WFRF:(Quintana Murci Lluis)
Sökning: WFRF:(Quintana Murci Lluis) > The risk of COVID-1...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 11386naa a2202761 4500 | |
| 001 | oai:gup.ub.gu.se/317489 | |
| 003 | SwePub | |
| 008 | 240528s2022 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:150513700 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/3174892 URI |
| 024 | 7 | a https://doi.org/10.1073/pnas.22004131192 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1505137002 URI |
| 040 | a (SwePub)gud (SwePub)ki | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Manry, Jérémy4 aut |
| 245 | 1 0 | a The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies. |
| 264 | c 2022-05-16 | |
| 264 | 1 | b Proceedings of the National Academy of Sciences,c 2022 |
| 520 | a Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR) doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ∼20% of deceased patients across age groups, and in ∼1% of individuals aged <70 y and in >4% of those >70 y old in the general population. With a sample of 1,261 unvaccinated deceased patients and 34,159 individuals of the general population sampled before the pandemic, we estimated both IFR and relative risk of death (RRD) across age groups for individuals carrying autoantibodies neutralizing type I IFNs, relative to noncarriers. The RRD associated with any combination of autoantibodies was higher in subjects under 70 y old. For autoantibodies neutralizing IFN-α2 or IFN-ω, the RRDs were 17.0 (95% CI: 11.7 to 24.7) and 5.8 (4.5 to 7.4) for individuals <70 y and ≥70 y old, respectively, whereas, for autoantibodies neutralizing both molecules, the RRDs were 188.3 (44.8 to 774.4) and 7.2 (5.0 to 10.3), respectively. In contrast, IFRs increased with age, ranging from 0.17% (0.12 to 0.31) for individuals <40 y old to 26.7% (20.3 to 35.2) for those ≥80 y old for autoantibodies neutralizing IFN-α2 or IFN-ω, and from 0.84% (0.31 to 8.28) to 40.5% (27.82 to 61.20) for autoantibodies neutralizing both. Autoantibodies against type I IFNs increase IFRs, and are associated with high RRDs, especially when neutralizing both IFN-α2 and IFN-ω. Remarkably, IFRs increase with age, whereas RRDs decrease with age. Autoimmunity to type I IFNs is a strong and common predictor of COVID-19 death. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng |
| 653 | a Adult | |
| 653 | a Age Factors | |
| 653 | a Aged | |
| 653 | a Aged | |
| 653 | a 80 and over | |
| 653 | a Antibodies | |
| 653 | a Neutralizing | |
| 653 | a blood | |
| 653 | a Autoantibodies | |
| 653 | a blood | |
| 653 | a Autoimmunity | |
| 653 | a COVID-19 | |
| 653 | a immunology | |
| 653 | a mortality | |
| 653 | a Female | |
| 653 | a Humans | |
| 653 | a Interferon Type I | |
| 653 | a immunology | |
| 653 | a Male | |
| 653 | a Middle Aged | |
| 653 | a Risk | |
| 653 | a SARS-CoV-2 | |
| 700 | 1 | a Bastard, Paul4 aut |
| 700 | 1 | a Gervais, Adrian4 aut |
