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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 20677naa a2201837 4500 | |
| 001 | oai:DiVA.org:umu-191149 | |
| 003 | SwePub | |
| 008 | 220110s2021 | |||||||||||000 ||eng| | |
| 009 | oai:gup.ub.gu.se/310518 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1911492 URI |
| 024 | 7 | a https://doi.org/10.1001/jamaneurol.2021.36192 DOI |
| 024 | 7 | a https://gup.ub.gu.se/publication/3105182 URI |
| 040 | a (SwePub)umud (SwePub)gu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Sánchez Van Kammen, Mayteu Department of Neurology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 245 | 1 0 | a Characteristics and Outcomes of Patients with Cerebral Venous Sinus Thrombosis in SARS-CoV-2 Vaccine-Induced Immune Thrombotic Thrombocytopenia |
| 264 | 1 | b American Medical Association,c 2021 |
| 338 | a print2 rdacarrier | |
| 520 | a Importance: Thrombosis with thrombocytopenia syndrome (TTS) has been reported after vaccination with the SARS-CoV-2 vaccines ChAdOx1 nCov-19 (Oxford-AstraZeneca) and Ad26.COV2.S (Janssen/Johnson & Johnson).Objective: To describe the clinical characteristics and outcome of patients with cerebral venous sinus thrombosis (CVST) after SARS-CoV-2 vaccination with and without TTS.Design, Setting, and Participants: This cohort study used data from an international registry of consecutive patients with CVST within 28 days of SARS-CoV-2 vaccination included between March 29 and June 18, 2021, from 81 hospitals in 19 countries. For reference, data from patients with CVST between 2015 and 2018 were derived from an existing international registry. Clinical characteristics and mortality rate were described for adults with (1) CVST in the setting of SARS-CoV-2 vaccine-induced immune thrombotic thrombocytopenia, (2) CVST after SARS-CoV-2 vaccination not fulling criteria for TTS, and (3) CVST unrelated to SARS-CoV-2 vaccination.Exposures: Patients were classified as having TTS if they had new-onset thrombocytopenia without recent exposure to heparin, in accordance with the Brighton Collaboration interim criteria.Main Outcomes and Measures: Clinical characteristics and mortality rate.Results: Of 116 patients with postvaccination CVST, 78 (67.2%) had TTS, of whom 76 had been vaccinated with ChAdOx1 nCov-19; 38 (32.8%) had no indication of TTS. The control group included 207 patients with CVST before the COVID-19 pandemic. A total of 63 of 78 (81%), 30 of 38 (79%), and 145 of 207 (70.0%) patients, respectively, were female, and the mean (SD) age was 45 (14), 55 (20), and 42 (16) years, respectively. Concomitant thromboembolism occurred in 25 of 70 patients (36%) in the TTS group, 2 of 35 (6%) in the no TTS group, and 10 of 206 (4.9%) in the control group, and in-hospital mortality rates were 47% (36 of 76; 95% CI, 37-58), 5% (2 of 37; 95% CI, 1-18), and 3.9% (8 of 207; 95% CI, 2.0-7.4), respectively. The mortality rate was 61% (14 of 23) among patients in the TTS group diagnosed before the condition garnered attention in the scientific community and 42% (22 of 53) among patients diagnosed later.Conclusions and Relevance: In this cohort study of patients with CVST, a distinct clinical profile and high mortality rate was observed in patients meeting criteria for TTS after SARS-CoV-2 vaccination.. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
| 653 | a diagnosis | |
| 653 | a Neurosciences & Neurology | |
| 700 | 1 | a Aguiar De Sousa, Dianau Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte, University of Lisbon, Lisbon, Portugal4 aut |
| 700 | 1 | a Poli, Svenu Department of Neurology and Stroke, Eberhard-Karls University, Tuebingen, Germany; Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tuebingen, Germany4 aut |
