Suitability of microDiamond detectors for the determination of absorbed dose to water around high-dose-rate Ir-192 brachytherapy sources

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Kaveckyte, VaivaLinköpings universitet,Avdelningen för radiologiska vetenskaper,Medicinska fakulteten (författare)

Suitability of microDiamond detectors for the determination of absorbed dose to water around high-dose-rate Ir-192 brachytherapy sources

Artikel/kapitelEngelska2018

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2017-12-16
WILEY,2018
printrdacarrier

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LIBRIS-ID:oai:DiVA.org:liu-144894
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-144894URI
https://doi.org/10.1002/mp.12694DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:137479411URI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:ref swepub-contenttype
Ämneskategori:art swepub-publicationtype

Anmärkningar

Funding Agencies|Swedish Radiation Safety Authority [SSM 2013-1253]; Swedish Cancer Society (Cancer-fonden) [CAN 2015/618]
Purpose: Experimental dosimetry of high-dose-rate (HDR) Ir-192 brachytherapy (BT) sources is complicated due to high dose and dose-rate gradients, and softening of photon energy spectrum with depth. A single crystal synthetic diamond detector microDiamond (PTW 60019, Freiburg, Germany) has a small active volume, high sensitivity, direct readout, and nearly water-equivalent active volume. The purpose of this study was to evaluate the suitability of microDiamond detectors for the determination of absorbed dose to water around HDR Ir-192 BT sources. Three microDiamond detectors were used, allowing for the comparison of their properties. Methods: In-phantom measurements were performed using microSelectron and VariSource iX HDR Ir-192 BT treatment units. Their treatment planning systems (TPSs), Oncentra (v. 4.3) and BrachyVision (v. 13.6), respectively, were used to create irradiation plans for a cubic PMMA phantom with the microDiamond positioned at one of three source-to-detector distances (SDDs) (1.5, 2.5, and 5.5 cm) at a time. The source was stepped in increments of 0.5 cm over a total length of 6 cm to yield absorbed dose of 2 Gy at the nominal reference-point of the detector. Detectors were calibrated in Co-60 beam in terms of absorbed dose to water, and Monte Carlo (MC) calculated beam quality correction factors were applied to account for absorbed-dose energy dependence. Phantom correction factors were applied to account for differences in dimensions between the measurement phantom and a water phantom used for absorbed dose calculations made with a TPS. The same measurements were made with all three of the detectors. Additionally, dose-rate dependence and stability of the detectors were evaluated in Co-60 beam. Results: The percentage differences between experimentally determined and TPS-calculated absorbed doses to water were from -1.3% to +2.9%. The values agreed to within experimental uncertainties, which were from 1.9% to 4.3% (k = 2) depending on the detector, SDD and treatment delivery unit. No dose-rate or intrinsic energy dependence corrections were applied. All microDiamonds were comparable in terms of preirradiation dose, stability of the readings and energy response, and showed a good agreement. Conclusions: The results indicate that the microDiamond is potentially suitable for the determination of absorbed dose to water around HDR Ir-192 BT sources and may be used for independent verification of TPSs calculations, as well as for QA measurements of HDR Ir-192 BT treatment delivery units at clinical sites. (C) 2017 American Association of Physicists in Medicine

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
brachytherapy; dosimetry; Iridium-192; microDiamond detector; radiation detectors

Biuppslag (personer, institutioner, konferenser, titlar ...)

Malusek, AlexandrLinköpings universitet,Avdelningen för radiologiska vetenskaper,Medicinska fakulteten(Swepub:liu)alema80 (författare)
Benmakhlouf, HamzaKarolinska Univ Hosp, Sweden (författare)
Alm Carlsson, GudrunLinköpings universitet,Avdelningen för radiologiska vetenskaper,Medicinska fakulteten,Region Östergötland, Radiofysikavdelningen US(Swepub:liu)gudal03 (författare)
Carlsson Tedgren, ÅsaKarolinska Institutet,Linköpings universitet,Avdelningen för radiologiska vetenskaper,Medicinska fakulteten,Region Östergötland, Radiofysikavdelningen US(Swepub:liu)asaca90 (författare)
Linköpings universitetAvdelningen för radiologiska vetenskaper (creator_code:org_t)

Sammanhörande titlar

Ingår i:Medical physics (Lancaster): WILEY45:1, s. 429-4370094-24052473-4209

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