| 700 | 1 | a Le Voyer, Tom4 aut |
| 700 | 1 | a Rosain, Jérémie4 aut |
| 700 | 1 | a Philippot, Quentin4 aut |
| 700 | 1 | a Michailidis, Eleftherios4 aut |
| 700 | 1 | a Hoffmann, Hans-Heinrich4 aut |
| 700 | 1 | a Eto, Shohei4 aut |
| 700 | 1 | a Garcia-Prat, Marina4 aut |
| 700 | 1 | a Bizien, Lucy4 aut |
| 700 | 1 | a Parra-Martínez, Alba4 aut |
| 700 | 1 | a Yang, Rui4 aut |
| 700 | 1 | a Haljasmägi, Liis4 aut |
| 700 | 1 | a Migaud, Mélanie4 aut |
| 700 | 1 | a Särekannu, Karita4 aut |
| 700 | 1 | a Maslovskaja, Julia4 aut |
| 700 | 1 | a de Prost, Nicolas4 aut |
| 700 | 1 | a Tandjaoui-Lambiotte, Yacine4 aut |
| 700 | 1 | a Luyt, Charles-Edouard4 aut |
| 700 | 1 | a Amador-Borrero, Blanca4 aut |
| 700 | 1 | a Gaudet, Alexandre4 aut |
| 700 | 1 | a Poissy, Julien4 aut |
| 700 | 1 | a Morel, Pascal4 aut |
| 700 | 1 | a Richard, Pascale4 aut |
| 700 | 1 | a Cognasse, Fabrice4 aut |
| 700 | 1 | a Troya, Jesús4 aut |
| 700 | 1 | a Trouillet-Assant, Sophie4 aut |
| 700 | 1 | a Belot, Alexandre4 aut |
| 700 | 1 | a Saker, Kahina4 aut |
| 700 | 1 | a Garçon, Pierre4 aut |
| 700 | 1 | a Rivière, Jacques G4 aut |
| 700 | 1 | a Lagier, Jean-Christophe4 aut |
| 700 | 1 | a Gentile, Stéphanie4 aut |
| 700 | 1 | a Rosen, Lindsey B4 aut |
| 700 | 1 | a Shaw, Elana4 aut |
| 700 | 1 | a Morio, Tomohiro4 aut |
| 700 | 1 | a Tanaka, Junko4 aut |
| 700 | 1 | a Dalmau, David4 aut |
| 700 | 1 | a Tharaux, Pierre-Louis4 aut |
| 700 | 1 | a Sene, Damien4 aut |
| 700 | 1 | a Stepanian, Alain4 aut |
| 700 | 1 | a Mégarbane, Bruno4 aut |
| 700 | 1 | a Triantafyllia, Vasiliki4 aut |
| 700 | 1 | a Fekkar, Arnaud4 aut |
| 700 | 1 | a Heath, James R4 aut |
| 700 | 1 | a Franco, José Luis4 aut |
| 700 | 1 | a Anaya, Juan-Manuel4 aut |
| 700 | 1 | a Solé-Violán, Jordi4 aut |
| 700 | 1 | a Imberti, Luisa4 aut |
| 700 | 1 | a Biondi, Andrea4 aut |
| 700 | 1 | a Bonfanti, Paolo4 aut |
| 700 | 1 | a Castagnoli, Riccardo4 aut |
| 700 | 1 | a Delmonte, Ottavia M4 aut |
| 700 | 1 | a Zhang, Yu4 aut |
| 700 | 1 | a Snow, Andrew L4 aut |
| 700 | 1 | a Holland, Steven M4 aut |
| 700 | 1 | a Biggs, Catherine M4 aut |
| 700 | 1 | a Moncada-Vélez, Marcela4 aut |
| 700 | 1 | a Arias, Andrés Augusto4 aut |
| 700 | 1 | a Lorenzo, Lazarou Karolinska Institutet4 aut |
| 700 | 1 | a Boucherit, Soraya4 aut |
| 700 | 1 | a Anglicheau, Dany4 aut |
| 700 | 1 | a Planas, Anna M4 aut |
| 700 | 1 | a Haerynck, Filomeen4 aut |
| 700 | 1 | a Duvlis, Sotirija4 aut |
| 700 | 1 | a Ozcelik, Tayfun4 aut |
| 700 | 1 | a Keles, Sevgi4 aut |
| 700 | 1 | a Bousfiha, Ahmed A4 aut |
| 700 | 1 | a El Bakkouri, Jalila4 aut |
| 700 | 1 | a Ramirez-Santana, Carolina4 aut |
| 700 | 1 | a Paul, Stéphane4 aut |
| 700 | 1 | a Pan-Hammarström, Qiangu Karolinska Institutet4 aut |
| 700 | 1 | a Hammarström, Lennart4 aut |
| 700 | 1 | a Dupont, Annabelle4 aut |
| 700 | 1 | a Kurolap, Alina4 aut |
| 700 | 1 | a Metz, Christine N4 aut |
