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FältnamnIndikatorerMetadata
00009286naa a2200877 4500
001oai:DiVA.org:uu-376811
003SwePub
008190222s2019 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-155668
009oai:gup.ub.gu.se/274368
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3768112 URI
0247 a https://doi.org/10.1016/j.maturitas.2018.11.0072 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1556682 URI
0247 a https://gup.ub.gu.se/publication/2743682 URI
040 a (SwePub)uud (SwePub)umud (SwePub)gu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Triebner, Kaiu Univ Bergen, Dept Clin Sci, Jonas Lies Veg 87, N-5021 Bergen, Norway;Univ Bergen, Core Facil Metabol, Jonas Lies Veg 87, N-5021 Bergen, Norway4 aut
2451 0a Exogenous female sex steroids may reduce lung ageing after menopause :b A 20-year follow-up study of a general population sample (ECRHS)
264 1b ELSEVIER IRELAND LTD,c 2019
338 a electronic2 rdacarrier
520 a Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The effects of HRT on lung function decline, hence lung ageing, have not yet been investigated despite the recognized effects of HRT on other health outcomes. Study design: The population-based multi-centre European Community Respiratory Health Survey provided complete data for 275 oral HRT users at two time points, who were matched with 383 nonusers and analysed with a two-level linear mixed effects regression model. Main outcome measures: We studied whether HRT use was associated with the annual decline in forced vital capacity (FVC) and forced expiratory volume in one second (FEV1). Results: Lung function of women using oral HRT for more than five years declined less rapidly than that of nonusers. The adjusted difference in FVC decline was 5.6 mL/y (95%CI: 1.8 to 9.3, p = 0.01) for women who had taken HRT for six to ten years and 8.9 mL/y (3.5 to 14.2, p = 0.003) for those who had taken it for more than ten years. The adjusted difference in FEV1 decline was 4.4 mL/y (0.9 to 8.0, p = 0.02) with treatment from six to ten years and 5.3 mL/y (0.4 to 10.2, p = 0.048) with treatment for over ten years. Conclusions: In this longitudinal population-based study, the decline in lung function was less rapid in women who used HRT, following a dose-response pattern, and consistent when adjusting for potential confounding factors. This may signify that female sex hormones are of importance for lung ageing.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653 a Hormone replacement therapy (HRT)
653 a Lung function
653 a Menopause
653 a Reproductive aging
653 a Sex hormones
653 a Hormone replacement therapy (HRT)
653 a Lung function
653 a Menopause
653 a Reproductive aging
653 a Sex hormones
7001 a Accordini, Simoneu Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Inst Biol 2, Str Le Grazie 8, I-37134 Verona, Italy4 aut
7001 a Calciano, Luciau Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Inst Biol 2, Str Le Grazie 8, I-37134 Verona, Italy4 aut
7001 a Johannessen, Aneu Haukeland Hosp, Dept Occupat Med, Jonas Lies Vei 65, N-5021 Bergen, Norway;Univ Bergen, Ctr Int Hlth, Jekteviksbakken 31, N-5009 Bergen, Norway4 aut
7001 a Benediktsdottir, Bryndisu Univ Iceland, Fac Med, Reykjavik, Iceland4 aut
7001 a Bifulco, Ersiliau Univ Bergen, Dept Clin Sci, Jonas Lies Veg 87, N-5021 Bergen, Norway;Univ Bergen, Core Facil Metabol, Jonas Lies Veg 87, N-5021 Bergen, Norway4 aut
7001 a Demoly, Pascalu Univ Montpellier, Univ Hosp Montpellier, Dept Pulmonol, Div Allergy, 371 Ave Doyen Gaston Giraud, F-34295 Montpellier, France;Sorbonne Univ, French Natl Inst Hlth & Med Res, Pierre Louis Inst Epidemiol & Publ Hlth, 56 Blvd Vincent Auriol, F-75646 Paris, France4 aut
7001 a Dharmage, Shyamali C.u Univ Melbourne, Melbourne Sch Populat & Global Hlth, Allergy & Lung Hlth Unit, 207 Bouverie St, Carlton, Vic 3052, Australia4 aut
