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High prevalence of ...
High prevalence of persistent symptoms and reduced health-related quality of life 6 months after COVID-19
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- Ahmad, Irma (författare)
- Department of Infectious Diseases, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Department of Radiation Oncology, Stanford University, Stanford, CA, United States,Örebro Univ, Fac Med & Hlth, Dept Infect Dis, Örebro, Sweden.
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- Edin, Alicia, 1985- (författare)
- Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.
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- Granvik, Christoffer (författare)
- Umeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.
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- Kumm Persson, Lowa (författare)
- Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.
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- Tevell, Staffan, 1975- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Infectious Diseases, Karlstad Hospital, Karlstad, Sweden; Centre for Clinical Research and Education, Region Värmland, Karlstad, Sweden; School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Karlstad Hosp, Dept Infect Dis, Karlstad, Sweden.;Ctr Clin Res & Educ, Karlstad, Sweden.;Örebro Univ, Fac Med & Hlth, Sch Med Sci, Örebro, Sweden.
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- Månsson, Emeli (författare)
- Uppsala universitet,Centrum för klinisk forskning, Västerås
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- Magnuson, Anders (författare)
- Center for Clinical Epidemiology and Biostatistics, Faculty of Medicine and Health, School of Medical Sciences, Örebro University, Örebro, Sweden,Örebro Univ, Fac Med & Hlth, Ctr Clin Epidemiol & Biostat, Sch Med Sci, Örebro, Sweden.
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- Marklund, Ingela (författare)
- Umeå universitet,Institutionen för samhällsmedicin och rehabilitering,Centre for Clinical Research and Education, Region Värmland, Karlstad, Sweden,Ctr Clin Res & Educ, Karlstad, Sweden.;Umeå Univ, Dept Community Med & Rehabil, Umeå, Sweden.
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- Persson, Ida-Lisa (författare)
- Umeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.
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- Kauppi, Anna (författare)
- Umeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.
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- Ahlm, Clas, 1956- (författare)
- Umeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.
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- Forsell, Mattias N. E. (författare)
- Umeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.
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- Sundh, Josefin, 1972- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Respiratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Örebro Univ, Fac Med & Hlth, Dept Resp Med, Örebro, Sweden.
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- Lange, Anna, 1975- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Infectious Diseases,Department of Radiation Oncology, Stanford University, Stanford, CA, United States,Örebro Univ, Fac Med & Hlth, Dept Infect Dis, Örebro, Sweden.
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- Cajander, Sara, 1980- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Infectious Diseases, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Department of Radiation Oncology, Stanford University, Stanford, CA, United States,Örebro Univ, Fac Med & Hlth, Dept Infect Dis, Örebro, Sweden.
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- Normark, Johan (författare)
- Umeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.
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(creator_code:org_t)
- 2023-02-02
- 2023
- Engelska.
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Ingår i: Frontiers in Public Health. - : Frontiers Media S.A.. - 2296-2565. ; 11
- Relaterad länk:
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https://doi.org/10.3...
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https://umu.diva-por... (primary) (Raw object)
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- BACKGROUND: The long-term sequelae after COVID-19 constitute a challenge to public health and increased knowledge is needed. We investigated the prevalence of self-reported persistent symptoms and reduced health-related quality of life (HRQoL) in relation to functional exercise capacity, 6 months after infection, and explored risk factors for COVID-19 sequalae.METHODS: This was a prospective, multicenter, cohort study including 434 patients. At 6 months, physical exercise capacity was assessed by a 1-minute sit-to-stand test (1MSTST) and persistent symptoms were reported and HRQoL was evaluated through the EuroQol 5-level 5-dimension (EQ-5D-5L) questionnaire. Patients with both persistent symptoms and reduced HRQoL were classified into a new definition of post-acute COVID syndrome, PACS+. Risk factors for developing persistent symptoms, reduced HRQoL and PACS+ were identified by multivariable Poisson regression.RESULTS: Persistent symptoms were experienced by 79% of hospitalized, and 59% of non-hospitalized patients at 6 months. Hospitalized patients had a higher prevalence of self-assessed reduced overall health (28 vs. 12%) and PACS+ (31 vs. 11%). PACS+ was associated with reduced exercise capacity but not with abnormal pulse/desaturation during 1MSTST. Hospitalization was the most important independent risk factor for developing persistent symptoms, reduced overall health and PACS+.CONCLUSION: Persistent symptoms and reduced HRQoL are common among COVID-19 survivors, but abnormal pulse and peripheral saturation during exercise could not distinguish patients with PACS+. Patients with severe infection requiring hospitalization were more likely to develop PACS+, hence these patients should be prioritized for clinical follow-up after COVID-19.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- COVID-19
- EQ-5D
- PACS
- Post COVID-19 condition (PCC)
- SARS-CoV-2
- long-COVID
- post-acute COVID syndrome (PACS)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Ahmad, Irma
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Edin, Alicia, 19 ...
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Granvik, Christo ...
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Kumm Persson, Lo ...
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Tevell, Staffan, ...
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Månsson, Emeli
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Magnuson, Anders
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Marklund, Ingela
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Persson, Ida-Lis ...
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Kauppi, Anna
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Ahlm, Clas, 1956 ...
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Forsell, Mattias ...
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Sundh, Josefin, ...
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Lange, Anna, 197 ...
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Cajander, Sara, ...
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Normark, Johan
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- Av lärosätet
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Örebro universitet
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Umeå universitet
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Uppsala universitet