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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 08778naa a2202389 4500 | |
| 001 | oai:DiVA.org:uu-223021 | |
| 003 | SwePub | |
| 008 | 140416s2010 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:121622680 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2230212 URI |
| 024 | 7 | a https://doi.org/10.1038/ng.7142 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1216226802 URI |
| 040 | a (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Elks, Cathy E4 aut |
| 245 | 1 0 | a Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies |
| 264 | c 2010-11-21 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2010 |
| 338 | a print2 rdacarrier | |
| 520 | a To identify loci for age at menarche, we performed a meta-analysis of 32 genome-wide association studies in 87,802 women of European descent, with replication in up to 14,731 women. In addition to the known loci at LIN28B (P = 5.4 × 10⁻⁶⁰) and 9q31.2 (P = 2.2 × 10⁻³³), we identified 30 new menarche loci (all P < 5 × 10⁻⁸) and found suggestive evidence for a further 10 loci (P < 1.9 × 10⁻⁶). The new loci included four previously associated with body mass index (in or near FTO, SEC16B, TRA2B and TMEM18), three in or near other genes implicated in energy homeostasis (BSX, CRTC1 and MCHR2) and three in or near genes implicated in hormonal regulation (INHBA, PCSK2 and RXRG). Ingenuity and gene-set enrichment pathway analyses identified coenzyme A and fatty acid biosynthesis as biological processes related to menarche timing. | |
| 700 | 1 | a Perry, John R B4 aut |
| 700 | 1 | a Sulem, Patrick4 aut |
| 700 | 1 | a Chasman, Daniel I4 aut |
| 700 | 1 | a Franceschini, Nora4 aut |
| 700 | 1 | a He, Chunyan4 aut |
| 700 | 1 | a Lunetta, Kathryn L4 aut |
| 700 | 1 | a Visser, Jenny A4 aut |
| 700 | 1 | a Byrne, Enda M4 aut |
| 700 | 1 | a Cousminer, Diana L4 aut |
| 700 | 1 | a Gudbjartsson, Daniel F4 aut |
| 700 | 1 | a Esko, Tõnu4 aut |
| 700 | 1 | a Feenstra, Bjarke4 aut |
| 700 | 1 | a Hottenga, Jouke-Jan4 aut |
| 700 | 1 | a Koller, Daniel L4 aut |
| 700 | 1 | a Kutalik, Zoltán4 aut |
| 700 | 1 | a Lin, Peng4 aut |
| 700 | 1 | a Mangino, Massimo4 aut |
| 700 | 1 | a Marongiu, Mara4 aut |
| 700 | 1 | a McArdle, Patrick F4 aut |
| 700 | 1 | a Smith, Albert V4 aut |
| 700 | 1 | a Stolk, Lisette4 aut |
| 700 | 1 | a van Wingerden, Sophie H4 aut |
| 700 | 1 | a Zhao, Jing Hua4 aut |
| 700 | 1 | a Albrecht, Eva4 aut |
| 700 | 1 | a Corre, Tanguy4 aut |
| 700 | 1 | a Ingelsson, Erik,d 1975-u Karolinska Institutet4 aut0 (Swepub:uu)ering425 |
| 700 | 1 | a Hayward, Caroline4 aut |
| 700 | 1 | a Magnusson, Patrik K Eu Karolinska Institutet4 aut |
| 700 | 1 | a Smith, Erin N4 aut |
| 700 | 1 | a Ulivi, Shelia4 aut |
| 700 | 1 | a Warrington, Nicole M4 aut |
| 700 | 1 | a Zgaga, Lina4 aut |
| 700 | 1 | a Alavere, Helen4 aut |
| 700 | 1 | a Amin, Najaf4 aut |
| 700 | 1 | a Aspelund, Thor4 aut |
| 700 | 1 | a Bandinelli, Stefania4 aut |
| 700 | 1 | a Barroso, Inês4 aut |
| 700 | 1 | a Berenson, Gerald S4 aut |
| 700 | 1 | a Bergmann, Sven4 aut |
| 700 | 1 | a Blackburn, Hannah4 aut |
| 700 | 1 | a Boerwinkle, Eric4 aut |
| 700 | 1 | a Buring, Julie E4 aut |
| 700 | 1 | a Busonero, Fabio4 aut |
| 700 | 1 | a Campbell, Harry4 aut |
| 700 | 1 | a Chanock, Stephen J4 aut |
| 700 | 1 | a Chen, Wei4 aut |
