Health-related quality of life in patients with lower limb amputation - an assessment of the measurement properties of EQ-5D-3L and EQ-5D-5L using data from the Swedish Amputation and Prosthetics Registry

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Fältnamn	Indikatorer	Metadata
000		03965naa a2200553 4500
001		oai:gup.ub.gu.se/312770
003		SwePub
008		240910s2022 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:148377920
024	7	a https://gup.ub.gu.se/publication/3127702 URI
024	7	a https://doi.org/10.1080/09638288.2021.20156282 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1483779202 URI
040		a (SwePub)gud (SwePub)ki
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Ernstsson, O.u Karolinska Institutet4 aut
245	1 0	a Health-related quality of life in patients with lower limb amputation - an assessment of the measurement properties of EQ-5D-3L and EQ-5D-5L using data from the Swedish Amputation and Prosthetics Registry
264		c 2021-12-21
264	1	b Informa UK Limited,c 2022
520		a Purpose To assess the measurement properties of EQ-5D-3L and EQ-5D-5L in patients with a major lower limb amputation (LLA). Methods This was a retrospective register-based study using data from the Swedish Amputation and Prosthetics Registry (SwedeAmp). Patients with a six-months follow-up (including either EQ-5D-3L or EQ-5D-5L) after a major unilateral LLA were included. The measurement properties of EQ-5D-3L and EQ-5D-5L were compared in terms of feasibility, response patterns, informativity, and convergent and known-group validity. Results The sample included 700 patients with below-knee amputation (76%), above-knee amputation (18%), or knee disarticulation (7%). Responses to EQ-5D-3L and -5L were similar regarding feasibility (98% completion rate) and the proportion reporting no problems (7% and 6%). Compared to EQ-5D-3L, EQ-5D-5L showed higher absolute and relative informativity in all dimensions, with the largest improvement in the mobility dimension. In the analyses of convergent validity, the EQ-5D-5L generally showed stronger correlations with disease-specific measures. Only EQ-5D-5L was able to discriminate between subgroups with different amputation levels. Conclusion The findings support the use of EQ-5D-5L over EQ-5D-3L in patients with an LLA, mainly due to improved informativity and improved convergent and known-group validity.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Annan hälsovetenskap0 (SwePub)303992 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Other Health Sciences0 (SwePub)303992 hsv//eng
653		a EQ-5D
653		a quality of life
653		a validity
653		a feasibility
653		a amputation
653		a registries
653		a validity
653		a reliability
653		a complications
653		a population
653		a Rehabilitation
700	1	a Hagberg, Kerstin,d 1957u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för ortopedi,Institute of Clinical Sciences, Department of Orthopaedics4 aut0 (Swepub:gu)xhagbk
700	1	a Janssen, M. F.4 aut
700	1	a Bonsel, G. J.4 aut
700	1	a Korkmaz, S.4 aut
700	1	a Zethraeus, N.u Karolinska Institutet4 aut
700	1	a Heintz, E.u Karolinska Institutet4 aut
710	2	a Karolinska Institutetb Institutionen för kliniska vetenskaper, Avdelningen för ortopedi4 org
773	0	t Disability and Rehabilitationd : Informa UK Limitedg 44:26, s. 8471-8479q 44:26<8471-8479x 0963-8288x 1464-5165
856	4	u https://doi.org/10.1080/09638288.2021.2015628
856	4 8	u https://gup.ub.gu.se/publication/312770
856	4 8	u https://doi.org/10.1080/09638288.2021.2015628
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:148377920

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Orthopaedics

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Other Health Sci ...

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