| 700 | 1 | a Aiuti, Alessandro4 aut |
| 700 | 1 | a Casari, Giorgio4 aut |
| 700 | 1 | a Lampasona, Vito4 aut |
| 700 | 1 | a Ciceri, Fabio4 aut |
| 700 | 1 | a Barreiros, Lucila A4 aut |
| 700 | 1 | a Dominguez-Garrido, Elena4 aut |
| 700 | 1 | a Vidigal, Mateus4 aut |
| 700 | 1 | a Zatz, Mayana4 aut |
| 700 | 1 | a van de Beek, Diederik4 aut |
| 700 | 1 | a Sahanic, Sabina4 aut |
| 700 | 1 | a Tancevski, Ivan4 aut |
| 700 | 1 | a Stepanovskyy, Yurii4 aut |
| 700 | 1 | a Boyarchuk, Oksana4 aut |
| 700 | 1 | a Nukui, Yoko4 aut |
| 700 | 1 | a Tsumura, Miyuki4 aut |
| 700 | 1 | a Vidaur, Loreto4 aut |
| 700 | 1 | a Tangye, Stuart G4 aut |
| 700 | 1 | a Burrel, Sonia4 aut |
| 700 | 1 | a Duffy, Darragh4 aut |
| 700 | 1 | a Quintana-Murci, Lluis4 aut |
| 700 | 1 | a Klocperk, Adam4 aut |
| 700 | 1 | a Kann, Nelli Y4 aut |
| 700 | 1 | a Shcherbina, Anna4 aut |
| 700 | 1 | a Lau, Yu-Lung4 aut |
| 700 | 1 | a Leung, Daniel4 aut |
| 700 | 1 | a Coulongeat, Matthieu4 aut |
| 700 | 1 | a Marlet, Julien4 aut |
| 700 | 1 | a Koning, Rutger4 aut |
| 700 | 1 | a Reyes, Luis Felipe4 aut |
| 700 | 1 | a Chauvineau-Grenier, Angélique4 aut |
| 700 | 1 | a Venet, Fabienne4 aut |
| 700 | 1 | a Monneret, Guillaume4 aut |
| 700 | 1 | a Nussenzweig, Michel C4 aut |
| 700 | 1 | a Arrestier, Romain4 aut |
| 700 | 1 | a Boudhabhay, Idris4 aut |
| 700 | 1 | a Baris-Feldman, Hagit4 aut |
| 700 | 1 | a Hagin, David4 aut |
| 700 | 1 | a Wauters, Joost4 aut |
| 700 | 1 | a Meyts, Isabelle4 aut |
| 700 | 1 | a Dyer, Adam H4 aut |
| 700 | 1 | a Kennelly, Sean P4 aut |
| 700 | 1 | a Bourke, Nollaig M4 aut |
| 700 | 1 | a Halwani, Rabih4 aut |
| 700 | 1 | a Sharif-Askari, Fatemeh Saheb4 aut |
| 700 | 1 | a Dorgham, Karim4 aut |
| 700 | 1 | a Sallette, Jérôme4 aut |
| 700 | 1 | a Sedkaoui, Souad Mehlal4 aut |
| 700 | 1 | a AlKhater, Suzan4 aut |
| 700 | 1 | a Rigo-Bonnin, Raúl4 aut |
| 700 | 1 | a Morandeira, Francisco4 aut |
| 700 | 1 | a Roussel, Lucie4 aut |
| 700 | 1 | a Vinh, Donald C4 aut |
| 700 | 1 | a Erikstrup, Christian4 aut |
| 700 | 1 | a Condino-Neto, Antonio4 aut |
| 700 | 1 | a Prando, Carolina4 aut |
| 700 | 1 | a Bondarenko, Anastasiia4 aut |
| 700 | 1 | a Spaan, András N4 aut |
| 700 | 1 | a Gilardin, Laurent4 aut |
| 700 | 1 | a Fellay, Jacques4 aut |
| 700 | 1 | a Lyonnet, Stanislas4 aut |
| 700 | 1 | a Bilguvar, Kaya4 aut |
| 700 | 1 | a Lifton, Richard P4 aut |
| 700 | 1 | a Mane, Shrikant4 aut |
| 700 | 1 | a Ekwall, Olov,d 1968u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Medicine, Department of Rheumatology and Inflammation Research,Institute of Clinical Sciences, Department of Pediatrics4 aut0 (Swepub:gu)xekwol |
| 700 | 1 | a Anderson, Mark S4 aut |
| 700 | 1 | a Boisson, Bertrand4 aut |
| 700 | 1 | a Béziat, Vivien4 aut |
| 700 | 1 | a Zhang, Shen-Ying4 aut |
| 700 | 1 | a Andreakos, Evangelos4 aut |
| 700 | 1 | a Hermine, Olivier4 aut |
| 700 | 1 | a Pujol, Aurora4 aut |