| 700 | 1 | a Cordonnier, Charlotteu Department of Neurosciences and Cognition, Lille University Hospital, Lille, France4 aut |
| 700 | 1 | a Heldner, Mirjam R.u Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland4 aut |
| 700 | 1 | a Van De Munckhof, Anitau Department of Neurology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a Krzywicka, Katarzynau Department of Neurology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a Van Haaps, Thijsu Department of Internal Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a Ciccone, Alfonsou Department of Neurology, Carlo Poma Hospital, Azienda Socio Sanitaria Territoriale di Mantova, Mantua, Italy4 aut |
| 700 | 1 | a Middeldorp, Saskiau Department of Internal Medicine, Radboud Institute of Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands4 aut |
| 700 | 1 | a Levi, Marcel M.u National Institute for Health Research, University College London Hospitals, Biomedical Research Centre, London, United Kingdom4 aut |
| 700 | 1 | a Kremer Hovinga, Johanna A.u Department of Hematology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland4 aut |
| 700 | 1 | a Silvis, Suzanneu Department of Neurology, Albert Schweitzer Hospital, Dordrecht, Netherlands4 aut |
| 700 | 1 | a Hiltunen, Siniu Department of Neurology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Mansour, Maryamu Sina Hospital, Hamadan University of Medical Science, Hamadan, Iran4 aut |
| 700 | 1 | a Arauz, Antoniou National Institute of Neurology and Neurosurgery Manuel Velasco Suarez, Mexico City, Mexico4 aut |
| 700 | 1 | a Barboza, Miguel A.u Neurosciences Department, Hospital Dr R.A. Calderón Guardia, San José, Costa Rica4 aut |
| 700 | 1 | a Field, Thalia S.u Division of Neurology, University of British Columbia, Vancouver Stroke Program, BC, Vancouver, Canada4 aut |
| 700 | 1 | a Tsivgoulis, Georgiosu Second Department of Neurology in National, Kapodistrian University of Athens, School of Medicine, Athens, Greece4 aut |
| 700 | 1 | a Nagel, Simonu Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany4 aut |
| 700 | 1 | a Lindgren, Erik,d 1993u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience4 aut0 (Swepub:gu)xliere |
| 700 | 1 | a Tatlisumak, Turgutu Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience4 aut0 (Swepub:gu)xtatlt |
| 700 | 1 | a Jood, Katarina,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience4 aut0 (Swepub:gu)xjooka |
| 700 | 1 | a Putaala, Jukkau Department of Neurology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Ferro, Jose M.u Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte, University of Lisbon, Lisbon, Portugal4 aut |
| 700 | 1 | a Arnold, Marcelu Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland4 aut |
| 700 | 1 | a Coutinho, Jonathan M.u Department of Neurology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands4 aut |
| 700 | 1 | a Sharma, Aarti R.u Imperial College London School of Medicine, Imperial College London, London, United Kingdom4 aut |
| 700 | 1 | a Elkady, Ahmedu Department of Neurology, Saudi German Hospital, Jeddah, Saudi Arabia4 aut |
| 700 | 1 | a Negro, Albertou Department of Neuroradiology, Ospedale Del Mare, Naples, Italy4 aut |
| 700 | 1 | a Günther, Albrechtu Department of Neurology, Jena University Hospital, Jena, Germany4 aut |
| 700 | 1 | a Gutschalk, Alexanderu Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany4 aut |
| 700 | 1 | a Schönenberger, Silviau Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany4 aut |
| 700 | 1 | a Buture, Alinau Acute Stroke Service, Mater Misericordiae University Hospital, Dublin, Ireland4 aut |