| 700 | 1 | a Cornelis, Marilyn C4 aut |
| 700 | 1 | a Couper, David4 aut |
| 700 | 1 | a Coviello, Andrea D4 aut |
| 700 | 1 | a d'Adamo, Pio4 aut |
| 700 | 1 | a de Faire, Ulfu Karolinska Institutet4 aut |
| 700 | 1 | a de Geus, Eco J C4 aut |
| 700 | 1 | a Deloukas, Panos4 aut |
| 700 | 1 | a Döring, Angela4 aut |
| 700 | 1 | a Smith, George Davey4 aut |
| 700 | 1 | a Easton, Douglas F4 aut |
| 700 | 1 | a Eiriksdottir, Gudny4 aut |
| 700 | 1 | a Emilsson, Valur4 aut |
| 700 | 1 | a Eriksson, Johan4 aut |
| 700 | 1 | a Ferrucci, Luigi4 aut |
| 700 | 1 | a Folsom, Aaron R4 aut |
| 700 | 1 | a Foroud, Tatiana4 aut |
| 700 | 1 | a Garcia, Melissa4 aut |
| 700 | 1 | a Gasparini, Paolo4 aut |
| 700 | 1 | a Geller, Frank4 aut |
| 700 | 1 | a Gieger, Christian4 aut |
| 700 | 1 | a Gudnason, Vilmundur4 aut |
| 700 | 1 | a Hall, Peru Karolinska Institutet4 aut |
| 700 | 1 | a Hankinson, Susan E4 aut |
| 700 | 1 | a Ferreli, Liana4 aut |
| 700 | 1 | a Heath, Andrew C4 aut |
| 700 | 1 | a Hernandez, Dena G4 aut |
| 700 | 1 | a Hofman, Albert4 aut |
| 700 | 1 | a Hu, Frank B4 aut |
| 700 | 1 | a Illig, Thomas4 aut |
| 700 | 1 | a Järvelin, Marjo-Riitta4 aut |
| 700 | 1 | a Johnson, Andrew D4 aut |
| 700 | 1 | a Karasik, David4 aut |
| 700 | 1 | a Khaw, Kay-Tee4 aut |
| 700 | 1 | a Kiel, Douglas P4 aut |
| 700 | 1 | a Kilpeläinen, Tuomas O4 aut |
| 700 | 1 | a Kolcic, Ivana4 aut |
| 700 | 1 | a Kraft, Peter4 aut |
| 700 | 1 | a Launer, Lenore J4 aut |
| 700 | 1 | a Laven, Joop S E4 aut |
| 700 | 1 | a Li, Shengxu4 aut |
| 700 | 1 | a Liu, Jianjun4 aut |
| 700 | 1 | a Levy, Daniel4 aut |
| 700 | 1 | a Martin, Nicholas G4 aut |
| 700 | 1 | a McArdle, Wendy L4 aut |
| 700 | 1 | a Melbye, Mads4 aut |
| 700 | 1 | a Mooser, Vincent4 aut |
| 700 | 1 | a Murray, Jeffrey C4 aut |
| 700 | 1 | a Murray, Sarah S4 aut |
| 700 | 1 | a Nalls, Michael A4 aut |
| 700 | 1 | a Navarro, Pau4 aut |
| 700 | 1 | a Nelis, Mari4 aut |
| 700 | 1 | a Ness, Andrew R4 aut |
| 700 | 1 | a Northstone, Kate4 aut |
| 700 | 1 | a Oostra, Ben A4 aut |
| 700 | 1 | a Peacock, Munro4 aut |
| 700 | 1 | a Palmer, Lyle J4 aut |
| 700 | 1 | a Palotie, Aarno4 aut |
| 700 | 1 | a Paré, Guillaume4 aut |
| 700 | 1 | a Parker, Alex N4 aut |
| 700 | 1 | a Pedersen, Nancy Lu Karolinska Institutet4 aut |
| 700 | 1 | a Peltonen, Leena4 aut |
| 700 | 1 | a Pennell, Craig E4 aut |
| 700 | 1 | a Pharoah, Paul4 aut |
| 700 | 1 | a Polasek, Ozren4 aut |
| 700 | 1 | a Plump, Andrew S4 aut |
| 700 | 1 | a Pouta, Anneli4 aut |
| 700 | 1 | a Porcu, Eleonora4 aut |
| 700 | 1 | a Rafnar, Thorunn4 aut |
| 700 | 1 | a Rice, John P4 aut |
| 700 | 1 | a Ring, Susan M4 aut |
| 700 | 1 | a Rivadeneira, Fernando4 aut |
| 700 | 1 | a Rudan, Igor4 aut |
| 700 | 1 | a Sala, Cinzia4 aut |
| 700 | 1 | a Salomaa, Veikko4 aut |
| 700 | 1 | a Sanna, Serena4 aut |
| 700 | 1 | a Schlessinger, David4 aut |
| 700 | 1 | a Schork, Nicholas J4 aut |
| 700 | 1 | a Scuteri, Angelo4 aut |
| 700 | 1 | a Segrè, Ayellet V4 aut |
| 700 | 1 | a Shuldiner, Alan R4 aut |
| 700 | 1 | a Soranzo, Nicole4 aut |
| 700 | 1 | a Sovio, Ulla4 aut |
| 700 | 1 | a Srinivasan, Sathanur R4 aut |
| 700 | 1 | a Strachan, David P4 aut |
| 700 | 1 | a Tammesoo, Mar-Liis4 aut |
| 700 | 1 | a Tikkanen, Emmi4 aut |
| 700 | 1 | a Toniolo, Daniela4 aut |
| 700 | 1 | a Tsui, Kim4 aut |
| 700 | 1 | a Tryggvadottir, Laufey4 aut |
