An A to U transversion at position 1067 of 23 S rRNA from Escherichia coli impairs EF-Tu and EF-G function

• Escherichia coli ribosomes with an A to U transversion at nucleotide 1067 of their 23 S rRNA are impaired in their effective association rate constants (k(cat)/K-M) for both EF-Tu and EF-G binding. In addition, the times that EF-G and EF-Tu spend on the r

Nyckelord

translation; EF-Tu; EF-G; ribosome kinetics; rRNA; ELONGATION-FACTOR-G; RIBOSOMAL-RNA; PROTEIN-SYNTHESIS; CRYSTAL-STRUCTURE; TERNARY COMPLEX; GTPASE CENTER; P-SITES; TRANSLATION; INVITRO; THIOSTREPTON

Publikations- och innehållstyp

vet (ämneskategori)

art (ämneskategori)