| 700 | 1 | a Murphy, Seanu Acute Stroke Service, Mater Misericordiae University Hospital, Dublin, Ireland; UCD School of Medicine, University College Dublin, Dublin, Ireland; School of Medicine, University of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland4 aut |
| 700 | 1 | a Paiva Nunes, Anau Department of Neurology, Centro Hospitalar de Lisboa Central, Lisbon, Portugal4 aut |
| 700 | 1 | a Tiede, Andreasu Clinic for Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany4 aut |
| 700 | 1 | a Puthuppallil Philip, Anemonu Department of Neurology, Hamilton General Hospital, ON, Hamilton, Canada4 aut |
| 700 | 1 | a Mengel, Anneroseu Department of Neurology and Stroke, University Hospital Tuebingen, Tuebingen, Germany4 aut |
| 700 | 1 | a Medina, Antoniou Department of Neurology, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain4 aut |
| 700 | 1 | a Hellström Vogel, Åslögu Department of Internal Medicine, Skåne University Hospital, Lund, Sweden4 aut |
| 700 | 1 | a Tawa, Audreyu Department of Anesthesia and Intensive Care, University Hospital of Rennes, Rennes, France4 aut |
| 700 | 1 | a Aujayeb, Avinashu Respiratory Department, Northumbria Healthcare NHS Foundation Trust, Cramlington, United Kingdom4 aut |
| 700 | 1 | a Casolla, Barbarau Respiratory Department, Northumbria Healthcare NHS Foundation Trust, Cramlington, United Kingdom; Stroke Unit, Hôpital Pasteur 2, URRIS - UR2CA, Unité de Recherche Clinique Cote d'Azur, Cote d'Azur University, Nice, France4 aut |
| 700 | 1 | a Buck, Brianu Division of Neurology, University of Alberta Hospital, AL, Edmonton, Canada4 aut |
| 700 | 1 | a Zanferrari, Carlau Department of Neurology, Azienda Ospedaliera di Melegnano e della Martesana, Melegnano, Italy4 aut |
| 700 | 1 | a Garcia-Esperon, Carlosu Department of Neurology, John Hunter Hospital, Newcastle, Australia4 aut |
| 700 | 1 | a Vayne, Carolineu Department of Hematology and Hemostasis, Tours University Hospital, Tours, France4 aut |
| 700 | 1 | a Legault, Catherineu Department of Neurology and Neurosurgery, McGill University Health Centre, QC, Montreal, Canada4 aut |
| 700 | 1 | a Pfrepper, Christianu Division of Hemostaseology, Leipzig University Hospital, Leipzig, Germany4 aut |
| 700 | 1 | a Tracol, Clementu Department of Neurology, CHU Rennes, Rennes, France4 aut |
| 700 | 1 | a Soriano, Cristinau Department of Neurology, Hospital General de Castellón, Castelló, Spain4 aut |
| 700 | 1 | a Guisado-Alonso, Danielu Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain4 aut |
| 700 | 1 | a Bougon, Davidu Department of Critical Care, Annecy Genevois Hospital, Annecy, France4 aut |
| 700 | 1 | a Zimatore, Domenico S.u Department of Neuroradiology, Policlinico di Bari, Bari, Italy4 aut |
| 700 | 1 | a Michalski, Dominiku Department of Neurology, Leipzig University Hospital, Leipzig, Germany4 aut |
| 700 | 1 | a Blacquiere, Dylanu Division of Neurology, Ottawa Hospital, ON, Ottawa, Canada4 aut |
| 700 | 1 | a Johansson, Eliasu Umeå universitet,Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM),Neurovetenskaper4 aut0 (Swepub:gu)xjeliw |
| 700 | 1 | a Cuadrado-Godia, Elisau Department of Neurology, University Hospital Del Mar, Barcelona, Spain4 aut |
| 700 | 1 | a De Maistre, Emmanuelu Department of Biological Haematology, CHU Dijon, Dijon, France4 aut |
| 700 | 1 | a Carrera, Emmanuelu Department of Neurology, Hôpitaux Universitaires de Genève, Geneva, Switzerland4 aut |
| 700 | 1 | a Vuillier, Fabriceu Stroke Unit, University Hospital of Besancon, Besancon, France4 aut |
| 700 | 1 | a Bonneville, Fabriceu Department of Neuroradiology, Toulouse University Hospital, Toulouse, France4 aut |
| 700 | 1 | a Giammello, Fabriziou Translational Molecular Medicine and Surgery, XXXV Cycle, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy4 aut |
| 700 | 1 | a Bode, Felix J.u Department of Neurology, Universitätsklinikum Bonn, Bonn, Germany4 aut |
