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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00007130naa a2200685 4500
001oai:DiVA.org:oru-81576
003SwePub
008200506s2020 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-815762 URI
024a https://doi.org/10.1136/openhrt-2018-0009472 DOI
040 a (SwePub)oru
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Kumsars, Indulisu Department of Cardiology, Latvia Center of Cardiology, Paul Stradins Clinical University Hospital, Riga, Latvia4 aut
2451 0a Randomised comparison of provisional side branch stenting versus a two-stent strategy for treatment of true coronary bifurcation lesions involving a large side branch :b the Nordic-Baltic Bifurcation Study IV
264 c 2020-01-19
264 1b BMJ Publishing Group Ltd,c 2020
338 a print2 rdacarrier
500 a Funding Agency:Cordis Corp
520 a Background: It is still uncertain whether coronary bifurcations with lesions involving a large side branch (SB) should be treated by stenting the main vessel and provisional stenting of the SB (simple) or by routine two-stent techniques (complex). We aimed to compare clinical outcome after treatment of lesions in large bifurcations by simple or complex stent implantation.Methods: The study was a randomised, superiority trial. Enrolment required a SB >= 2.75 mm, >= 50% diameter stenosis in both vessels, and allowed SB lesion length up to 15 mm. The primary endpoint was a composite of cardiac death, non-procedural myocardial infarction and target lesion revascularisation at 6 months. Two-year clinical follow-up was included in this primary reporting due to lower than expected event rates.Results: A total of 450 patients were assigned to simple stenting (n = 221) or complex stenting (n=229) in 14 Nordic and Baltic centres. Two-year follow-up was available in 218 (98.6%) and 228 (99.5%) patients, respectively. The primary endpoint of major adverse cardiac events (MACE) at 6 months was 5.5% vs 2.2% (risk differences 3.2%, 95% CI -0.2 to 6.8, p=0.07) and at 2 years 12.9% vs 8.4% (HR 0.63, 95% CI 0.35 to 1.13, p = 0.12) after simple versus complex treatment. In the subgroup treated by newer generation drug-eluting stents, MACE was 12.0% vs 5.6% (HR 0.45, 95% CI 0.17 to 1.17, p = 0.10) after simple versus complex treatment.Conclusion: In the treatment of bifurcation lesions involving a large SB with ostial stenosis, routine two-stent techniques did not improve outcome significantly compared with treatment by the simpler main vessel stenting technique after 2 years.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
700a Holm, Niels Ramsingu Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark4 aut
700a Niemelä, Mattiu Department of Cardiology, Oulu University Hospital, Oulu, Finland4 aut
700a Erglis, Andrejsu Research Institute of Cardiology and Regenerative Medicine, Latvia Centre of Cardiology, Riga, Latvia4 aut
700a Kervinen, Kariu Department of Cardiology, Oulu University Hospital, Oulu, Finland4 aut
700a Christiansen, Evald Hoju Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark4 aut
700a Maeng, Michaelu Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark4 aut
700a Dombrovskis, Andisu Department of Cardiology, Latvia Center of Cardiology, Paul Stradins Clinical University Hospital, Riga, Latvia4 aut
700a Abraitis, Vytautasu Department of Cardiology, Vilnius University Hospital, Vilnius, Lithuania4 aut
700a Kibarskis, Aleksandrasu Department of Cardiology, Vilnius University Hospital, Vilnius, Lithuania4 aut
700a Trovik, Thoru Department of Cardiology, University of North Norway, Tromsoe, Norway4 aut
700a Latkovskis, Gustavsu Research Institute of Cardiology and Regenerative Medicine, Latvia Centre of Cardiology, Riga, Latvia4 aut
700a Sondore, Daceu Department of Cardiology, Latvia Center of Cardiology, Paul Stradins Clinical University Hospital, Riga, Latvia4 aut
700a Narbute, Ingau Research Institute of Cardiology and Regenerative Medicine, Latvia Centre of Cardiology, Riga, Latvia4 aut
700a Terkelsen, Christian Juhlu Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark4 aut
700a Eskola, Markkuu Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, Finland4 aut
700a Romppanen, Hannuu Department of cardiology, Heart Center, Kuopio University Hospital, Kuopio, Finland4 aut
700a Laine, Mikau Department of Cardiology, Helsinki University Central Hospital, Helsinki, Finland4 aut
700a Jensen, Lisette Okkelsu Department of Cardiology, Odense University Hospital, Odense, Denmark4 aut
700a Pietila, Mikkou Department of Cardiology, Turku University Hospital, Turku, Finland4 aut
700a Gunnes, Palu Heart Center, Sørlandet Hospital, Arendal, Norway4 aut
700a Hebsgaard, Lasseu Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark4 aut
700a Fröbert, Ole,d 1964-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology4 aut0 (Swepub:oru)oft
700a Calais, Fredrik,d 1971-u Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Cardiology4 aut0 (Swepub:oru)fcs
700a Hartikainen, Juhau Department of cardiology, Heart Center, Kuopio University Hospital, Kuopio, Finland4 aut
700a Aarøe, Jensu Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark4 aut
700a Ravkilde, Janu Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark4 aut
700a Engstrøm, Thomasu Department of Cardiology, Rigshospitalet, Copenhagen, Denmark4 aut
700a Steigen, Terje K.u Department of Cardiology, University Hospital of North Norway, Tromsoe and Cardiovascular Diseases Research Group, UiT The Arctic University of Norway, Tromsø, Norway4 aut
700a Thuesen, Leifu Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark4 aut
700a Lassen, Jens F.u Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark4 aut
710a Department of Cardiology, Latvia Center of Cardiology, Paul Stradins Clinical University Hospital, Riga, Latviab Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark4 org
773t Open heartd : BMJ Publishing Group Ltdg 7:1q 7:1x 2053-3624
856u https://doi.org/10.1136/openhrt-2018-000947y Fulltext
856u https://openheart.bmj.com/content/openhrt/7/1/e000947.full.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-81576
8564 8u https://doi.org/10.1136/openhrt-2018-000947

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