Search: WFRF:(Roberts Christine L) >
HPV antibody levels...
HPV antibody levels and clinical efficacy following administration of a prophylactic quadrivalent HPV vaccine
-
Joura, Elmar A. (author)
-
Kjaer, Susanne K. (author)
-
Wheeler, Cosette M. (author)
-
show more...
-
Sigurdsson, Kristjan (author)
-
Iversene, Ole-Erik (author)
-
Hernandez-Avila, Mauricio (author)
-
Perez, Gonzalo (author)
-
Brown, Darron R. (author)
-
Koutsky, Laura A. (author)
-
Tay, Eng Hseon (author)
-
Garcia, Patricia (author)
-
Ault, Kevin A. (author)
-
Garland, Suzanne M. (author)
-
Leodolter, Sepp (author)
-
Olssonn, Sven-Eric (author)
-
Tang, Grace W. K. (author)
-
Ferris, Daron G. (author)
-
Paavonen, Jorma (author)
-
Lehtinen, Matti (author)
-
Steben, Marc (author)
-
Bosch, Xavier (author)
-
- Dillner, Joakim (author)
- Karolinska Institutet,Lund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups
-
Kurmanv, Robert J. (author)
-
Majewski, Slawomir (author)
-
Munoz, Nubia (author)
-
Myers, Evan R. (author)
-
Villa, Luisa L. (author)
-
Taddeo, Frank J. (author)
-
Roberts, Christine (author)
-
Tadesse, Amha (author)
-
Bryan, Janine (author)
-
Lupinaccia, Lisa C. (author)
-
Giacoletti, Katherine E. D. (author)
-
Lu, Shuang (author)
-
Vuocolo, Scott (author)
-
Hesley, Teresa M. (author)
-
Haupt, Richard M. (author)
-
Barr, Eliav (author)
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2008
- 2008
- English.
-
In: Vaccine. - : Elsevier BV. - 1873-2518 .- 0264-410X. ; 26:52, s. 6844-6851
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- The efficacy of the quadrivalent Human Papillomavirus (HPV) vaccine is thought to be mediated by humoral immunity. We evaluated the correlation between quadrivalent HPV vaccine-induced serum anti-HPV responses and efficacy. 17,622 women were vaccinated at day 1, and months 2 and 6. At day I and at 6-12 months intervals for up to 48 months, subjects underwent Papanicolaou and genital HPV testing. No immune correlate of protection could be found due to low number of cases. Although 40% of vaccine subjects were anti-HPV 18 seronegative at end-of-study, efficacy against HPV 18-related disease remained high (98.4%; 95% CI: 90.5-100.0) despite high attack rates in the placebo group. These results suggest vaccine-induced protection via immune memory, or lower than detectable HPV 18 antibody titers. (C) 2008 Elsevier Ltd. All rights reserved.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
Keyword
- Human Papillomavirus
- Humoral immunity
- Immune memory
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
-
Vaccine
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Joura, Elmar A.
-
Kjaer, Susanne K ...
-
Wheeler, Cosette ...
-
Sigurdsson, Kris ...
-
Iversene, Ole-Er ...
-
Hernandez-Avila, ...
-
show more...
-
Perez, Gonzalo
-
Brown, Darron R.
-
Koutsky, Laura A ...
-
Tay, Eng Hseon
-
Garcia, Patricia
-
Ault, Kevin A.
-
Garland, Suzanne ...
-
Leodolter, Sepp
-
Olssonn, Sven-Er ...
-
Tang, Grace W. K ...
-
Ferris, Daron G.
-
Paavonen, Jorma
-
Lehtinen, Matti
-
Steben, Marc
-
Bosch, Xavier
-
Dillner, Joakim
-
Kurmanv, Robert ...
-
Majewski, Slawom ...
-
Munoz, Nubia
-
Myers, Evan R.
-
Villa, Luisa L.
-
Taddeo, Frank J.
-
Roberts, Christi ...
-
Tadesse, Amha
-
Bryan, Janine
-
Lupinaccia, Lisa ...
-
Giacoletti, Kath ...
-
Lu, Shuang
-
Vuocolo, Scott
-
Hesley, Teresa M ...
-
Haupt, Richard M ...
-
Barr, Eliav
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Microbiology in ...
- Articles in the publication
-
Vaccine
- By the university
-
Lund University
-
Karolinska Institutet