| 700 | 1 | a Zimmerman, Julianu Department of Neurology, Universitätsklinikum Bonn, Bonn, Germany4 aut |
| 700 | 1 | a D'Onofrio, Florindou Department of Neurology, San Giuseppe Moscati Hospital, Avellino, Italy4 aut |
| 700 | 1 | a Grillo, Francescou Stroke Unit, Department of Clinical and Experimental Medicine, University Hospital G. Martino, Messina, Italy4 aut |
| 700 | 1 | a Cotton, Francoisu Department of Radiology, Lyon University Hospital, Lyon, France4 aut |
| 700 | 1 | a Caparros, Françoisu Department of Neurosciences and Cognition, Lille University Hospital, Lille, France4 aut |
| 700 | 1 | a Puy, Laurentu Department of Neurosciences and Cognition, Lille University Hospital, Lille, France4 aut |
| 700 | 1 | a Maier, Franku Department of Neurology, Caritas Hospital Saarbrücken, Saarbrücken, Germany4 aut |
| 700 | 1 | a Gulli, Giosueu Department of Medicine, Ashford and St Peters Hospital NHS Foundation Trust, Surrey, United Kingdom4 aut |
| 700 | 1 | a Frisullo, Giovanniu Department of Neurology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy4 aut |
| 700 | 1 | a Polkinghorne, Gregoryu Princess Alexandra Hospital, Brisbane, Australia4 aut |
| 700 | 1 | a Franchineau, Guillaumeu Department of Intensive Care, Centre Hospitalier Intercommunal de Poissy Saint Germain en Laye, Poissy, France4 aut |
| 700 | 1 | a Cangür, Hakanu Department of Neurology, Hospital of the City of Wolfsburg, Wolfsburg, Germany4 aut |
| 700 | 1 | a Katzberg, Hansu Department of Neuromuscular Medicine, Toronto General Hospital, ON, Toronto, Canada4 aut |
| 700 | 1 | a Sibon, Igoru Department of Neurology, Bordeaux University Hospital, Bordeaux, France4 aut |
| 700 | 1 | a Baharoglu, Iremu Department of Neurology, Haga Hospital, The Hague, Netherlands4 aut |
| 700 | 1 | a Brar, Jaskiranu Department of Neurology, Surrey Memorial Hospital, BC, Surrey, Canada4 aut |
| 700 | 1 | a Payen, Jean-Françoisu Department of Anesthesia and Critical Care, CHU Grenoble, Grenoble, France4 aut |
| 700 | 1 | a Burrow, Jimu Department of Neurology, Royal Darwin Hospital, Tiwi, Australia4 aut |
| 700 | 1 | a Fernandes, Joãou Department of Neurology, Norra Alvsborgs Länssjukhus, Trollhattan, Sweden4 aut |
| 700 | 1 | a Schouten, Judithu Department of Neurology, Rijnstate Hospital Arnhem, Arnhem, Netherlands4 aut |
| 700 | 1 | a Althaus, Katharinau Department of Neurology, Ulm University Hospital, Ulm, Germany4 aut |
| 700 | 1 | a Garambois, Katiau Stroke Unit, University Hospital of Grenoble, Grenoble, France4 aut |
| 700 | 1 | a Derex, Laurentu Department of Neurology, Hospices Civils de Lyon, Lyon, France4 aut |
| 700 | 1 | a Humbertjean, Lisau Stroke Unit, University Hospital of Nancy, Nancy, France4 aut |
| 700 | 1 | a Lebrato Hernandez, Luciau Department of Neurology, Virgen Del Rocio University Hospital, Seville, Spain4 aut |
| 700 | 1 | a Kellermair, Lukasu Department of Neurology, Johannes Kepler University Linz, Linz, Austria4 aut |
| 700 | 1 | a Morin Martin, Maru Department of Neurology, Hospital Complex of Toledo, Toledo, Spain4 aut |
| 700 | 1 | a Petruzzellis, Marcou Department of Neurology, AOU Consorziale Policlinico di Bari, Bari, Italy4 aut |
| 700 | 1 | a Cotelli, Mariau Department of Neurology, ASL Vallecamonica-Sebino, Breno, Italy4 aut |
| 700 | 1 | a Dubois, Marie-Cécileu Department of Anesthesia and Intensive Care, University Hospital of Poitiers, Poitiers, France4 aut |
| 700 | 1 | a Carvalho, Martau Department of Neurology, Centro Hospitalar Universitário de São João, Faculdade de Medicina, Universidade Do Porto, Porto, Portugal4 aut |
| 700 | 1 | a Wittstock, Matthiasu Department of Neurology, University Hospital Rostock, Rostock, Germany4 aut |
