Search: WFRF:(Carver Jeremy) > (2007-2009) > Comparative genomic...
Fältnamn | Indikatorer | Metadata |
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000 | 04374naa a2200985 4500 | |
001 | oai:DiVA.org:uu-15051 | |
003 | SwePub | |
008 | 080204s2007 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-150512 URI |
024 | 7 | a https://doi.org/10.1038/ng20532 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Peacock, Christopher S4 aut |
245 | 1 0 | a Comparative genomic analysis of three Leishmania species that cause diverse human disease. |
264 | c 2007-06-17 | |
264 | 1 | b Springer Science and Business Media LLC,c 2007 |
338 | a print2 rdacarrier | |
520 | a Leishmania parasites cause a broad spectrum of clinical disease. Here we report the sequencing of the genomes of two species of Leishmania: Leishmania infantum and Leishmania braziliensis. The comparison of these sequences with the published genome of Leishmania major reveals marked conservation of synteny and identifies only 200 genes with a differential distribution between the three species. L. braziliensis, contrary to Leishmania species examined so far, possesses components of a putative RNA-mediated interference pathway, telomere-associated transposable elements and spliced leader–associated SLACS retrotransposons. We show that pseudogene formation and gene loss are the principal forces shaping the different genomes. Genes that are differentially distributed between the species encode proteins implicated in host-pathogen interactions and parasite survival in the macrophage. | |
650 | 7 | a NATURVETENSKAPx Biologi0 (SwePub)1062 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciences0 (SwePub)1062 hsv//eng |
653 | a Amino Acid Sequence | |
653 | a Animals | |
653 | a Genome | |
653 | a Genomics | |
653 | a Humans | |
653 | a Leishmania/*genetics | |
653 | a Leishmania braziliensis/genetics | |
653 | a Leishmania infantum/genetics | |
653 | a Leishmania major/genetics | |
653 | a Leishmaniasis/*parasitology | |
653 | a Leishmaniasis; Cutaneous/parasitology | |
653 | a Leishmaniasis; Visceral/parasitology | |
653 | a Molecular Sequence Data | |
653 | a Biology | |
653 | a Biologi | |
700 | 1 | a Seeger, Kathy4 aut |
700 | 1 | a Harris, David4 aut |
700 | 1 | a Murphy, Lee4 aut |
700 | 1 | a Ruiz, Jeronimo C4 aut |
700 | 1 | a Quail, Michael A4 aut |
700 | 1 | a Peters, Nick4 aut |
700 | 1 | a Adlem, Ellen4 aut |
700 | 1 | a Tivey, Adrian4 aut |
700 | 1 | a Aslett, Martin4 aut |
700 | 1 | a Kerhornou, Arnaud4 aut |
700 | 1 | a Ivens, Alasdair4 aut |
700 | 1 | a Fraser, Audrey4 aut |
700 | 1 | a Rajandream, Marie-Adele4 aut |
700 | 1 | a Carver, Tim4 aut |
700 | 1 | a Norbertczak, Halina4 aut |
700 | 1 | a Chillingworth, Tracey4 aut |
700 | 1 | a Hance, Zahra4 aut |
700 | 1 | a Jagels, Kay4 aut |
700 | 1 | a Moule, Sharon4 aut |
700 | 1 | a Ormond, Doug4 aut |
700 | 1 | a Rutter, Simon4 aut |
700 | 1 | a Squares, Rob4 aut |
700 | 1 | a Whitehead, Sally4 aut |
700 | 1 | a Rabbinowitsch, Ester4 aut |
700 | 1 | a Arrowsmith, Claire4 aut |
700 | 1 | a White, Brian4 aut |
700 | 1 | a Thurston, Scott4 aut |
700 | 1 | a Bringaud, Frédéric4 aut |
700 | 1 | a Baldauf, Sandra Lu Uppsala universitet,Systematisk botanik4 aut0 (Swepub:uu)sanba878 |
700 | 1 | a Faulconbridge, Adam4 aut |
700 | 1 | a Jeffares, Daniel4 aut |
700 | 1 | a Depledge, Daniel P4 aut |
700 | 1 | a Oyola, Samuel O4 aut |
700 | 1 | a Hilley, James D4 aut |
700 | 1 | a Brito, Loislene O4 aut |
700 | 1 | a Tosi, Luiz R O4 aut |
700 | 1 | a Barrell, Barclay4 aut |
700 | 1 | a Cruz, Angela K4 aut |
700 | 1 | a Mottram, Jeremy C4 aut |
700 | 1 | a Smith, Deborah F4 aut |
700 | 1 | a Berriman, Matthew4 aut |
710 | 2 | a Uppsala universitetb Systematisk botanik4 org |
773 | 0 | t Nature Geneticsd : Springer Science and Business Media LLCg 39:7, s. 839-847q 39:7<839-847x 1061-4036x 1546-1718 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=17572675&dopt=Citation |
856 | 4 | u https://europepmc.org/articles/pmc2592530?pdf=render |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-15051 |
856 | 4 8 | u https://doi.org/10.1038/ng2053 |
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