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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005828naa a2200565 4500
001oai:DiVA.org:oru-70799
003SwePub
008181218s2019 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:141280215
009oai:DiVA.org:liu-158935
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-707992 URI
0247 a https://doi.org/10.1093/ibd/izy3822 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1412802152 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1589352 URI
040 a (SwePub)orud (SwePub)kid (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Everhov, Åsa H.u Karolinska Institutet,Karolinska Inst, Sweden4 aut
2451 0a Work Loss Before and After Diagnosis of Crohn's Disease
264 c 2018-12-14
264 1b Oxford University Press,c 2019
338 a print2 rdacarrier
500 a Funding Agencies:Karolinska Institutet (KI SOS)Swedish Medical Society (Fund for Research in Gastroenterology)  Swedish Medical Society (Ihre Foundation)  Stiftelsen Tornspiran  Mag-tarmfonden  Jane and Dan Olsson Foundation  Mjölkdroppen Foundation  Bengt Ihre Research Fellowship in Gastroenterology 
500 a Funding Agencies|Karolinska Institutet (KI SOS); Swedish Research Council; Swedish Cancer Society; Heart Lung Foundation; Swedish Medical Society; Swedish Medical Society (Fund for Research in Gastroenterology); Swedish Medical Society (Ihre Foundation); Stiftelsen Tornspiran; Mag-tarmfonden; Jane and Dan Olsson Foundation; Mjolkdroppen Foundation; Bengt Ihre Research Fellowship in Gastroenterology; Karolinska Institutet; Stockholm County Council
520 a Background: The aim of this study was to examine work loss in patients with Crohn's disease.Methods: Using nationwide registers, we identified incident patients with Crohn's disease (2007-2010) and population comparator subjects without inflammatory bowel disease, matched by age, sex, calendar year, health care region, and education level. We assessed the number of lost workdays due to sick leave and disability pension from 5 years before to 5 years after first diagnosis of Crohn's disease or end of follow-up (September 30, 2015).Results: Among the 2015 incident Crohn's disease patients (median age, 35 years; 50% women), both the proportion with work loss and the mean annual number of lost workdays were larger 5 years before diagnosis (25%; mean, 45 days) than in the 10,067 comparators (17%; mean, 29 days). Increased work loss was seen during the year of diagnosis, after which it declined to levels similar to before diagnosis. Of all patients, 75% had no work loss 24-12 months before diagnosis. Of them, 84% had full work ability also 12-24 months after diagnosis. In patients with total work loss (8.3% of all) before diagnosis, 83% did not work after. Among those with full work ability before diagnosis, the absolute risk of having total work loss after diagnosis was 1.4% (0.43% in the comparators). Our results were consistent across several sensitivity analyses using alternative definitions for date of diagnosis.Conclusions: Patients with Crohn's disease had increased work loss several years before diagnosis, possibly explained by comorbidity or by diagnostic delay.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
653 a Sick leave
653 a disability pension
653 a Crohn’s disease
653 a IBD
653 a diagnostic delay
653 a comorbidity
7001 a Khalili, Hamedu Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Masschusetts, USA,Karolinska Inst, Sweden; Harvard Med Sch, MA 02115 USA4 aut
7001 a Askling, Johanu Karolinska Institutet,Karolinska Inst, Sweden4 aut
7001 a Myrelid, Päru Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US4 aut0 (Swepub:liu)parmy24
7001 a Ludvigsson, Jonas F.,d 1969-u Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Örebro University Hospital, Örebro University, Örebro, Sweden,Karolinska Inst, Sweden; Orebro Univ Hosp, Sweden4 aut0 (Swepub:oru)jsln
7001 a Halfvarson, Jonas,d 1970-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Gastroenterology,Orebro Univ, Sweden4 aut0 (Swepub:oru)jshn
7001 a Nordenvall, Carolineu Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden4 aut
7001 a Neovius, Martinu Karolinska Institutet,Karolinska Inst, Sweden4 aut
7001 a Söderling, Jonasu Karolinska Institutet,Karolinska Inst, Sweden4 aut
7001 a Olén, Olau Karolinska Institutet,Karolinska Inst, Sweden; Sachs Children and Youth Hosp, Sweden4 aut
7102 a Karolinska Institutetb Karolinska Inst, Sweden4 org
7730 t Inflammatory Bowel Diseasesd : Oxford University Pressg 25:7, s. 1237-1247q 25:7<1237-1247x 1078-0998x 1536-4844
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-70799
8564 8u https://doi.org/10.1093/ibd/izy382
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:141280215
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-158935

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