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Increased occurrence of hepatitis A with cyclic outbreaks among drug addicts in a Swedish community

Widell, Anders (author)
Lund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups
Hansson, Bengt-Göran (author)
Lund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups
Moestrup, T (author)
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Nordenfelt, E (author)
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 (creator_code:org_t)
1983
1983
English.
In: Infection. - 1439-0973. ; 11:4, s. 198-200
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • To determine the prevalence of antibodies to Hepatitis A virus (anti-HAV) among drug addicts, sera collected in a Swedish city during a ten-year period from 234 drug addicts with acute hepatitis B were tested for anti-HAV. The results were compared with the normal population, where only 3.8% of those born after 1950 were anti-HAV-positive. In individuals born between 1941 and 1965, 8.2% in the normal population and 30.2% of the drug addicts were anti-HAV-positive (p less than 0.001). The level of immunity to hepatitis A among drug addicts ranged from 7.7% to 60% during the ten-year period. Low levels of immunity were seen in the years preceeding outbreaks of hepatitis A among drug addicts. These outbreaks occurred in a cyclic pattern. Higher levels of immunity were seen after each outbreak.
  • Abstract in German Zur Bestimmung der Prävalenz vonHepatitis A Virus-Antikörpern (anti-HAV) bei Drogenabhängigen wurden Seren von 234 Drogenabhängigen mit akuter Hepatitis B, die in einer schwedischen Stadt während zehn Jahren gesammelt worden waren, auf anti-HAV getestet. Zum Vergleich wurde eine normale Bevölkerungsgruppe herangezogen, bei der nur 3,8% der nach 1950 Geborenen und 8,2% der Jahrgänge 1941–1965 anti-HAV positiv waren. Hingegen war bei 30,2% der Drogenabhängigen anti-HAV nachzuweisen (p<0,001). Die Rate von Drogenabhängigen mit Immunschutz variierte innerhalb von zehn Jahren zwischen 7,7% und 60%. In den Jahren von Hepatitis A-Ausbrüchen waren die Immunitätsraten jeweils niedrig. Die Ausbrüche traten zyklisch auf. Nach jedem Ausbruch war jeweils eine höhere Rate von Drogensüchtigen mit Immunschutz festzustellen.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Microbiology in the medical area (hsv//eng)

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Widell, Anders
Hansson, Bengt-G ...
Moestrup, T
Nordenfelt, E
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MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Basic Medicine
and Microbiology in ...
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Infection
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Lund University

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