| 700 | 1 | a Miranda, Miguelu Department of Neurology, Hospital de Cascais Dr José de Almeida, Cascais, Portugal4 aut |
| 700 | 1 | a Skjelland, Monau Department of Neurology, Oslo University Hospital, Oslo, Norway4 aut |
| 700 | 1 | a Bandettini Di Poggio, Monicau Department of Neuroscience, Policlinic San Martino Hospital, Genoa, Italy4 aut |
| 700 | 1 | a Scholz, Moritz J.u Department of Neurology, Vivantes Auguste-Viktoria-Klinikum, Berlin, Germany4 aut |
| 700 | 1 | a Raposo, Nicolasu Department of Neurology, Toulouse University Hospital, Toulouse, France4 aut |
| 700 | 1 | a Kahnis, Robertu Department of Neurology, Toulouse University Hospital, Toulouse, France4 aut |
| 700 | 1 | a Kruyt, Nyikau Department of Neurology, Leiden University Medical Centre, Leiden, Netherlands4 aut |
| 700 | 1 | a Huet, Olivieru UFR de Bio-médecine, Hospital de la Cavale Blanche, CHRU de Brest, Brest, France4 aut |
| 700 | 1 | a Sharma, Pankaju Institute of Cardiovascular Research, Royal Holloway University of London, London, United Kingdom4 aut |
| 700 | 1 | a Candelaresi, Paolou Department of Neurology and Stroke, Cardarelli Hospital, Naples, Italy4 aut |
| 700 | 1 | a Reiner, Peggyu Department of Neurology, Lariboisière Hospital, Paris, France4 aut |
| 700 | 1 | a Vieira, Ricardou Department of Hematology, Universidade Federal Do Cariri, Juazeiro do Norte, Brazil4 aut |
| 700 | 1 | a Acampora, Robertou Department of Neurology, Ospedale Del Mare, Naples, Italy4 aut |
| 700 | 1 | a Kern, Rolfu Department of Neurology, Kempten Hospital, Kempten, Germany4 aut |
| 700 | 1 | a Leker, Ronenu Department of Neurology, Hadassah University Medical Center, Jerusalem, Israel4 aut |
| 700 | 1 | a Coutts, Shelaghu Department of Clinical Neurosciences, Radiology, and Community Health Sciences, Foothills Medical Centre, AL, Calgary, Canada4 aut |
| 700 | 1 | a Bal, Simerpreetu Department of Clinical Neurosciences, Radiology, and Community Health Sciences, Foothills Medical Centre, AL, Calgary, Canada4 aut |
| 700 | 1 | a Sharma, Shyam S.u Edinburgh Medical School, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Susen, Sophieu Department of Hematology and Transfusion, Lille University Hospital, Lille, France4 aut |
| 700 | 1 | a Cox, Thomasu Department of Neurology, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom4 aut |
| 700 | 1 | a Geeraerts, Thomasu Department of Anesthesiology and Critical Care, Toulouse University Hospital, Toulouse, France4 aut |
| 700 | 1 | a Gattringer, Thomasu Department of Neurology, Medical University of Graz, Graz, Austria4 aut |
| 700 | 1 | a Bartsch, Thorstenu Department of Neurology, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany4 aut |
| 700 | 1 | a Kleinig, Timothy J.u Department of Neurology, Royal Adelaide Hospital, Adelaide, Australia4 aut |
| 700 | 1 | a Dizonno, Vanessau Division of Neurology, University of British Columbia, Vancouver Stroke Program, BC, Vancouver, Canada4 aut |
| 700 | 1 | a Arslan, Yildizu Neurology Clinic, Medicana İzmir International Hospital, Izmir, Turkey4 aut |
| 710 | 2 | a Department of Neurology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlandsb Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte, University of Lisbon, Lisbon, Portugal4 org |
| 773 | 0 | t JAMA Neurologyd : American Medical Associationg 78:11, s. 1314-1323q 78:11<1314-1323x 2168-6149x 2168-6157 |
| 856 | 4 | u https://jamanetwork.com/journals/jamaneurology/articlepdf/2784622/jamaneurology_snchez_van_kammen_2021_oi_210063_1636576235.78072.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-191149 |
| 856 | 4 8 | u https://doi.org/10.1001/jamaneurol.2021.3619 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/310518 |
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