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Sökning: WFRF:(De La Pena Moral Jesus M.) > Clinical Outcomes A...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005916naa a2200709 4500
001oai:DiVA.org:liu-189448
003SwePub
008221024s2022 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1894482 URI
0247 a https://doi.org/10.1097/SLA.00000000000045512 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Latenstein, Anouk E. J.u Univ Amsterdam, Netherlands4 aut
2451 0a Clinical Outcomes After Total Pancreatectomy A Prospective Multicenter Pan-European Snapshot Study
264 1b LIPPINCOTT WILLIAMS & WILKINS,c 2022
338 a print2 rdacarrier
520 a Objective: To assess outcomes among patients undergoing total pancreatectomy (TP) including predictors for complications and in-hospital mortality. Background: Current studies on TP mostly originate from high-volume centers and span long time periods and therefore may not reflect daily practice. Methods: This prospective pan-European snapshot study included patients who underwent elective (primary or completion) TP in 43 centers in 16 European countries (June 2018-June 2019). Subgroup analysis included cutoff values for annual volume of pancreatoduodenectomies (<60 vs >= 60). Predictors for major complications and in-hospital mortality were assessed in multivariable logistic regression. Results: In total, 277 patients underwent TP, mostly for malignant disease (73%). Major postoperative complications occurred in 70 patients (25%). Median hospital stay was 12 days (IQR 9-18) and 40 patients were readmitted (15%). In-hospital mortality was 5% and 90-day mortality 8%. In the subgroup analysis, in-hospital mortality was lower in patients operated in centers with >= 60 pancreatoduodenectomies compared <60 (4% vs 10%, P = 0.046). In multivariable analysis, annual volume <60 pancreatoduodenectomies (OR 3.78, 95% CI 1.18-12.16, P = 0.026), age (OR 1.07, 95% CI 1.01-1.14, P = 0.046), and estimated blood loss >= 2L (OR 11.89, 95% CI 2.64-53.61, P = 0.001) were associated with in-hospital mortality. ASA >= 3 (OR 2.87, 95% CI 1.56-5.26, P = 0.001) and estimated blood loss >= 2L (OR 3.52, 95% CI 1.25-9.90, P = 0.017) were associated with major complications. Conclusion: This pan-European prospective snapshot study found a 5% inhospital mortality after TP. The identified predictors for mortality, including low-volume centers, age, and increased blood loss, may be used to improve outcomes.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653 a clinical outcomes; in-hospital mortality; snapshot study; total pancreatectomy
7001 a Scholten, Lianneu Univ Amsterdam, Netherlands4 aut
7001 a Al-Saffar, Hasan Ahmadu Karolinska Univ Hosp, Sweden4 aut
7001 a Björnsson, Bergthoru Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US4 aut0 (Swepub:liu)berbj34
7001 a Butturini, Giovanniu Pederzoli Hosp, Italy4 aut
7001 a Capretti, Giovanniu Humanitas Clin & Res Ctr IRCCS, Italy; Humanitas Univ Dept Biomed Sci, Italy4 aut
7001 a Chatzizacharias, Nikolaos A.u Univ Hosp Birmingham NHS Trust, England4 aut
7001 a Dervenis, Chrisu Univ Cyprus, Cyprus4 aut
7001 a Frigerio, Isabellau Pederzoli Hosp, Italy4 aut
7001 a Gallagher, Tom K.u St Vincents Univ Hosp, Ireland4 aut
7001 a Gasteiger, Silviau Med Univ Innsbruck, Austria4 aut
7001 a Halimi, Asifu Karolinska Univ Hosp, Sweden4 aut
7001 a Labori, Knut J.u Oslo Univ Hosp, Norway4 aut
7001 a Montagnini, Gretau Univ & Hosp Trust Verona, Italy4 aut
7001 a Munoz-Bellvis, Luisu Univ Salamanca, Spain4 aut
7001 a Nappo, Gennarou Humanitas Clin & Res Ctr IRCCS, Italy; Humanitas Univ Dept Biomed Sci, Italy4 aut
7001 a Nikov, Andreju Cent Mil Hosp Prague, Czech Republic4 aut
7001 a Pando, Elizabethu Hosp Valle De Hebron, Spain4 aut
7001 a de Pastena, Matteou Univ & Hosp Trust Verona, Italy4 aut
7001 a De La Pena-Moral, Jesus M.u Hosp Clin Univ Virgen Arrixaca, Spain4 aut
7001 a Radenkovic, Dejanu Univ Belgrade, Serbia4 aut
7001 a Roberts, Keith J.u Univ Hosp Birmingham NHS Trust, England4 aut
7001 a Salvia, Robertou Univ & Hosp Trust Verona, Italy4 aut
7001 a Sanchez-Bueno, Franciscou Hosp Clin Univ Virgen Arrixaca, Spain4 aut
7001 a Scandavini, Chiarau Karolinska Univ Hosp, Sweden4 aut
7001 a Serradilla-Martin, Mariou Miguel Servet Univ Hosp, Spain4 aut
7001 a Stattner, Stefanu Med Univ Innsbruck, Austria; Salzkammergut Klinikum, Austria4 aut
7001 a Tomazic, Alesu Univ Med Ctr Ljubljana, Slovenia4 aut
7001 a Varga, Martinu Paracelsus Med Univ, Austria4 aut
7001 a Zavrtanik, Hanau Univ Med Ctr Ljubljana, Slovenia4 aut
7001 a Zerbi, Alessandrou Humanitas Clin & Res Ctr IRCCS, Italy; Humanitas Univ Dept Biomed Sci, Italy4 aut
7001 a Erkan, Mertu Koc Univ, Turkey4 aut
7001 a Kleeff, Jorgu Martin Luther Univ Halle Wittenberg, Germany4 aut
7001 a Lesurtel, Mickaelu Univ Lyon 1, France4 aut
7001 a Besselink, Marc G.u Univ Amsterdam, Netherlands4 aut
7001 a Ramia-Angel, Jose M.u Univ Hosp Guadalajara, Spain4 aut
7102 a Univ Amsterdam, Netherlandsb Karolinska Univ Hosp, Sweden4 org
7730 t Annals of Surgeryd : LIPPINCOTT WILLIAMS & WILKINSg 276:5, s. E536-E543q 276:5<E536-E543x 0003-4932x 1528-1140
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-189448
8564 8u https://doi.org/10.1097/SLA.0000000000004551

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