| 700 | 1 | a Peterson, Pärt4 aut |
| 700 | 1 | a Mogensen, Trine H4 aut |
| 700 | 1 | a Rowen, Lee4 aut |
| 700 | 1 | a Mond, James4 aut |
| 700 | 1 | a Debette, Stéphanie4 aut |
| 700 | 1 | a de Lamballerie, Xavier4 aut |
| 700 | 1 | a Burdet, Charles4 aut |
| 700 | 1 | a Bouadma, Lila4 aut |
| 700 | 1 | a Zins, Marie4 aut |
| 700 | 1 | a Soler-Palacin, Pere4 aut |
| 700 | 1 | a Colobran, Roger4 aut |
| 700 | 1 | a Gorochov, Guy4 aut |
| 700 | 1 | a Solanich, Xavier4 aut |
| 700 | 1 | a Susen, Sophie4 aut |
| 700 | 1 | a Martinez-Picado, Javier4 aut |
| 700 | 1 | a Raoult, Didier4 aut |
| 700 | 1 | a Vasse, Marc4 aut |
| 700 | 1 | a Gregersen, Peter K4 aut |
| 700 | 1 | a Piemonti, Lorenzo4 aut |
| 700 | 1 | a Rodríguez-Gallego, Carlos4 aut |
| 700 | 1 | a Notarangelo, Luigi D4 aut |
| 700 | 1 | a Su, Helen C4 aut |
| 700 | 1 | a Kisand, Kai4 aut |
| 700 | 1 | a Okada, Satoshi4 aut |
| 700 | 1 | a Puel, Anne4 aut |
| 700 | 1 | a Jouanguy, Emmanuelle4 aut |
| 700 | 1 | a Rice, Charles M4 aut |
| 700 | 1 | a Tiberghien, Pierre4 aut |
| 700 | 1 | a Zhang, Qian4 aut |
| 700 | 1 | a Casanova, Jean-Laurent4 aut |
| 700 | 1 | a Abel, Laurent4 aut |
| 700 | 1 | a Cobat, Aurélie4 aut |
| 710 | 2 | a Karolinska Institutetb Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning4 org |
| 773 | 0 | t Proceedings of the National Academy of Sciences of the United States of Americad : Proceedings of the National Academy of Sciencesg 119:21q 119:21x 1091-6490 |
| 773 | 0 | t Proceedings of the National Academy of Sciencesd : Proceedings of the National Academy of Sciencesg 119:21q 119:21x 0027-8424 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/317489 |
| 856 | 4 8 | u https://doi.org/10.1073/pnas.2200413119 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:150513700 |
Hitta via bibliotek
- Proceedings of the National Academy of Sciences of the United States of America (Sök värdpublikationen i LIBRIS)
Till lärosätets databas
Hitta mer i SwePub
- Av författaren/redakt...
- Manry, Jérémy
- Bastard, Paul
- Gervais, Adrian
- Le Voyer, Tom
- Rosain, Jérémie
- Philippot, Quent ...
- visa fler...
- Michailidis, Ele ...
- Hoffmann, Hans-H ...
- Eto, Shohei
- Garcia-Prat, Mar ...
- Bizien, Lucy
- Parra-Martínez, ...
- Yang, Rui
- Haljasmägi, Liis
- Migaud, Mélanie
- Särekannu, Karit ...
- Maslovskaja, Jul ...
- de Prost, Nicola ...
- Tandjaoui-Lambio ...
- Luyt, Charles-Ed ...
- Amador-Borrero, ...
- Gaudet, Alexandr ...
- Poissy, Julien
- Morel, Pascal
- Richard, Pascale
- Cognasse, Fabric ...
- Troya, Jesús
- Trouillet-Assant ...
- Belot, Alexandre
- Saker, Kahina
- Garçon, Pierre
- Rivière, Jacques ...
- Lagier, Jean-Chr ...
- Gentile, Stéphan ...
- Rosen, Lindsey B
- Shaw, Elana
- Morio, Tomohiro
- Tanaka, Junko
- Dalmau, David
- Tharaux, Pierre- ...
- Sene, Damien
- Stepanian, Alain
- Mégarbane, Bruno
- Triantafyllia, V ...
- Fekkar, Arnaud
- Heath, James R
- Franco, José Lui ...
- Anaya, Juan-Manu ...
