Sökning: WFRF:(Delesque Touchard Nathalie) > Gas6 promotes infla...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03237naa a2200553 4500 | |
001 | oai:lup.lub.lu.se:4492e023-ecd3-46da-9298-060ce0907772 | |
003 | SwePub | |
008 | 160401s2008 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/12055802 URI |
024 | 7 | a https://doi.org/10.1182/blood-2007-05-0895652 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Tjwa, Marc4 aut |
245 | 1 0 | a Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes |
264 | 1 | b American Society of Hematology,c 2008 |
520 | a The role of Gas6 in enclothelial cell (EC) function remains incompletely characterized. Here we report that Gas6 amplifies EC activation in response to inflammatory stimuli in vitro. In vivo, Gas6 promotes and accelerates the sequestration of circulating platelets and leukocytes on activated endothelium as well as the formation and enclothelial sequestration of circulating platelet-leukocyte conjugates. In addition, Gas6 promotes leukocyte extravasation, inflammation, and thrombosis in mouse models of inflammation (endotoxinemia, vasculitis, heart transplantation). Thus, Gas6 amplifies EC activation, thereby playing a key role in enhancing the interactions between ECs, platelets, and leukocytes during inflammation. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng |
700 | 1 | a Ido-Martin, Lola Bell4 aut |
700 | 1 | a Lin, Yuan4 aut |
700 | 1 | a Lutgens, Esther4 aut |
700 | 1 | a Plaisance, Stephane4 aut |
700 | 1 | a Bono, Francoise4 aut |
700 | 1 | a Delesque-Touchard, Nathalie4 aut |
700 | 1 | a Herve, Caroline4 aut |
700 | 1 | a Moura, Rute4 aut |
700 | 1 | a Billiau, An D4 aut |
700 | 1 | a Aparicio, Cristina4 aut |
700 | 1 | a Levi, Marcel4 aut |
700 | 1 | a Daemen, Mat4 aut |
700 | 1 | a Dewerchin, Mieke4 aut |
700 | 1 | a Lupu, Florea4 aut |
700 | 1 | a Arnout, Jef4 aut |
700 | 1 | a Herbert, Jean-Marc4 aut |
700 | 1 | a Waer, Mark4 aut |
700 | 1 | a Garcia de Frutos, Pablou Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)klke-pga |
700 | 1 | a Dahlbäck, Björnu Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)klke-bda |
700 | 1 | a Carmeliet, Peter4 aut |
700 | 1 | a Hoylaerts, Marc F4 aut |
700 | 1 | a Moons, Lieve4 aut |
710 | 2 | a Klinisk kemi, Malmöb Forskargrupper vid Lunds universitet4 org |
773 | 0 | t Bloodd : American Society of Hematologyg 111:8, s. 4096-4105q 111:8<4096-4105x 1528-0020x 0006-4971 |
856 | 4 | u http://dx.doi.org/10.1182/blood-2007-05-089565x freey FULLTEXT |
856 | 4 | u https://digital.csic.es/bitstream/10261/37139/1/Gas6%20promotes.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/1205580 |
856 | 4 8 | u https://doi.org/10.1182/blood-2007-05-089565 |
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