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Sökning: WFRF:(Newton Bishop J) > (2006-2009) > A pooled analysis o...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004584naa a2200685 4500
001oai:lup.lub.lu.se:4a1a5ae2-9b08-4ed4-81f3-6f2b2eafd6a3
003SwePub
008160401s2009 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/13136052 URI
0247 a https://doi.org/10.1002/ijc.238692 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Chang, Yu-mei4 aut
2451 0a A pooled analysis of Melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes
264 1b Wiley,c 2009
520 a An abnormal nevus phenotype is associated with an increased risk of melanoma. We report a pooled analysis conducted using individual nevus data from 15 case-control studies (5,421 melanoma cases and 6,966 controls). The aims were to quantify the risk better and to determine whether relative risk is varied by latitude. Bayesian unconditional logistic random coefficients models were employed to study the risk associated with nevus characteristics. Participants with whole body nevus counts in the highest of 4 population-based categories had a greatly increased risk of melanoma compared with those in the lowest category (pooled odds ratio (pOR) 6.9 (95% confidence interval (CI): 4.4, 1.1.2) for those aged <50 years and pOR 5.1 (95% CI: 3.6, 7.5) for those aged >= 50). The pOR for presence compared with absence of any clinically atypical nevi was 4.0 (95 % CI: 2.8, 5.8). The pORs for 1-2 and >= 3 large nevi on the body compared with none were 2.9 (95% CI: 1.9, 4.3) and 7.1 (95% CI: 4.7, 11.6), respectively. The relative heterogeneities among studies were small for most measures of nevus phenotype, except for the analysis of nevus counts on the arms, which may have been due to methodological differences among studies. The pooled analysis also suggested that an abnormal nevus phenotype is associated most with melanomas on intermittently sun-exposed sites. The presence of increased numbers of nevi, large nevi and clinically atypical nevi on the body are robust risk factors for melanoma showing little variation in relative risk among studies performed at different latitudes. (C) 2008 Wiley-Liss, Inc.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a Bayesian
653 a pooled analysis
653 a latitude
653 a melanoma
653 a nevus
7001 a Newton-Bishop, Julia A.4 aut
7001 a Bishop, D. Timothy4 aut
7001 a Armstrong, Bruce K.4 aut
7001 a Bataille, Veronique4 aut
7001 a Bergman, Wilma4 aut
7001 a Berwick, Marianne4 aut
7001 a Bracci, Paige M.4 aut
7001 a Elwood, J. Mark4 aut
7001 a Ernstoff, Marc S.4 aut
7001 a Green, Adele C.4 aut
7001 a Gruis, Nelleke A.4 aut
7001 a Holly, Elizabeth A.4 aut
7001 a Ingvar, Christianu Lund University,Lunds universitet,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)kir-cin
7001 a Kanetsky, Peter A.4 aut
7001 a Karagas, Margaret R.4 aut
7001 a Le Marchand, Loic4 aut
7001 a Mackie, Rona M.4 aut
7001 a Olsson, Håkanu Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)onk-hol
7001 a Osterlind, Anne4 aut
7001 a Rebbeck, Timothy R.4 aut
7001 a Reich, Kristian4 aut
7001 a Sasieni, Peter4 aut
7001 a Siskind, Victor4 aut
7001 a Swerdlow, Anthony I.4 aut
7001 a Titus-Ernstoff, Linda4 aut
7001 a Zens, Michael S.4 aut
7001 a Ziegler, Andreas4 aut
7001 a Barrett, Jennifer H.4 aut
7102 a Kirurgi, Lundb Sektion V4 org
7730 t International Journal of Cancerd : Wileyg 124:2, s. 420-428q 124:2<420-428x 0020-7136x 1097-0215
8564 u http://dx.doi.org/10.1002/ijc.23869y FULLTEXT
8564 u https://www.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.23869
8564 8u https://lup.lub.lu.se/record/1313605
8564 8u https://doi.org/10.1002/ijc.23869

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