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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005283naa a2200901 4500
001oai:gup.ub.gu.se/299505
003SwePub
008240528s2021 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:145755281
0247 a https://gup.ub.gu.se/publication/2995052 URI
0247 a https://doi.org/10.1530/EJE-20-11802 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1457552812 URI
040 a (SwePub)gud (SwePub)ki
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Martel-Duguech, Luciana Maria4 aut
2451 0a ESE audit on management of Adult Growth Hormone Deficiency in clinical practice.
264 1c 2021
520 a Guidelines recommend adults with pituitary disease in whom GH therapy is contemplated, to be tested for GH deficiency (AGHD); however, clinical practice is not uniform.1) To record current practice of AGHD management throughout Europe and benchmark it against guidelines; 2) To evaluate educational status of healthcare professionals about AGHD.On-line survey in endocrine centres throughout Europe.Endocrinologists voluntarily completed an electronic questionnaire regarding AGHD patients diagnosed or treated in 2017-2018.Twenty-eight centres from 17 European countries participated, including 2139 AGHD patients, 28% of childhood-onset GHD. Aetiology was most frequently non-functioning pituitary adenoma (26%), craniopharyngioma (13%) and genetic/congenital mid-line malformations (13%). Diagnosis of GHD was confirmed by a stimulation test in 52% (GHRH+arginine, 45%; insulin-tolerance, 42%, glucagon, 6%; GHRH alone and clonidine tests, 7%); in the remaining, ≥3 pituitary deficiencies and low serum IGF-I were diagnostic. Initial GH dose was lower in older patients, but only women <26 years were prescribed a higher dose than men; dose titration was based on normal serum IGF-I, tolerance and side-effects. In one country, AGHD treatment was not approved. Full public reimbursement was not available in four countries and only in childhood-onset GHD in another. AGHD awareness was low among non-endocrine professionals and healthcare administrators. Postgraduate AGHD curriculum training deserves being improved.Despite guideline recommendations, GH replacement in AGHD is still not available or reimbursed in all European countries. Knowledge among professionals and health administrators needs improvement to optimize care of adults with GHD.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
7001 a Jorgensen, Jens Otto L4 aut
7001 a Korbonits, Marta4 aut
7001 a Johannsson, Gudmundur,d 1960u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition4 aut0 (Swepub:gu)xjgudn
7001 a Webb, Susan M4 aut
7001 a Amadidou, Fotini4 aut
7001 a Mintziori, G4 aut
7001 a Arosio, Maura4 aut
7001 a Giavoli, Claudia4 aut
7001 a Badiu, Corin4 aut
7001 a Boschetti, Mara4 aut
7001 a Ferone, Diego4 aut
7001 a Ricci Bitti, Silvia4 aut
7001 a Brue, Thierry4 aut
7001 a Albarel, F4 aut
7001 a Cannavò, Salvatore4 aut
7001 a Cotta, Oana Ruxandra4 aut
7001 a Carvalho, Davide4 aut
7001 a Salazar, Daniela4 aut
7001 a Christ, Emanuel4 aut
7001 a Debono, Miguel4 aut
7001 a Dusek, Tina4 aut
7001 a Garcia-Centeno, Rogelio4 aut
7001 a Ghigo, Ezio4 aut
7001 a Gasco, Valentina4 aut
7001 a Góth, Miklós I4 aut
7001 a Oláh, Dóra4 aut
7001 a Kovacs, Laszlo4 aut
7001 a Höybye, Charlotte4 aut
7001 a Kocjan, Tomaz4 aut
7001 a Mlekuš Kozamernik, Katarina4 aut
7001 a Kužma, Martin4 aut
7001 a Payer, Juraj4 aut
7001 a Medic-Stojanoska, Milica4 aut
7001 a Novak, Anela4 aut
7001 a Miličević, Tanja4 aut
7001 a Pekic, Sandra4 aut
7001 a Miljic, Dragana4 aut
7001 a Perez Luis, Jesus4 aut
7001 a Pico, Antonio M4 aut
7001 a Preda, Veronica4 aut
7001 a Raverot, Gerald4 aut
7001 a Borson-Chazot, Francoise4 aut
7001 a Rochira, Vincenzo4 aut
7001 a Monzani, María Laura4 aut
7001 a Sandahl, Kristian4 aut
7001 a Tsagarakis, Stylianos4 aut
7001 a Mitravela, Vana4 aut
7001 a Zacharieva, Sabina4 aut
7001 a Zilaitiene, Birute4 aut
7001 a Verkauskiene, Rasa4 aut
7102 a Göteborgs universitetb Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition4 org
7730 t European journal of endocrinologyg 184:2, s. 323-334q 184:2<323-334x 1479-683X
8564 8u https://gup.ub.gu.se/publication/299505
8564 8u https://doi.org/10.1530/EJE-20-1180
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:145755281

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