| 700 | 1 | a Tyrer, Jonathon4 aut |
| 700 | 1 | a Uda, Manuela4 aut |
| 700 | 1 | a van Dam, Rob M4 aut |
| 700 | 1 | a van Meurs, Joyce B J4 aut |
| 700 | 1 | a Vollenweider, Peter4 aut |
| 700 | 1 | a Waeber, Gerard4 aut |
| 700 | 1 | a Wareham, Nicholas J4 aut |
| 700 | 1 | a Waterworth, Dawn M4 aut |
| 700 | 1 | a Weedon, Michael N4 aut |
| 700 | 1 | a Wichmann, H Erich4 aut |
| 700 | 1 | a Willemsen, Gonneke4 aut |
| 700 | 1 | a Wilson, James F4 aut |
| 700 | 1 | a Wright, Alan F4 aut |
| 700 | 1 | a Young, Lauren4 aut |
| 700 | 1 | a Zhai, Guangju4 aut |
| 700 | 1 | a Zhuang, Wei Vivian4 aut |
| 700 | 1 | a Bierut, Laura J4 aut |
| 700 | 1 | a Boomsma, Dorret I4 aut |
| 700 | 1 | a Boyd, Heather A4 aut |
| 700 | 1 | a Crisponi, Laura4 aut |
| 700 | 1 | a Demerath, Ellen W4 aut |
| 700 | 1 | a van Duijn, Cornelia M4 aut |
| 700 | 1 | a Econs, Michael J4 aut |
| 700 | 1 | a Harris, Tamara B4 aut |
| 700 | 1 | a Hunter, David J4 aut |
| 700 | 1 | a Loos, Ruth J F4 aut |
| 700 | 1 | a Metspalu, Andres4 aut |
| 700 | 1 | a Montgomery, Grant W4 aut |
| 700 | 1 | a Ridker, Paul M4 aut |
| 700 | 1 | a Spector, Tim D4 aut |
| 700 | 1 | a Streeten, Elizabeth A4 aut |
| 700 | 1 | a Stefansson, Kari4 aut |
| 700 | 1 | a Thorsteinsdottir, Unnur4 aut |
| 700 | 1 | a Uitterlinden, André G4 aut |
| 700 | 1 | a Widen, Elisabeth4 aut |
| 700 | 1 | a Murabito, Joanne M4 aut |
| 700 | 1 | a Ong, Ken K4 aut |
| 700 | 1 | a Murray, Anna4 aut |
| 710 | 2 | a Karolinska Institutet4 org |
| 773 | 0 | t Nature Geneticsd : Springer Science and Business Media LLCg 42:12, s. 1077-85q 42:12<1077-85x 1061-4036x 1546-1718 |
| 856 | 4 | u https://europepmc.org/articles/pmc3140055?pdf=render |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-223021 |
| 856 | 4 8 | u https://doi.org/10.1038/ng.714 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:121622680 |
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- Elks, Cathy E
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- Koller, Daniel L
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- Smith, Albert V
- Stolk, Lisette
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- Zhao, Jing Hua
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- Hayward, Carolin ...
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- Barroso, Inês
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- Bergmann, Sven
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- Boerwinkle, Eric
- Buring, Julie E
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- Couper, David
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- d'Adamo, Pio
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- Johnson, Andrew ...
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- Kilpeläinen, Tuo ...
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- Kraft, Peter
- Launer, Lenore J
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- Levy, Daniel
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- Parker, Alex N
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- Pharoah, Paul
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- Rice, John P
- Ring, Susan M
- Rivadeneira, Fer ...
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- Sala, Cinzia
- Salomaa, Veikko
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- Segrè, Ayellet V
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