WFRF:(Sandberg Olof)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03974naa a2200361 4500 | |
| 001 | oai:DiVA.org:liu-145120 | |
| 003 | SwePub | |
| 008 | 180219s2018 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1451202 URI |
| 024 | 7 | a https://doi.org/10.1080/17453674.2017.13822802 DOI |
| 040 | a (SwePub)liu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Bernhardsson, Magnusu Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Ortopedkliniken i Linköping4 aut0 (Swepub:liu)magbe94 |
| 245 | 1 0 | a Marrow compartment contribution to cortical defect healing |
| 264 | c 2017-09-26 | |
| 264 | 1 | b TAYLOR & FRANCIS LTD,c 2018 |
| 338 | a electronic2 rdacarrier | |
| 520 | a Background and purpose - Healing of shaft fractures is commonly described as regards external callus. We wanted to clarify the role of the bone marrow compartment in the healing of stable shaft fractures. Patients and methods - A longitudinal furrow was milled along the longitudinal axis of the femoral shaft in mice. The exposed bone marrow under the furrow was scooped out. The mice were then randomized to no further treatment, or to receiving 2 silicone plugs in the medullary canal distal and proximal to the defect. The plugs isolated the remaining marrow from contact with the defect. Results were studied with histology and flow cytometry. Results - Without silicone plugs, the marrow defect was filled with new bone marrow-like tissue by day 5, and new bone was seen already on day 10. The new bone was seen only at the level of the cortical injury, where it seemed to form simultaneously in the entire region of the removed cortex. The new bone seemed not to invade the marrow compartment, and there was a sharp edge between new bone and marrow. The regenerated marrow was similar to uninjured marrow, but contained considerably more cells. In the specimens with plugs, the marrow compartment was either filled with loose scar tissue, or empty, and there was only minimal bone formation, mainly located around the edges of the cortical injury. Interpretation - Marrow regeneration in the defect seemed to be a prerequisite for normal cortical healing. Shaft fracture treatment should perhaps pay more attention to the local bone marrow. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng |
| 700 | 1 | a Tätting, Loveu Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Ortopedkliniken i Linköping4 aut0 (Swepub:liu)lovta16 |
| 700 | 1 | a Sandberg, Olofu Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Ortopedkliniken i Linköping4 aut0 (Swepub:liu)olosa45 |
| 700 | 1 | a Schilcher, Jörgu Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Ortopedkliniken i Linköping4 aut0 (Swepub:liu)jorsc03 |
| 700 | 1 | a Aspenberg, Peru Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Ortopedkliniken i Linköping4 aut0 (Swepub:liu)peras36 |
| 710 | 2 | a Linköpings universitetb Avdelningen för Kirurgi, Ortopedi och Onkologi4 org |
| 773 | 0 | t Acta Orthopaedicad : TAYLOR & FRANCIS LTDg 89:1, s. 119-123q 89:1<119-123x 1745-3674x 1745-3682 |
| 856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1183670/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://www.tandfonline.com/doi/pdf/10.1080/17453674.2017.1382280?needAccess=true |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-145120 |
| 856 | 4 8 | u https://doi.org/10.1080/17453674.2017.1382280 |
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