.pone.0147544
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:132921832

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