EndoVAscular treatment and ThRombolysis for Ischemic Stroke Patients (EVA-TRISP) registry: basis and methodology of a pan-European prospective ischaemic stroke revascularisation treatment registry.

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Nordanstig, Annika,1974Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience (author)

EndoVAscular treatment and ThRombolysis for Ischemic Stroke Patients (EVA-TRISP) registry: basis and methodology of a pan-European prospective ischaemic stroke revascularisation treatment registry.

Article/chapterEnglish2021

Publisher, publication year, extent ...

2021-08-09
BMJ,2021

Numbers

LIBRIS-ID:oai:gup.ub.gu.se/306858
https://gup.ub.gu.se/publication/306858URI
https://doi.org/10.1136/bmjopen-2020-042211DOI

Supplementary language notes

Language:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

The Thrombolysis in Ischemic Stroke Patients (TRISP) collaboration was a concerted effort initiated in 2010 with the purpose to address relevant research questions about the effectiveness and safety of intravenous thrombolysis (IVT). The collaboration also aims to prospectively collect data on patients undergoing endovascular treatment (EVT) and hence the name of the collaboration was changed from TRISP to EVA-TRISP. The methodology of the former TRISP registry for patients treated with IVT has already been published. This paper focuses on describing the EVT part of the registry.All centres committed to collecting predefined variables on consecutive patients prospectively. We aim for accuracy and completeness of the data and to adapt local databases to investigate novel research questions. Herein, we introduce the methodology of a recently constructed academic investigator-initiated open collaboration EVT registry built as an extension of an existing IVT registry in patients with acute ischaemic stroke (AIS).Currently, the EVA-TRISP network includes 20 stroke centres with considerable expertise in EVT and maintenance of high-quality hospital-based registries. Following several successful randomised controlled trials (RCTs), many important clinical questions remain unanswered in the (EVT) field and some of them will unlikely be investigated in future RCTs. Prospective registries with high-quality data on EVT-treated patients may help answering some of these unanswered issues, especially on safety and efficacy of EVT in specific patient subgroups.This collaborative effort aims at addressing clinically important questions on safety and efficacy of EVT in conditions not covered by RCTs. The TRISP registry generated substantial novel data supporting stroke physicians in their daily decision making considering IVT candidate patients. While providing observational data on EVT in daily clinical practice, our future findings may likewise be hypothesis generating for future research as well as for quality improvement (on EVT). The collaboration welcomes participation of further centres willing to fulfill the commitment and the outlined requirements.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
Brain Ischemia
drug therapy
Endovascular Procedures
Extravehicular Activity
Fibrinolytic Agents
therapeutic use
Humans
Ischemic Stroke
Registries
Stroke
drug therapy
Thrombectomy
Thrombolytic Therapy
Treatment Outcome

Added entries (persons, corporate bodies, meetings, titles ...)

Curtze, Sami (author)
Gensicke, Henrik (author)
Zinkstok, Sanne M (author)
Erdur, Hebun (author)
Karlsson, Camilla,1977Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience(Swepub:gu)xkarca (author)
Karlsson, Jan-Erik,1960Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience (author)
Martinez-Majander, Nicolas (author)
Sibolt, Gerli (author)
Lyrer, Philippe (author)
Traenka, Christopher (author)
Baharoglu, Merih I (author)
Scheitz, Jan F (author)
Bricout, Nicolas (author)
Hénon, Hilde (author)
Leys, Didier (author)
Eskandari, Ashraf (author)
Michel, Patrik (author)
Hametner, Christian (author)
Ringleb, Peter Arthur (author)
Arnold, Marcel (author)
Fischer, Urs (author)
Sarikaya, Hakan (author)
Seiffge, David J (author)
Pezzini, Alessandro (author)
Zini, Andrea (author)
Padjen, Visnja (author)
Jovanovic, Dejana R (author)
Luft, Andreas (author)
Wegener, Susanne (author)
Kellert, Lars (author)
Feil, Katharina (author)
Kägi, Georg (author)
Rentzos, Alexandros,1979Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology(Swepub:gu)xrenta (author)
Lappalainen, Kimmo (author)
Leker, Ronen R (author)
Cohen, Jose E (author)
Gomori, John (author)
Brehm, Alex (author)
Liman, Jan (author)
Psychogios, Marios (author)
Kastrup, Andreas (author)
Papanagiotou, Panagiotis (author)
Gralla, Jan (author)
Magoni, Mauro (author)
Majoie, Charles B L M (author)
Bohner, Georg (author)
Vukasinovic, Ivan (author)
Cvetic, Vladimir (author)
Weber, Johannes (author)
Kulcsar, Zsolt (author)
Bendszus, Martin (author)
Möhlenbruch, Markus (author)
Ntaios, George (author)
Kapsalaki, Eftychia (author)
Jood, Katarina,1966Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience(Swepub:gu)xjooka (author)
Nolte, Christian H (author)
Nederkoorn, Paul J J (author)
Engelter, Stefan (author)
Strbian, Daniel (author)
Tatlisumak, Turgut (author)
Göteborgs universitetInstitutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap (creator_code:org_t)

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By the author/editor: Nordanstig, Anni ...; Curtze, Sami; Gensicke, Henrik; Zinkstok, Sanne ...; Erdur, Hebun; Karlsson, Camill ...; show more...; Karlsson, Jan-Er ...; Martinez-Majande ...; Sibolt, Gerli; Lyrer, Philippe; Traenka, Christo ...; Baharoglu, Merih ...; Scheitz, Jan F; Bricout, Nicolas; Hénon, Hilde; Leys, Didier; Eskandari, Ashra ...; Michel, Patrik; Hametner, Christ ...; Ringleb, Peter A ...; Arnold, Marcel; Fischer, Urs; Sarikaya, Hakan; Seiffge, David J; Pezzini, Alessan ...; Zini, Andrea; Padjen, Visnja; Jovanovic, Dejan ...; Luft, Andreas; Wegener, Susanne; Kellert, Lars; Feil, Katharina; Kägi, Georg; Rentzos, Alexand ...; Lappalainen, Kim ...; Leker, Ronen R; Cohen, Jose E; Gomori, John; Brehm, Alex; Liman, Jan; Psychogios, Mari ...; Kastrup, Andreas; Papanagiotou, Pa ...; Gralla, Jan; Magoni, Mauro; Majoie, Charles ...; Bohner, Georg; Vukasinovic, Iva ...; Cvetic, Vladimir; Weber, Johannes; Kulcsar, Zsolt; Bendszus, Martin; Möhlenbruch, Mar ...; Ntaios, George; Kapsalaki, Eftyc ...; Jood, Katarina, ...; Nolte, Christian ...; Nederkoorn, Paul ...; Engelter, Stefan; Strbian, Daniel; Tatlisumak, Turg ...; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Neurology

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Radiology Nuclea ...

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