7001 a Franklin, Karl A.u Umeå universitet,Kirurgi,Umea Univ, Dept Surg & Perioperat Sci, Koksvagen 11, S-90185 Umea, Sweden4 aut0 (Swepub:umu)kafr0021
7001 a Garcia-Aymerich, Judithu ISGlobal, Doctor Aiguader 88, Barcelona 08003, Spain;Univ Pompeu Fabra, Doctor Aiguader 88, Barcelona 08003, Spain;CIBER Epidemiol & Publ Hlth, Doctor Aiguader 88, Barcelona 08003, Spain4 aut
7001 a Gullon Blanco, Jose Antoniou Univ Hosp San Agustin, Dept Pneumol, Camino Heros 4, Aviles 33410, Spain4 aut
7001 a Heinrich, Joachimu Ludwig Maximilian Univ Munich, Inst & Outpatient Clin Occupat Social & Environm, Ziemssenstr 1, D-80336 Munich, Germany4 aut
7001 a Holm, Mathias,d 1969u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för arbets-och miljömedicin,Institute of Medicine, Department of Public Health and Community Medicine, Section of Occupational and environmental medicine4 aut0 (Swepub:gu)xhomat
7001 a Jarvis, Debbieu Imperial Coll, Natl Heart & Lung Inst, 1b Manresa Rd, London SW3 6LR, England4 aut
7001 a Jogi, Rainu Uppsala universitet,Lung- allergi- och sömnforskning,Tartu Univ Hosp, Lung Clin, Dept Lung Med, Riia 167, EE-51014 Tartu, Estonia4 aut0 (Swepub:uu)raijo735
7001 a Lindberg, Evau Uppsala universitet,Lung- allergi- och sömnforskning4 aut0 (Swepub:uu)evalb
7001 a Martinez-Moratalla, Jesusu Hlth Serv Castilla La Mancha, Pulmonol Serv, Albacete Univ Hosp Complex, Albacete, Spain;Castilla La Mancha Univ, Fac Med Albacete, Albacete, Spain4 aut
7001 a Muniozguren Agirre, Nereau Basque Govt, Dept Hlth, Unit Epidemiol & Publ Hlth, Alameda Rekalde 39A, Bilbao 48008, Spain4 aut
7001 a Pin, Isabelleu Univ Grenoble Alpes, Univ Hosp Grenoble Alpes, French Natl Inst Hlth & Med Res, Inst Adv Biosci,Dept Pediat, CS 10217, F-38043 Grenoble 9, France4 aut
7001 a Probst-Hensch, Nicoleu Swiss Trop & Publ Hlth Inst, Socinstr 58, CH-4002 Basel, Switzerland;Univ Basel, Dept Publ Hlth, Peterspl 1, CH-4001 Basel, Switzerland4 aut
7001 a Raherison, Chantalu Bordeaux Univ, Bordeaux Populat Hlth Res, U1219, 146 Rue Leo Saignat, F-33076 Bordeaux, France4 aut
7001 a Luis Sanchez-Ramos, Joseu Univ Huelva, Dept Nursing, Ave Tres Marzo S-N, Huelva 21071, Spain4 aut
7001 a Schlunssen, Viviu Aarhus Univ, Dept Publ Hlth, Bartholins Alle 2, DK-8000 Aarhus, Denmark;Natl Res Ctr Working Environm, Lerso Pk Alle 105, DK-2100 Copenhagen, Denmark4 aut
7001 a Svanes, Cecilieu Haukeland Hosp, Dept Occupat Med, Jonas Lies Vei 65, N-5021 Bergen, Norway;Univ Bergen, Ctr Int Hlth, Jekteviksbakken 31, N-5009 Bergen, Norway4 aut
7001 a Hustad, Steinaru Univ Bergen, Dept Clin Sci, Jonas Lies Veg 87, N-5021 Bergen, Norway;Univ Bergen, Core Facil Metabol, Jonas Lies Veg 87, N-5021 Bergen, Norway4 aut
7001 a Leynaert, Benedicteu French Natl Inst Hlth & Med Res, UMR1152, Team Epidemiol, Paris, France4 aut
7001 a Real, Francisco Gomezu Univ Bergen, Dept Clin Sci, Jonas Lies Veg 87, N-5021 Bergen, Norway;Haukeland Hosp, Dept Gynecol & Obstet, Jonas Lies Veg 65, N-5021 Bergen, Norway4 aut
7102 a Univ Bergen, Dept Clin Sci, Jonas Lies Veg 87, N-5021 Bergen, Norway;Univ Bergen, Core Facil Metabol, Jonas Lies Veg 87, N-5021 Bergen, Norwayb Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Inst Biol 2, Str Le Grazie 8, I-37134 Verona, Italy4 org
7730 t Maturitasd : ELSEVIER IRELAND LTDg 120, s. 29-34q 120<29-34x 0378-5122x 1873-4111
8564 u https://uu.diva-portal.org/smash/get/diva2:1291065/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://www.maturitas.org/article/S0378-5122(18)30602-9/pdf
8564 u https://doi.org/10.1016/j.maturitas.2018.11.007y Fulltext
8564 u https://umu.diva-portal.org/smash/get/diva2:1282556/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-376811
8564 8u https://doi.org/10.1016/j.maturitas.2018.11.007
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-155668
8564 8u https://gup.ub.gu.se/publication/274368

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