- Solé-Violán, Jor ...
- Imberti, Luisa
- Biondi, Andrea
- Bonfanti, Paolo
- Castagnoli, Ricc ...
- Delmonte, Ottavi ...
- Zhang, Yu
- Snow, Andrew L
- Holland, Steven ...
- Biggs, Catherine ...
- Moncada-Vélez, M ...
- Arias, Andrés Au ...
- Lorenzo, Lazaro
- Boucherit, Soray ...
- Anglicheau, Dany
- Planas, Anna M
- Haerynck, Filome ...
- Duvlis, Sotirija
- Ozcelik, Tayfun
- Keles, Sevgi
- Bousfiha, Ahmed ...
- El Bakkouri, Jal ...
- Ramirez-Santana, ...
- Paul, Stéphane
- Pan-Hammarström, ...
- Hammarström, Len ...
- Dupont, Annabell ...
- Kurolap, Alina
- Metz, Christine ...
- Aiuti, Alessandr ...
- Casari, Giorgio
- Lampasona, Vito
- Ciceri, Fabio
- Barreiros, Lucil ...
- Dominguez-Garrid ...
- Vidigal, Mateus
- Zatz, Mayana
- van de Beek, Die ...
- Sahanic, Sabina
- Tancevski, Ivan
- Stepanovskyy, Yu ...
- Boyarchuk, Oksan ...
- Nukui, Yoko
- Tsumura, Miyuki
- Vidaur, Loreto
- Tangye, Stuart G
- Burrel, Sonia
- Duffy, Darragh
- Quintana-Murci, ...
- Klocperk, Adam
- Kann, Nelli Y
- Shcherbina, Anna
- Lau, Yu-Lung
- Leung, Daniel
- Coulongeat, Matt ...
- Marlet, Julien
- Koning, Rutger
- Reyes, Luis Feli ...
- Chauvineau-Greni ...
- Venet, Fabienne
- Monneret, Guilla ...
- Nussenzweig, Mic ...
- Arrestier, Romai ...
- Boudhabhay, Idri ...
- Baris-Feldman, H ...
- Hagin, David
- Wauters, Joost
- Meyts, Isabelle
- Dyer, Adam H
- Kennelly, Sean P
- Bourke, Nollaig ...
- Halwani, Rabih
- Sharif-Askari, F ...
- Dorgham, Karim
- Sallette, Jérôme
- Sedkaoui, Souad ...
- AlKhater, Suzan
- Rigo-Bonnin, Raú ...
- Morandeira, Fran ...
- Roussel, Lucie
- Vinh, Donald C
- Erikstrup, Chris ...
- Condino-Neto, An ...
- Prando, Carolina
- Bondarenko, Anas ...
- Spaan, András N
- Gilardin, Lauren ...
- Fellay, Jacques
- Lyonnet, Stanisl ...
- Bilguvar, Kaya
- Lifton, Richard ...
- Mane, Shrikant
- Ekwall, Olov, 19 ...
- Anderson, Mark S
- Boisson, Bertran ...
- Béziat, Vivien
- Zhang, Shen-Ying
- Andreakos, Evang ...
- Hermine, Olivier
- Pujol, Aurora
- Peterson, Pärt
- Mogensen, Trine ...
- Rowen, Lee
- Mond, James
- Debette, Stéphan ...
- de Lamballerie, ...
- Burdet, Charles
- Bouadma, Lila
- Zins, Marie
- Soler-Palacin, P ...
- Colobran, Roger
- Gorochov, Guy
- Solanich, Xavier
- Susen, Sophie
- Martinez-Picado, ...
- Raoult, Didier
- Vasse, Marc
- Gregersen, Peter ...
- Piemonti, Lorenz ...
- Rodríguez-Galleg ...
- Notarangelo, Lui ...
- Su, Helen C
- Kisand, Kai
- Okada, Satoshi
- Puel, Anne
- Jouanguy, Emmanu ...
- Rice, Charles M
- Tiberghien, Pier ...
- Zhang, Qian
- Casanova, Jean-L ...
- Abel, Laurent
- Cobat, Aurélie
- visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Pediatrik
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Reumatologi och ...
- Artiklar i publikationen
- Proceedings of t ...
- Proceedings of t ...
- Av lärosätet
- Göteborgs universitet
- Karolinska Institutet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
