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  • Raj, Satish RUniversity of Calgary (author)

Postural orthostatic tachycardia syndrome (POTS) : Priorities for POTS care and research from a 2019 National Institutes of Health Expert Consensus Meeting - Part 2

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • Elsevier BV,2021

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:72d87dd1-a0eb-449d-b928-12e50d8bd920
  • https://lup.lub.lu.se/record/72d87dd1-a0eb-449d-b928-12e50d8bd920URI
  • https://doi.org/10.1016/j.autneu.2021.102836DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • The National Institutes of Health hosted a workshop in 2019 to build consensus around the current state of understanding of the pathophysiology of postural orthostatic tachycardia syndrome (POTS) and to identify knowledge gaps that must be addressed to enhance clinical care of POTS patients through research. This second (of two) articles summarizes current knowledge gaps, and outlines the clinical and research priorities for POTS. POTS is a complex, multi-system, chronic disorder of the autonomic nervous system characterized by orthostatic intolerance and orthostatic tachycardia without hypotension. Patients often experience a host of other related disabling symptoms. The functional and economic impacts of this disorder are significant. The pathophysiology remains incompletely understood. Beyond the significant gaps in understanding the disorder itself, there is a paucity of evidence to guide treatment which can contribute to suboptimal care for this patient population. The vast majority of physicians have minimal to no familiarity or training in the assessment and management of POTS. Funding for POTS research remains very low relative to the size of the patient population and impact of the syndrome. In addition to efforts to improve awareness and physician education, an investment in research infrastructure including the development of standardized disease-specific evaluation tools and outcome measures is needed to facilitate effective collaborative research. A national POTS research consortium could facilitate well-controlled multidisciplinary clinical research studies and therapeutic trials. These priorities will require a substantial increase in the number of research investigators and the amount of research funding in this area.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Bourne, Kate MUniversity of Calgary (author)
  • Stiles, Lauren EStony Brook University (author)
  • Miglis, Mitchell GStanford University (author)
  • Cortez, Melissa MUtah State University (author)
  • Miller, Amanda JPennsylvania State University College of Medicine (author)
  • Freeman, RoyHarvard Medical School (author)
  • Biaggioni, ItaloVanderbilt University (author)
  • Rowe, Peter CJohns Hopkins University (author)
  • Sheldon, Robert SUniversity of Calgary (author)
  • Shibao, Cyndya AVanderbilt University (author)
  • Diedrich, AndreVanderbilt University (author)
  • Systrom, David MHarvard Medical School (author)
  • Cook, Glen AUniformed Services University of the Health Sciences (author)
  • Doherty, Taylor AUniversity of California, San Diego (author)
  • Abdallah, Hasan IChildren's Heart Institute (author)
  • Grubb, Blair PThe University of Toledo Medical Center (author)
  • Fedorowski, ArturLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Department of Clinical Sciences, Malmö,Faculty of Medicine,Cardiovascular Research - Hypertension,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-afr (author)
  • Stewart, Julian MNew York Medical College (author)
  • Arnold, Amy CVanderbilt University (author)
  • Pace, Laura AUtah State University (author)
  • Axelsson, JonasKarolinska University Hospital(Swepub:lu)jo0150ax (author)
  • Boris, Jeffrey RJeffrey R Boris MD LLC (author)
  • Moak, Jeffrey PGeorge Washington University (author)
  • Goodman, Brent PMayo Clinic Scottsdale-Phoenix, Arizona (author)
  • Chémali, Kamal REastern Virginia Medical School (author)
  • Chung, Tae HJohns Hopkins University (author)
  • Goldstein, David SNational Health Research Institutes Taiwan (NHRI) (author)
  • Darbari, AnilGeorge Washington University (author)
  • Vernino, StevenUniversity of Texas Southwestern Medical Center (author)
  • University of CalgaryStony Brook University (creator_code:org_t)

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